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Ebola Outbreak 2014 2015 by Dr. Fauci

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microbe subway map

Explore an awesome map of microbes on the NY subways for yourself! Read More

Microbes scared to death by virus presence

A recent study published in mBio suggests that certain archaea go dormant in the presence of bacteriophage viruses, ceasing to reproduce or carry on cellular processes essential to their survival. The study, which was conducted at the University of Illinois, sheds light on the co-evolution of a... Read More

TWiM 101 Letters

Eric writes:


Dear TWIMers,


I am a retired computer programmer and also a free market libertarian. I listened to a recent podcast where the subject of mandatory hand washing by food workers was tossed around. I would like to present a few more of the free marke... Read More

TWiV 330: A swinging gate

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

New mechanisms of 'social networking' in bacteria

AMHERST, Mass. - Bacteria have traditionally been viewed as solitary organisms that "hang out on their own," says molecular biologist Kevin Griffith of the University of Massachusetts Amherst. However, scientists now realize that in fact, bacteria exhibit social behavior within groups. Read More

CRISPR-Cas editing of C. albicans holds promise for overcoming deadly fungal infections

CAMBRIDGE, Mass. (April 3, 2015) - By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there... Read More

Unearthing new antivirals

SAN DIEGO (April 14, 2015) -- A team of biologists from San Diego State University has developed a platform for identifying drugs that could prove to be effective against a variety of viral diseases. In a pair of recent articles in the Journal of Biomolecular Screening and the Journal of Visuali... Read More

Sierra Leone: Ebola Trial Begins

An Ebola vaccine candidate that has been successful in non-human primates is being tested on volunteers in Sierra Leone this month, where two new cases were reported as of Monday. Read More

BacterioFiles 210 - Archaea Acquired Alternative Abilities

This episode: Genes taken from bacteria may have been important for the evolution of distinct groups of archaea!


(7.4 MB, 8 minutes)


Show notes: 
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How a deadly fungus evades the immune system

The fungus Candida albicans, which can be fatal in up to 40% of patients with a systemic infection, is being reconsidered by a team of researchers from the University of Toronto. They investigated alternative explanations to the previously accepted thought that the fungus undergoes a change in ... Read More

Cold Spring Harbor Lab, Seeking Human Subjects, Teams Up With Hospital System

Some of the world’s finest scientists live in a former whaling village on the North Shore of Long Island, in a compound reminiscent of an army post.

In this pastoral setting, they have very self-consciously taken themselves out of the real world into a cerebral one, where they are searching f... Read More

Six questions about HIV/AIDS that deserve more attention

As HIV investigators work to control and eradicate the virus worldwide, certain myths or misconceptions about the disease have been embraced, whereas other concepts with merit have been left relatively unexplored, argues American HIV/AIDS researcher Jay Levy, MD, in a commentary publishing April... Read More

Purging a virus from organ transplants

Human cytomegalovirus (HCMV) is an extremely common virus, which as other members of the herpes virus family causes life-long infections in humans. Most individuals are exposed to HCMV during childhood, yet symptoms can be easily fought off by a healthy immune system. However, infections can be ... Read More

CRISPR-Cas genome editing of Candida albicans holds promise for overcoming deadly fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans’ genome systematically—an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal... Read More

Scientists reveal unique mechanism of natural product with powerful antimicrobial action

A research team at the Scripps Research Institute in Florida has published a study which details the wide-range of function of the natural product borrelidin. Borrelidin is a powerful tRNA-synthetase inhibitor which has been shown to exhibit antimicrobial characteristics, including anti-bacteri... Read More

Shape-shifting molecule tricks viruses into mutating themselves to death

A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus's genetic material. The findings from the University of Chicago and the Massachusetts Institute of Technology could bolster efforts ... Read More

Three Roads to Cellular Compartments

In a recent post to ASM's blog Small Things Considered, Merry Youle writes a wonderful, sometimes thrilling description of the different forms of cellular compartments that have evolved over the last 4 billion years or so. From compartmentalized, lipid-bound membranes in eukaryotes to microcomp... Read More

The 'intraterrestrials': New viruses discovered in ocean depths

Deep sea microbiology is a rapidly-growing field that we know (not surprisingly) very little about. New research investigates the ecology of methane seep ecosystems and the interaction between archaea and viruses beneath the ocean floor. A newly-discovered virus seems to self-select for mutati... Read More

Yes, We Were Warned About Ebola

"The conventional wisdom among public health authorities is that the Ebola virus, which killed at least 10,000 people in Liberia, Sierra Leone and Guinea, was a new phenomenon, not seen in West Africa before 2013. (The one exception was an anomalous case in Ivory Coast in 1994, when a Swiss prim... Read More

These 6 Symptoms predict Ebola risk

When deciding whether a sick patient belongs in an Ebola treatment unit (ETU), doctors want to be right because any misdiagnosis is terribly dangerous.

Returning an Ebola case to the community leaves a patient untreated and prolongs the epidemic, but admitting someone with a different illness... Read More
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