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The typhoid fever pathogen uses a cloaking mechanism to evade neutrophil neutralization

Typhoid fever is caused by systemic infection with Salmonella enterica Typhi. In contrast, infection with the closely related bacterium Salmonella enterica Thyphimurium is usually limited to the gut and causes less serious diarrheal disease. Research comparing the two pathogens reveals how S. Ty... Read More

TWiV 299: Rocky Mountain virology

Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases.


Host: Vincent ... Read More

From bite site to brain: How rabies virus hijacks and speeds up transport in nerve cells

Rabies is usually transmitted through the bite of an infected animal into muscle tissue of the new host. From there, the virus travels all the way to the brain where it multiplies and causes the usually fatal disease. A new article sheds light on how the virus hijacks the transport system in ner... Read More

BacterioFiles 181 - Spore-formers Smash Salmonella's Solanum Strongholds

This episode: Soil bacteria could help prevent food poisoning from bacteria in raw tomatoes!


(9.6 MB, 10.5 minutes)


Show notes: 
News item<... Read More

Self-Assembly For Me

I have the grating feeling that the subject of self-assembly of complex biological structures may not always amass the level of respect it deserves. I reckon that its importance is generally appreciated but, as topics go, it tends at times to be set aside. Yet, this is one of the most magnificen... Read More

Zaire ebolavirus in West Africa

Dr. Tom Solomon is Director of the Institute for Infection and Global Health at the University of Liverpool. In this video he speaks with Vincent Racaniello about the 2014 outbreak of Zaire ebolavirus in West Africa. Dr. Solomon discusses why the epidemic has spread, how it might be curtailed, t... Read More

Zombie bacteria are nothing to be afraid of

Recently identified cell-cycle controls are targets for new drugs that fight infections by shutting down division.

A cell is not a soap bubble that can simply pinch in two to reproduce. The ability to faithfully copy genetic material and distribute it equally to daughter cells is fundamental ... Read More

‘Wormy’ Pills Might Fend Off Autoimmune Diseases

Scientists have identified peptides from parasitic hookworms that can calm the body’s immune response and perhaps pave the way to treat autoimmune diseases.

Experts believe the peptide molecules could help explain why worm infections can effectively treat diseases such as multiple sclerosis, ... Read More

Progress in the fight against harmful fungi

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. Molecular analysis of the Candida glabrata fungus mutations led to the discovery of 28 new genes that are partly respon... Read More

TWiV 300: So happy together

Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent  speaks with Dickson, Alan, Rich, and Kathy about their careers in science.


Hosts:  Read More

Ebola genomes sequenced

Speedy analysis reveals mutations, insights into outbreak, along with clues to origin, spread.

Responding rapidly to the deadly outbreak of Ebola virus disease (EVD) in West Africa, a team of researchers from the Broad Institute and Harvard University, working with the Sierra Leone Ministry o... Read More

Should experimental drugs be used in the Ebola outbreak?

Risks and benefits of unproven treatments, as World Health Organization approves use in crisis.

Two Liberian doctors are set to become the first Africans to receive an experimental drug against the Ebola virus. The news comes as the World Health Organization concludes that it is ethical to us... Read More

Catching Up, Part I: Meeting with Former Research Students at ASM in Boston in May.

In this post, I meet up with six of my former undergraduate students at the General Meeting of the American Society of Microbiology in Boston last May. We had a great dinner where we could catch up on challenges and cheer each other on. I am very proud of the great students in this post, who a... Read More

Scientists develop ‘electronic nose’ for rapid detection of C-diff infection

A fast-sensitive “electronic-nose” for sniffing the highly infectious bacteria C-diff, that causes diarrhoea, temperature and stomach cramps, has been developed by a team at the University of Leicester.

Using a mass spectrometer, the research team has demonstrated that it is possible to ident... Read More
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