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Single-dose, needle-free Ebola vaccine provides long-term protection in macaques

Scientists have demonstrated for the first time that a single-dose, needleless Ebola vaccine given to primates through their noses and lungs protected them against infection for at least 21 weeks. A vaccine that doesn’t require an injection could help prevent passing along infections through uni... Read More

New drug could make vaccines more effective in the elderly

Oxford University scientists have developed a new method of boosting the ageing immune system using a naturally occurring chemical compound.

Early tests in mice carried out by the research team have shown that the compound restores the immune system's inbuilt 'memory', enabling the body to mo... Read More

U.S. Ebola researchers plead for access to virus samples

Scientists across the United States say they cannot obtain samples of Ebola, complicating efforts to understand how the virus is mutating and develop new drugs, vaccines and diagnostics.

The problems reflect growing caution by regulators and transport companies about handling Ebola as well as... Read More

GW Researcher Adapting Breakthrough Technologies to Combat Parasitic Worm Infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approx... Read More

Using microscopic bugs to save the bees

For decades, honeybees have been battling a deadly disease that kills off their babies (larvae) and leads to hive collapse. It’s called American Foulbrood and its effects are so devastating and infectious, it often requires infected hives to be burned to the ground.

Treating Foulbrood is comp... Read More

Line dancing bacteria on a chip (w/ Video)

By changing the direction of a magnetic field, so-called magneto-tactic bacteria are able to make a full U-turn. They can be taught line dancing in this way, inside the tiny micro channels of a lab on a chip. Magnetically steered objects will be capable of delivering medication, for example. Sci... Read More

Genetic tweak gave yellow fever mosquitoes a nose for human odor

One of the world’s deadliest mosquitoes sustains its taste for human blood thanks in part to a genetic tweak that makes it more sensitive to human odor, according to new research.

Researchers report in the journal Nature that the yellow fever mosquito contains a version of an odor-detecting g... Read More

Pre-symptomatic markers for hemorrhagic viruses like Ebola identified

It is possible to distinguish between different hemorrhagic fevers, including Marburg (Ebola cousin) and Lassa before the person becomes symptomatic, new research has found. This study will allow for the development of better diagnostics, especially during the early stages of disease, when treat... Read More

Targeting key cells for a dengue virus infection model

Dengue virus infects hundreds of millions of people living in tropical countries every year. Transmitted via mosquito bites, the virus typically causes fever, but may also lead to potentially fatal organ failure. The development of mouse models of dengue virus infection could hasten an effective... Read More

Ebola and the Vast Viral Universe

Behind the hellish Ebola epidemic ravaging West Africa lies an agent that fittingly embodies the mad contradictions of a nightmare. It is alive yet dead, simple yet complex, mindless yet prophetic, seemingly able to anticipate our every move.

For scientists who study the evolution and behavio... Read More

Microbiome Studies Contaminated By Sequencing Supplies

Non-sterile lab reagents and DNA extraction kits add their own assortment of DNA to microbiome samples.

In this age of cheap DNA technology, scientists are sequencing every sample they can get their hands on. They've ID'd the microbes in mosquito guts, coral mucus and frog skin; in polar ice;... Read More

BacterioFiles 190 - Bacteriophages Bust Biofilm Beacons

This episode: Engineered phages can both kill bacteria and disrupt their communications!


(14.8 MB, 16.2 minutes)


Show notes: 
Journal Paper


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Crowdsourcing To Solve Microbe Mysteries

Scientists hope to unlock the secrets of millions of marine microbes from waters as far apart as Sydney’s Botany Bay and the Amazon River in Brazil, with the help of an international team of volunteers sharing their spare computer capacity to create a research “supercomputer”.

The project, co... Read More

Virus Sleuths Chip Away At Ebola Mysteries

Vincent Racaniello, who studies viruses at Columbia University, says Ebola has recently become his obsession.

"I find myself reading incessantly about Ebola when I should be doing other things," says Racaniello, host of the online show This Week in Virology, which has devoted several recent p... Read More

Virus devastating sea stars on Pacific Coast identified

Scientists have now explained the mysteriously sudden appearance of a disease that has decimated sea stars on the North American Pacific Coast.

In a paper published Monday, November 17, 2014 in the journal Proceedings of the National Academy of Sciences, Cornell University microbiologist Ian ... Read More

How Bacteria In The Gut Help Fight Off Viruses

If it was a snake, it would have bitten us.

The secret to stopping a deadly stomach virus may be sitting right there in our guts, scientists reported Thursday in the journal Science. Or more specifically, the treatment is in our microbiome — the trillions of bacteria that inconspicuously hang... Read More

Ebola Exacerbates West Africa’s Poverty Crisis

The virus spreading in Guinea, Liberia and Sierra Leone has led to food shortages and neglect of other devastating tropical illnesses.

When Ebola came to Dorcas's home on the outskirts of Freetown in Sierra Leone, the virus spared no one. Her mother brought it home from the clinic where she w... Read More

This Device Diagnoses Hundreds of Diseases Using a Single Drop of Blood

The digital health revolution is still stuck.

Tech giants are jumping into the fray with fitness offerings like Apple Health and Google Fit, but there’s still not much in the way of, well, actual medicine. The Fitbits and Jawbones of the world measure users’ steps and heart rate, but they don... Read More

Koala chlamydia vaccine trial raises hope

Australian scientists say they have successfully tested a vaccine aimed at protecting wild koalas from chlamydia.

The disease has ravaged the native marsupial, which is under increasing threat.

Microbiologists in Queensland now hope to protect some of the remaining population after success... Read More

More attention to measles, vaccine experts urge

Doctors and public health authorities need to renew their attention to measles, researchers from Emory Vaccine Center urge in an editorial in the New England Journal of Medicine.

"Because of its high level of contagiousness, measles is the indicator disease for weaknesses of an immunization p... Read More
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