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Lingering lymphocytes lash out against Leishmania

Immune cells that hang around after parasitic skin infection help ward off secondary attack, according to a study in The Journal of Experimental Medicine. These skin squatters may prove to be the key to successful anti-parasite vaccines. Read More

Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease. Read More

BacterioFiles 222 - Cells Store Solar Sparks

This episode: Bacteria engineered to produce liquid fuel can eat carbon dioxide and hydrogen from solar-powered water-splitting!


(11.2 MB, 12.25 minutes)


Show notes: 
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TWiV 347: Rose rosette and squirrel roulette

Hosts: Vincent RacanielloAlan Dove, and Rich Condit


Vincent, Alan, and Rich discu... Read More

THESE YEAST CELLS SAY ‘HI’ AND OTHERS RESPOND

Scientists have engineered yeast cells that can “talk” to one another using a versatile plant hormone called auxin.

Typically, these simple fungal cells (Saccharomyces cerevisiae) usually do their jobs—making bread rise or converting sugar into alcohol—without having to communicate or work to... Read More

Why West Nile virus is more dangerous in the elderly

West Nile virus (WNV) is particularly dangerous in older people, who account for a large number of severe cases and deaths caused by the virus. WNV infection turns serious when the virus crosses the blood-brain-barrier and wreaks havoc among nerve cells in the brain. A study published on July 23... Read More

It takes a village... to ward off dangerous infections? New microbiome research suggests so

ANN ARBOR, Mich. -- Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests. Read More

Antiviral compound protects nonhuman primates against Marburg virus

An experimental drug that protected monkeys from the deadly Marburg virus appears to have potential for treating people who have been exposed to the virus, according to a study published in the July 23 edition of The New England Journal of Medicine. Marburg virus is closely related to Ebola viru... Read More

TWiM #108: Vaccine in the time of cholera

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 108 Letters

Nervous in San Diego writes:


Dear Professors of TWiM,
I was recently introduced to TWiM by a neighbor. For the last few weeks I have been listening to the backlog of TWiM podcasts, mainly while walking our dog. Regrettably, our dog is a lousy conversationalist. L... Read More

Health-care providers a major contributor to problem of antibiotic overuse

SALT LAKE CITY - 10 percent of health care providers write an antibiotic prescription for nearly every patient (95 percent or more) who walks in with a cold, bronchitis or other acute respiratory infection (ARI), according to a new Centers for Disease Control and Prevention-supported study publi... Read More

Virus-like particle vaccine protects mice from many flu strains

A vaccine that protects against a wide variety of influenza viruses (a so-called universal flu vaccine) is a critical public health goal given the significant rates of illness and death caused by seasonal influenza and the potentially devastating effects of a pandemic influenza strain. Now, rese... Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

Diarrhea in cats

Barbara Hinney and her colleagues from the Institute for Parasitology at the University of Veterinary Medicine, Vienna, screened 298 faecal samples taken from cats across Austria for single-cell intestinal parasites, so called enteric protozoa. The samples came from private households, catteries... Read More

New resource makes gene-editing technology even more user friendly

Researchers at Harvard University and the University of California, San Diego, have developed a new user-friendly resource to accompany the powerful gene editing tool called CRISPR/Cas9, which has been widely adopted to make precise, targeted changes in DNA. This breakthrough has the potential t... Read More

Tiny Ocean Microbes are Brightening Up the Sky

Phytoplankton may be microscopic, but that doesn’t mean we can’t see them. Just look up: These little critters are brightening up cloudy days around the world. Read More

TWiV 346: A double helical career

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler


Guest:&nb... Read More

Burden of dengue, chikungunya in India far worse than understood

New Johns Hopkins Bloomberg School of Public Health research finds new evidence that an extremely high number of people in southern India are exposed to two mosquito-borne viruses -- dengue and chikungunya. Read More

UGA researchers develop breakthrough tools in fight against cryptosporidium

Athens, Ga. - Researchers at the University of Georgia have developed new tools to study and genetically manipulate cryptosporidium, a microscopic parasite that causes the diarrheal disease cryptosporidiosis. Their discoveries, published in the journal Nature, will ultimately help researchers in... Read More

The Arctic fresh water virome

Although we now understand that viruses are the most abundant organisms on Earth, there are gaps in our knowledge about their distribution in different environments. Results of a new study reveal the diversity and distribution of viruses in Arctic fresh waters. Read More
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