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Wolbachia, DNA Methylation, and Cytoplasmic Incompatibility

Wolbachia pipientis is a worldwide bacterial parasite of arthropods that infects germline cells and manipulates host reproduction to increase the ratio of infected females, the transmitting sex of the bacteria. The most common reproductive manipulation, cytoplasmic incompatibility (CI), is expre... Read More

A novel plate based method for screening DOPA / melanin producing bacteria

Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More

Bacteria’s Game of ‘Telephone’ Foils Microbiologists’ Eavesdropping

While human families are easily illustrated as a tree, bacterial families look more like a heap of branches. Scientists are trying to trace the connections between those branches in an effort to learn more about the bacteria that harm us, and those that do not.

UConn’s Peter Gogarten and Joer... Read More

Study May Help Slow the Spread of Flu

An important study conducted in part at the Department of Energy’s SLAC National Accelerator Laboratory may lead to new, more effective vaccines and medicines by revealing detailed information about how a flu antibody binds to a wide variety of flu viruses.

The flu virus infects millions of p... Read More

Viral genomes in 700 year old caribou scat

Recovering viral genomes from ancient specimens can provide information about viral evolution, but not many old nucleic acids have been identified. A study of 700 year old caribou feces reveals that viruses can be protected for long periods of time – under the right conditions. Read More

Who Made That Flavor? Maybe A Genetically Altered Microbe

For practically our whole history of cooking and eating, we've gotten our spices and most flavors (not to mention all of the other basic nutrients that keep us alive) straight from plants.

But researchers and biotech companies are starting to produce some of these nutrients and flavors — espe... Read More

Rapid Ebola Test Is Focus of NIH Grant to Rutgers Scientist

The test would quickly diagnose patients in remote locations where disease spread has been rampant.

Rutgers researcher David Alland, working with the California biotechnology company Cepheid, has received a grant of nearly $640,000 from the National Institutes of Health to develop a rapid tes... Read More

UEA research could revolutionise genomic sequencing of drug-resistant bacteria

New nanopore DNA sequencing technology on a device the size of a USB stick could be used to diagnose infection - according to new research from the University of East Anglia and Public Health England.

Researchers tested the new technology with a complex problem – determining the cause of anti... Read More

Ebola Infections Fewer Than Predicted by Disease Models

A few months ago the U.S. Centers for Disease Control and Prevention predicted that up to 1.4 million people in Liberia and Sierra Leone could become infected with Ebola by mid-January. In a recent address to the Senate, CDC director Tom Frieden said that worst-case scenario would not pan out.
... Read More

Promising compound rapidly eliminates malaria parasite

An international research collaborative has determined that a promising anti-malarial compound tricks the immune system to rapidly destroy red blood cells infected with the malaria parasite but leave healthy cells unharmed. St. Jude Children’s Research Hospital scientists led the study, which ap... Read More

All the microbes of the field will clap their hands

I’ve said it before and I’ll say it again: microbes are everywhere, and everywhere important. As regular readers will know, I’ve recently become obsessed with cultivating our microbial companions to make delicious foods. But you don’t have to have to constantly minding jars of kraut or jugs of m... Read More

Terminal Proteins: Crossing the Border

A variety of Bacteria, Archaea, and mobile genetic elements replicate their DNA as a linear chromosome using terminal proteins (TPs) to prime DNA synthesis, thus solving their end replication problem. As described in an earlier post, phage φ29 uses its TPs to also organize the sites of DNA repli... Read More

BacterioFiles 194 - Squirrel Sequence Stops Similar Sickness

This episode: Remnants of viral infection left behind in squirrels' genome may protect them from incoming viruses!


(9.3 MB, 10.1 minutes)


Show notes: 
Jou... Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.


Host:  Read More

Is HIV Evolving Into A Weaker Virus?

Viruses are masters at mutating.

So the big concern with deadly viruses, like Ebola and hepatitis C, is that they will evolve into more dangerous forms over time.

It looks like just the opposite is happening with HIV — although it's happening slowly.

"HIV can generate any mutation in th... Read More

Resistance and Futility

Scientists reveal how penicillin deals bacteria a devastating blow – work that may lead to new antibiotics.

Penicillin, the wonder drug discovered in 1928, works in ways that are still mysterious almost a century later. One of the oldest and most widely used antibiotics, it attacks enzymes th... Read More

‘Superbugs’ Kill India’s Babies and Pose an Overseas Threat

A deadly epidemic that could have global implications is quietly sweeping India, and among its many victims are tens of thousands of newborns dying because once-miraculous cures no longer work.

These infants are born with bacterial infections that are resistant to most known antibiotics, and ... Read More

A POISONOUS CURE

Take two poisonous mushrooms, and call me in the morning. While no doctor would ever write this prescription, toxic fungi may hold the secrets to tackling deadly diseases.

A team of Michigan State University scientists has discovered an enzyme that is the key to the lethal potency of poisonou... Read More

Pantry Pests Harbor Plastic-Chomping Bacteria

Polyethylene is one of the most popular and, unfortunately, persistent types of plastics. Bags, bottles, and packaging made from the polymer accumulate in landfills and oceans across the globe. Scientists lament that microbes can’t chew up the plastic to render it harmless. However, a new study ... Read More

CDC: Flu shot less effective this year because current virus has mutated

Scientists are concerned about what they're seeing so far this flu season, the director of the Centers for Disease Control and Prevention said Thursday, a day after the agency advised doctors this year's flu vaccine is not as effective because the current strain of the virus has mutated.

Dr. ... Read More
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