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First evidence that GM mosquitoes reduce disease

Releasing genetically modified mosquitoes appears to have helped reduce cases of dengue in a town in Brazil. The news comes as the US is considering whether to approve the use of the same mosquitoes.

The trial involved Aedes mosquitoes that had been modified to kill off wild mosquitoes of the... Read More

Method suitability in microbiology: understanding complex cGMP guidelines

Particularly in the pharmaceutical industry, microbiological method development and, specifically, method suitability is often overlooked or left until the end of a project. However, it is important to give both method suitability and development due consideration as it can be a complicated proc... Read More

Gut bacteria imbalance increases diabetes risk

Currently, scientists think the major contributors to insulin resistance are excess weight and physical inactivity, yet ground-breaking new research by an EU funded European-Chinese team of investigators called MetaHit have discovered that specific imbalances in the gut bacteria can cause insuli... Read More

First known case of female-to-male Zika transmission announced

The first case of female-to-male sexual transmission of the Zika virus has occurred in New York City, the Centers for Disease Control and Prevention announced Friday. Up until now, it was thought that the only likely route of sexual transmission was male-to-female or male-to-male.

The surpris... Read More

One microbial pathogen 'disguised' as another leads to misdiagnoses

If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More

Antibiotic stewardship - a community effort

As we highlighted in our previous blog, antibiotic stewardship – the careful use of appropriate antibiotic administration – can have positive effects. A small change from a difference in clinical lab reporting led to less drug use, which led to fewer drug-resistant infections. When we think of a... Read More

3rd Global Microbiologists Annual Meeting

The organization feels proud and honoured in inviting the contributors across the globe to its premier "3rd Global Microbiologists Annual Meeting" to be held during August 15-17, 2016 at Portland, Oregon, USA.

This year's meeting will showcase the role of microbes in different ecosystems by r... Read More

Largest HIV transmission study conducted

A new study has found that neither gay men nor heterosexual people with HIV transmit the virus to their partner, provided they are on suppressive antiretroviral treatment.



The PARTNER study, which is the world's largest study of people with HIV who have had condomless sex with their HIV ... Read More

Discovery of new strains of the HTLV-4 virus in hunters bitten by gorillas in Gabon

Scientists from the Institut Pasteur and the CNRS have identified two new strains of the HTLV-4 virus in two hunters who were bitten by gorillas in Gabon. These findings, published in the journal Clinical Infectious Diseases, support the notion that gorillas represent a major source of infectiou... Read More

Microbial responses to land management practices

Microbial communities are essential drivers of soil functional processes such as nitrification and heterotrophic respiration. Although there is initial evidence revealing the importance of soil type in shaping microbial communities, there has been no in-depth, comprehensive survey to robustly es... Read More

And now for something completely different: optimistic news from the world of antibiotic stewardship

There’s no way to avoid the news of a growing concern for drug-resistant infections. In both life-threatening and relatively superficial infections, the ability to successfully treat microbial infections with antimicrobials is decreasing. Our only recourse is to use the drugs we have carefully w... Read More

Progress Towards Protection from Highly Lethal Ebola, Marburg Viruses

Washington, DC – July 12, 2016 – Ebola and Marburg filovirus disease outbreaks have typically occurred as isolated events, confined to central Africa. However, the recent Ebola epidemic spread to several African countries, and caused 11,000 deaths. That epidemic underscored the need to develop v... Read More

Self-Prescribing Antibiotics is a Big Problem

Washington, DC – July 11, 2016 - Five percent of adults from a cohort of 400 people reported using antibiotics without a prescription during the previous 12 months. Twenty-five percent said they would use antibiotics without contacting a medical professional. These findings demonstrate yet anoth... Read More

Colistin-Resistant Gene Detected in the U.S. for the Second Time: Investigators Alert to Its Possible Spread

Washington, DC - July 11, 2016 - For the second time, a clinical isolate of a bacterial pathogen has been detected in humans in the United States which carries the colistin resistance gene, mcr-1. This may also be the first case to show up in the US. That would be concerning because plasmids, g... Read More

New Resistance Gene Found in "High Risk" Multidrug-Resistant Pathogen

Washington, DC – July 11, 2016 – A team of Italian investigators has discovered a new variant of an emerging antibiotic resistance mechanism. The new variant, dubbed mcr-1.2, confers resistance to colistin, a last-resort antibiotic against multidrug-resistant Gram-negative pathogens. The researc... Read More

BacterioFiles 259 - Fluke Froth Fosters Fester Fixing

This episode: I converse with Dr. Michael Smout about a liver fluke parasite could help heal chronic wounds more quickly!


(13.4 MB, 14.6 minutes)


Show notes: 
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TWiV 397: Trial by error

Vincent speaks with David Tuller about flaws in the U.K's $8 million PACE trial for chronic fatigue syndrome, and efforts to have the trial data released.


Host: Vincent Racaniello 


Gue... Read More

What does the structure reveal about a colony collapse disorder-associated virus

Colony collapse disorder (CCD) has caused such a profound drop in honeybee populations that even the U.S. Congress is addressing the issue: Senator Jeff Merkley (D-Oregon) has proposed the Pollinator Recovery Act to preserve pollinator habitat. The rapid decline in these important pollinators af... Read More

Zika in Colors

Our work on Zika virus has utilized two different antibodies to detect Zika virus replication within cells. I described one antibody, directed against double-stranded RNA (dsRNA) in a previous article. A second antibody directed against a Zika virus protein has also been useful...

Click "sou... Read More

Diversity and Activity of Communities Inhabiting Plastic Debris in the North Pacific Gyre

Marine plastic debris is a growing concern that has captured the general public’s attention. While the negative impacts of plastic debris on oceanic macrobiota, including mammals and birds, are well documented, little is known about its influence on smaller marine residents, including microbes t... Read More
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