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MWV Episode 94 - TWiM #99: Careers in Biodefense
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HIV strain matters for treating new cases

The specific strain of HIV that a person first contracts can have a lasting impact on how the virus disrupts his or her immune system, say researchers.

“This may have important implications for cure strategies aimed at eliminating the viral reservoir, as individuals infected with low replicat... Read More

First results from Ebola vaccine trial show acceptable safety profile

The first results from a trial of a candidate Ebola vaccine at Oxford University suggest the vaccine has an acceptable safety profile at the doses tested, and is able to generate an immune response.

'The vaccine was well tolerated. Its safety profile is pretty much as we had hoped,' said Prof... Read More

Airport screening misses half of disease cases but could be improved

Scientists have shown that airport screening for disease will often miss half or more of infected travelers, but can be improved by customizing to pathogens. The findings are published in the journal eLife.

They present options for policy makers; for example whether resources would be better ... Read More

Superbug outbreak has killed two at UCLA medical center

This week, doctors at the University of California Los Angeles Medical Center discovered that a contaminated medical tool had been spreading antibiotic-resistant bacteria to patients. The bacteria, known as carbapenem-resistant Enterobacteriaceae or CRE, has been called a “nightmare” bacteria by... Read More

CU neurologist finds link between virus causing chicken pox and giant cell arteritis

A new study developed at the University of Colorado School of Medicine at the Anschutz Medical Campus links the virus that causes chicken pox and shingles to a condition that inflames blood vessels on the temples and scalp in the elderly, called giant cell arteritis.

Giant cell arteritis, whi... Read More

TWiM #98: Bacteria and eukaryotes get horizontal

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 98 Letters

 


Patrick writes:


Hi Vincent,


I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More

First results from an Oxford University trial of an Ebola vaccine (video)

A trial of a GSK/NIH candidate Ebola vaccine at Oxford University suggests the vaccine has an acceptable safety profile and is able to generate an immune response.
Read More

Ancient rocks show life could have flourished on Earth 3.2 billion years ago

The ability to use atmospheric nitrogen to support more widespread life was thought to have appeared roughly 2 billion years ago. Now research from the University of Washington looking at some of the planet’s oldest rocks finds evidence that 3.2 billion years ago, life was already pulling nitrog... Read More

Mutant bacteria that keep on growing

The typical Escherichia coli, the laboratory rat of microbiology, is a tiny 1-2 thousandths of a millimeter long. Now, by blocking cell division, two researchers at Concordia University in Montreal have grown E. coli that stretch three quarters of a millimeter. That's up to 750 times their norma... Read More

Paper Test Quickly Detects Ebola, Dengue, And Yellow Fever

Researchers in the US have developed a silver nanoparticle-based paper test to simultaneously detect dengue, yellow fever and Ebola. This could provide a cheap and reliable diagnosis for all three diseases, that’s as quick as a home pregnancy test.

The test is made from strips of paper contai... Read More

Rust preserves fossils from early Earth

Since life originated on Earth between 3.8 and 3.9 Ga ago, microorganisms have significantly shaped and influenced the chemistry of Earth’s surface and subsurface environments. Reconstructing the evolution of early microbial life depends mainly on finding organic and mineral remnants of microbia... Read More

Measles in the brain: Fusion gone awry

The entry of enveloped viruses into cells begins when the membrane that surrounds these virus particles fuse with a cell membrane. The process of virus-cell fusion must be tightly regulated, to make sure it happens in the right cells. The fusion activity of measles viruses isolated from the brai... Read More

Microbe helps switchgrass 'detox' polluted soil.

Switchgrass successfully removed up to 40 percent of the PCBs from contaminated soils in lab experiments. When a PCB-oxidizing microorganism joined in, the removal rate reached 47 percent.

The researchers investigated how adding an aerobic PCB-oxidizing microorganism could enhance the oxidati... Read More

Canned fruit safer than the frozen variety

Canned fruit is often safer than the frozen variety according to University of NSW Associate Professor Julian Cox, an expert in food microbiology.

"The heat treatment used to make canned products shelf stable in ambient temperatures is much more than sufficient to kill micro-organisms includi... Read More

How a Bacterial Virus Found in Jerusalem Sewage Could Prevent Root Canal Infections

According to the Review on Antimicrobial Resistance commissioned by the UK Prime Minister, failing to address the growing problem of drug-resistant infections could cause 10 million deaths a year and cost up to $100 trillion USD by 2050.

Now, researchers from the Hebrew University of Jerusal... Read More

Bacteria jump between species more easily than previously thought

A new study suggests that bacteria may be able to jump between host species far easier than was previously thought. Researchers discovered that a single genetic mutation in a strain of bacteria infectious to humans enables it jump species to also become infectious to rabbits. The discovery has m... Read More

Johns Hopkins and CDC prepare emergency department staff to care for patients with infectious disease

Four Web-based training modules developed by Johns Hopkins Medicine for emergency department personnel who treat patients with infectious diseases are now available on the Centers for Disease Control and Prevention (CDC) website.

Titled Ebola Preparedness: Emergency Department Guidelines, the... Read More

More infectious diseases emerging because of climate change

The appearance of infectious diseases in new places and new hosts, such as West Nile virus and Ebola, is a predictable result of climate change, says a noted zoologist affiliated with the Harold W. Manter Laboratory of Parasitology at the University of Nebraska-Lincoln.

In an article publishe... Read More

A newly discovered bacterial family may become a weapon in the fight against malaria

A new family of bacteria that are common in malaria mosquitoes has been described by researchers at Swedish University of Agricultural Sciences (SLU) and Uppsala University in Sweden, Justus-Liebig-Universität Giessen, Germany, and the Veterinärmedizinische Universität, Austria. Now, attempts ar... Read More
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