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CRISPR/Cas9 used for rapid functional study of cancer-causing genes

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their ca... Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

Multi-tasking Flu Vaccine Could Provide Better Protection against Outbreaks

Washington, D.C.—October 27, 2015—Australian researchers have found a way to boost the effectiveness and cross-protective capabilities of an influenza A vaccine by adding a simple component. Published this week in mBio, an online open-access journal of the American Society for Microbiology, the ... Read More

American Society for Microbiology designates Ocean Station ALOHA as a Milestones in Microbiology site

Washington, DC – October 27, 2015 – Ocean Station Aloha, University of Hawai‘i at Mānoa (UHM) has been designated a Milestones in Microbiology site by the American Society for Microbiology. Read More

Social yeast cells prefer to work with close relatives to make our beer, bread and wine

Baker's yeast cells living together in communities help feed each other, but leave incomers from the same species to die from starvation, according to new research from the University of Cambridge. Read More

SOME CORAL-ALGAE COMBOS CAN HANDLE CLIMATE CHANGE

For some time, scientists have known that certain combinations of coral and algal species were more tolerant to temperature extremes than others, and therefore more likely to survive in the changing conditions predicted for the future. Read More

DISCOVERY MAY LEAD TO VACCINE FOR BIRTH DEFECT VIRUS

Scientists believe they may be a step closer to developing a vaccine for congenital cytomegalovirus (CMV), one of the world’s leading infectious causes of birth defects. Read More

DRUG FROM BANANAS MAY FIGHT FLU VIRUS

Bananas contain a substance that, when changed slightly by scientists, shows promise to fight a wide range of viruses, including the flu. Read More

BacterioFiles 235 - Dust DNA Detectives with Dr. Dunn

This episode: I talk with Dr. Rob Dunn about his team's research into determining where a dust sample comes from based on the microbes present in it!


(12.6 MB, 13.7 minutes)


Show notes: 
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TWiV 360: From Southeastern Michigan

Hosts: Vincent Racaniello and Kathy Spindler


Guests:  Read More

MWV 98 - TWiM #113 Waves of Change


Vincent meets up with Romney Humphries and Duncan MacCannell at the 79th annual meeting of the Southern California branch of the American Society f... Read More

Bacteriophage Treatment Decontaminates Infant Formula

Washington, DC – October 23, 2015 - A phage showed strong anti-microbial activity against a type of food-borne bacterium that often kills infants after infecting them via infant formula. Phages are viruses that infect only bacteria. The research is published October 23 online in Applied and Envi... Read More

Plague infected humans much earlier than previously thought

Plague infections were common in humans 3,300 years earlier than the historical record suggests, reports a study published October 22 in Cell. By sequencing the DNA of tooth samples from Bronze Age individuals from Europe and Asia, the researchers discovered evidence of plague infections roughly... Read More

ANTIBIOTICS DON’T POP BACTERIA LIKE A BALLOON

The days when antibiotics worked reliably and scientists could assume they worked directly—like popping a balloon—are fading. As resistance mounts, understanding how antibiotics really work could be the key to sustaining their efficacy. Read More

TWiM #113: Waves of Change

Host: Vincent Racaniello


Special guests: Romney Humphries and Read More

New gene a key to fighting sepsis

Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis. Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

BacterioFiles 234 - Phone, Floor Phylum Forensics

This episode: Learning things about people's identity and movements from microbial communities on their phones and shoes!


(5.4 MB, 5.8 minutes)


Show notes: 
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TWiV 359: A Blossom by any other name

Host: Vincent Racaniello


Guest: Blossom Damania


Vincent speaks with Blossom about he... Read More

TWiP 97 letters

Jerry writes:


Scabies


Nancy writes:


Scabies.
I mean, Scabies?
I hope the gentleman contracted them via a freshly contaminated, unlaundered hand towel.


Thank you for all you do, guys.


Nancy


Steve writes... Read More

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