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Culture-independent discovery of new archaeal virus

What kinds of microbes do you associate with hot springs? Maybe microbial mats? Thermus aquaticus and the discovery of Taq polymerase? Archaea, previously (and erroneously) thought to be strict extremophiles? Viruses may not be the first microbial subtype that springs to mind (pun intended) but ... Read More

Antibiotics for appendicitis -- yes and no

Surgery has been the standard treatment for appendicitis for more than a century. Millions of appendectomies are performed annually in the world, more than 300,000 in the US alone. Studies have been carried out over the years to determine whether non-perforated appendicitis could be treated with... Read More

Immune study shows how gut keeps deadly infections at bay

Treatment and prevention of life-threatening infections could be improved by research that reveals how bacteria are kept in check.

Researchers have discovered how the immune system stops bacteria in our gut from leaking into the blood stream and causing body-wide inflammation, such as sepsis.... Read More

Researchers hope hybrid compounds can sensitize and inhibit malaria parasites in one blow

Because of its safety, efficacy, and affordability, chloroquine remains the treatment of choice for all Plasmodium species, except in regions with chloroquine-resistant P. falciparum. Chloroquine-resistant protists are treated with combination therapy, which includes artemisinin-derived molecule... Read More

Potential Zika virus risk estimated for 50 US cities

BOULDER - Key factors that can combine to produce a Zika virus outbreak are expected to be present in a number of U.S. cities during peak summer months, new research shows. Read More

Experimental dengue vaccine protects all recipients in virus challenge study

A clinical trial in which volunteers were infected with dengue virus six months after receiving either an experimental dengue vaccine developed by scientists from the National Institutes of Health (NIH) or a placebo injection yielded starkly contrasting results. All 21 volunteers who received th... Read More

Preclinical Studies on the Pharmacokinetics, Safety, and Toxicology of Oxfendazole: Toward First in Human Studies

A number of BZ anthelmintics used in veterinary medicine have been considered for transition to human use, including oxibendazole and oxfendazole (OXF). In addition, flubendazole, already approved for use as an intestinal anthelmintic, is also being developed as a treatment against adult filaria... Read More

Microbial communication over the airwaves

Jean-Paul Latgé originally wanted to know if he could test the breath of patients with Aspergillus infections for volatile compounds produced by the fungus. His group at the Pasteur Institute in Paris thought this might be a new way of diagnosing fungal culprits like Aspergillus fumigatus that o... Read More

Mismatched expectations most common reason for patients not completing HPV vaccine series

BOSTON-- Conflicting expectations between parents and medical providers about who is responsible for scheduling follow-up appointments is resulting in a failure of young girls completing the Human Papilloma Virus (HPV) vaccination series, according to a new study led by Boston Medical Center res... Read More

New SARS-like virus is poised to infect humans

The new virus, known as WIV1-CoV, directly binds to the same human receptor as the SARS strain that infected thousands in 2002 Read More

Agar Art 2016 Contest Submit by May 6

We hope you've started plating your dishes! Here are some of the 2016 entries thus far. Show us your creative streaking! For contest entry rules visit: www.microbeworl.org/art. Submissions close May 6, 2016 11:59 P.M.EST.Entries pictured from left to right: Symbol of ASM, A Once in a Lifetime Ki... Read More

Zika virus infection of the nervous system

Evidence is mounting that Zika virus is neurotropic (able to infect cells of the nervous system) and neurovirulent (causes disease of the nervous system) in humans. Read More

Moving beyond metagenomics to find the next pandemic virus

I was asked to write a commentary for the Proceedings of the National Academy of Sciences to accompany an article entitled SARS-like WIV1-CoV poised for human emergence. I’d like to explain why I wrote it and why I spent the last five paragraphs railing against regulating gain-of-function experi... Read More

BacterioFiles 243 - Fungal Friends Facilitate Phytoextraction (feat. Cat Adams)

This episode: A conversation with Cat Adams about how fungi help plants clean up toxic zinc nanoparticles in soil!


(14.6 MB, 16 minutes)


Show notes: 
Read More

TWiV 380: Viruses visible in le microscope photonique

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiP 105: Survival of the fattest

The TWiPanosomes solve the case of the Young Man from Anchorage, and discuss how cestode parasites increase the resistance of brine shrimp to arsenic toxicity.


Hosts: Vincent Racaniello Read More

New drug class offers potential new treatment for lethal bacteria

A new class of drugs has shown promise for treating the bacteria that cause legionnaires' disease, a potentially fatal lung infection. Read More

UNC School of Medicine researchers prove HIV targets tissue macrophages

CHAPEL HILL, N.C. - Investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have clearly demonstrated that HIV infects and reproduces in macrophages, large white blood cells found in the liver, brain and connective tissues of the body. This dis... Read More

Urinary tract infection: How bacteria nestle in

Almost every second woman suffers from a bladder infection at some point in her life. Also men are affected by cystitis, though less frequently. In eighty percent of the cases, it is caused by the intestinal bacterium E. coli. It travels along the urethra to the bladder where it triggers painful... Read More

Bid to beat baby chest infection boosted by immune study

Babies at risk of a serious lung infection could be helped by a therapy based on the body's natural immune defences. Read More
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