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Immune system maintains a memory of past infections by priming genes for future encounters

Our ability to fight off recurrent infections, such as colds or flu, may lie in the 'immunological memory' found in a newly discovered class of gene regulatory elements, according to research from the University of Birmingham, supported by the BBSRC and Bloodwise. Read More

Chickenpox, shingles vaccine may cause corneal inflammation in some patients

COLUMBIA, Mo. (Jan. 20, 2016) -- In use for more than 20 years, the varicella zoster virus vaccine for chickenpox and shingles is considered an essential medicine by the World Health Organization (WHO). However, researchers from the University of Missouri School of Medicine have found, in rare i... Read More

Fewer than 1 in 5 nurses comply with guidelines for standard precautions

Washington, Jan. 20, 2016 - Only 17.4 percent of ambulatory care nurses reported compliance in all nine standard precautions for infection prevention, according to a study published in the January issue of the American Journal of Infection Control, the official publication of the Association for... Read More

Whole-genome sequencing can help ID hospital outbreaks

Drug-resistant infections are becoming one of the scariest epidemics since the advent of antibiotic discovery. Although microbes like methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Klebsiella pneumoniae, and multidrug-resistant Pseudomonas aeruginosa are responsible for... Read More

Estrogen protective against flu virus in women but not men, study suggests

Estrogen dramatically reduced the amount of flu virus that replicated in infected cells from women but not from men, a new study by researchers at the Johns Hopkins Bloomberg School of Public Health shows. Read More

Infant-friendly flu vaccine developed with key protein

According to the World Health Organization, influenza causes serious illness among millions of people each year, resulting in 250,000 to 500,000 deaths. Those most at risk include infants younger than six months, because they cannot be vaccinated against the disease. Now, researchers at the Univ... Read More

TWiV 372: Latent viral tendencies

Hosts: Vincent RacanielloAlan DoveRich Condit Read More

TWiM #119: Power of one

Hosts: Vincent RacanielloMichael Schmidt, and Read More

TWiM 119 Letters

Jeanne writes:


Dear TWiM,
 
With regard to the question about culturing gut microbes from Drosophila:
 
I was lucky enough to take a sabbatical in the lab of Dr. Angela Douglas (http://angeladouglasl... Read More

Toward development of microarrays to test water safety

Imagine taking an ocean-side vacation, with the sun, sand, and water lulling you to relaxed bliss. After day at the beach, you experience an intense bout of stomach cramps and – more delicately put – GI distress. A rare day off is ruined because of a bug you picked up. Next, imagine a situation ... Read More

The switch from trivalent to bivalent oral poliovirus vaccine: Will it lead to polio?

In four months, 155 countries will together switch from using trivalent to bivalent oral poliovirus vaccine. Will this change lead to more cases of poliomyelitis? Read More

Scientists uncover how part of a protein helps primates fight HIV

London, January 14, 2016 - Scientists have uncovered part of a protein found in humans and other primates that can help us fight off HIV. In a new study published in the journal Heliyon, researchers discover how this structure can stop HIV from working and switch on our immune system at the same... Read More

How malaria fools our immune system

Okinawa Institute of Science and Technology Graduate University (OIST) reconstructed the 3D structure of one of the proteins of Plasmodium falciparum, the causative agent of malaria and the antibodies that act as the first line of defense against the parasite. This research, published in Cell Re... Read More

MdlM116: La importancia de los virus como patógenos emergentes en América Latina

Los virus son considerados por la mayoría como patógenos en todo tipo de entidades biológicas.  Sin embargo la gran mayoría de los virus son inocuos a sus células hospedero.  Nuestro invitado de hoy, el Dr. Paolo Zanotto es investigador y profesor en la Universidad de Sao Paolo, Bra... Read More

Azithromycin During Delivery: Weighing Benefits and Costs

Washington, DC – January 13, 2016 - Some infants of lactating mothers given the antibiotic and antimalarial, azithromycin, during delivery may be protected from disease, or harmed by the drug. These findings are the results of the most comprehensive evaluation of the transfer of azithromycin int... Read More

Experimental immunotherapy zaps 2 most lethal Ebola virus strains

January 13, 2016--(BRONX, NY)--Researchers at Albert Einstein College of Medicine and the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) have engineered the first antibodies that can potently neutralize the two deadliest strains of the virus that causes Ebola hemorrhagic ... Read More

Why do some infections persist? Blame bacterial socialism, says new study

New research to be published January 13 in the journal Scientific Reports shows that some bacterial cultures adopt an all-for-one/one-for-all strategy that would make a socialist proud in preparing for the possibility of an antibiotic onslaught. Read More

New promise for treatment of enterovirus infection

Feeling a bit under the weather? There’s a decent chance you’re suffering from an infection with an enterovirus. Enteroviruses are a commonly encountered virus, especially in the summer and fall. They can cause a variety of symptoms, from cold-like symptoms such as runny nose or fever to more se... Read More

Innate immune defenses triggered by unsuspected mechanism

To the amazement of researchers in immunology and genetics, a previously unsuspected mechanism is activated in the presence of pathogens after only a few hours. "In the hours following an attack by bacteria, we observed the activation of thousand of genes in the cells of the innate immune system... Read More

The Institut Pasteur in French Guiana publishes the first complete genome sequence of the Zika virus

Having confirmed the first cases of infection in Suriname then in French Guiana, the Institut Pasteur in French Guiana has sequenced the complete genome of the Zika virus, which is responsible for an unprecedented epidemic currently sweeping through the tropical regions of the Americas. Publishe... Read More

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