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New Compound for Alcoholism Treatment

BOC Sciences-A new beta-carboline compound shows great potential for alcoholism treatment. At present, no side effects caused by the new compound have been found in the trials on rats. The compound was developed by research team from Wisconsin in Milwaukee, US. With further successful tests and ... Read More

Statistical advances help unlock mysteries of the human microbiome

Advances in the field of statistics are helping to unlock the mysteries of the human microbiome--the vast collection of microorganisms living in and on the bodies of humans, said Katherine Pollard, a statistician and biome expert, during a session today at the 2015 Joint Statistical Meetings (JS... Read More

NIH-funded study establishes genomic data set on Lassa virus

An international team of researchers has developed the largest genomic data set in the world on Lassa virus (LASV). The new genomic catalog contains nearly 200 viral genomes collected from patient samples in Sierra Leone and Nigeria, as well as field samples from the major animal reservoir, or h... Read More

BacterioFiles 226 - Deep Dwellers Diversify

This episode: Archaea living in the deep ocean (and their viruses) have clever ways to maintain diversity and adaptability!

(10.3 MB, 11.25 minutes)

Show notes: 
Read More

Breastfeeding May Bring Children with More Risk for Toxic Chemicals

BOC Sciences-It has been long considered that breastfeeding would much better than formula milk in various aspects like the variety of nutrition and etc. However recent research found that breastfeeding may expose children to a series of industrial chemical substances that can pose harm to the i... Read More

TWiV 351: The dengue code

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distan... Read More

Study: Breastfeeding could reduce common infections among Indigenous infants

TORONTO, Aug. 17, 2015--Promoting breastfeeding could lead to a substantial reduction in common infections and even deaths that are more common in Indigenous infants than non-Indigenous infants, a new study suggests. Read More

Cells in Senescence State May Help Slow down Aging and Cancer Treatment

BOC Sciences-Senescence means a state where cells stop further development in their function but clean themselves and remove the extra substance. Scientists found that when cells go into this stage, the growth rate of tumor would slow down, which is true of aging. The finding was made on the lev... Read More

Long Distance Travelers Likely Contributing to Antibiotic Resistance's Spread

Washington, DC – August 20, 2015 - Swedish exchange students who studied in India and in central Africa returned from their sojourns with an increased diversity of antibiotic resistance genes in their gut microbiomes. The research is published 10 August in Antimicrobial Agents and Chemotherapy, ... Read More

Synthetic DNA vaccine against MERS induces immunity in animal study

PHILADELPHIA - A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. Read More

Expression of a single gene lets scientists easily grow hepatitis C virus in the lab

Worldwide, 185 million people have chronic hepatitis C. Since the late 1980s, when scientists discovered the virus that causes the infection, they have struggled to find ways to grow it in human cells in the lab -- an essential part of learning how the virus works and developing new effective tr... Read More

TWiM #110: Exploring unseen life with unpronounceable words

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 110 Letters

Trudy writes:

I'm sorry, I may have missed something, but the mechanism behind an effective vaccine is still unclear to me, since infection with F. tularensis does not confer protection. How would a vaccine work?

Katy Bosio replies:

In... Read More

MdlM113: Microorganismos Halofilos Extremos y los virus que las infectan con Josefa Anton

Ambientes extremos: salares del mundo, su microbiota y los virus presentes. Estos son los temas a discutirse en el episodio de hoy de La Radio el Mundo de los Microbios. Nuestra invitada la Dra. Josefa (Pepa) Anton, Profesora Titular de Microbiología de la Universidad de Alicante co... Read More

What's lurking in your lungs? Surprising findings emerge from U-M microbiome research

ANN ARBOR, Mich. -- With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Read More

Toilet waste provides knowledge about diseases' global transmission routes

Current international disease surveillance systems are mainly based on reports made by doctors after treatment of infected patients. As a consequence, disease-causing microorganisms and resistance bacteria have time to spread and make large population groups sick before they are detected. Read More

Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes

Link: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002226

Groundbreaking research on the universality and diversity of microorganisms is now challenging the life sciences to upgrade fundamental theories that once seemed untouchable. To fully appreciate the change that... Read More

Following Maternal Transmission, Group B Strep Mutates to Sicken Infants

Washington, DC - August 18, 2015 - Group B streptococcus, a mostly benign inhabitant of healthy adults, is one of the world’s leading causes of neonatal sepsis and meningitis. A team of French investigators has now shown that such cases might occur when the microbe mutates within the infant foll... Read More
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