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Human Disease Modeled in an Organ-On-A-Chip; 'Lung-On-A-Chip' Sets Stage for Next Wave of Research to Replace Animal Testing

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Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have mimicked pulmonary edema in a microchip lined by living human cells, as reported November 7 in the journal Science Translation Medicine. They used this "lung-on-a-chip" to study drug toxicity and identify potential new therapies to prevent this life-threatening condition.

The study offers further proof-of-concept that human "organs-on-chips" hold tremendous potential to replace traditional approaches to drug discovery and development.

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