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Virus exploitscellular waste disposal system

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ETH Zurich researchers demonstrate how vaccinia virus manipulates the cellular waste-disposal system and thereby cleverly tricks the cell into assisting the intruders replication. Now, the virologists have turned the tables, using inhibitors of this cellular waste-disposal system as a way to block virus infection.

Over the years, researchers in the laboratory of ETH-professor Ari Helenius have elucidated the tricks and tactics viruses use to enter human cells and exploit them for their own multiplication and spread. Jason Mercer, senior researcher in the Helenius lab at the Institute of Biochemistry is quite excited about his latest publication. In a collaboration with Berend Snijder and colleagues from the Universtiy of Zürich they have just released a publication which puts forward new insights into how viruses enter human cells.

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