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Teaching E. coli to Endocytose

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What if I told you that engineering a single protein into E. coli is sufficient to make it fill up with membrane-bound vesicles? Would you send me to the couch or to a padded cell? Not so fast, as this is precisely what a group of sixteen investigators from three continents have recently shown by expressing caveolin-1 in E. coli. Caveolin-1 is the main protein involved in the formation of mammalian membrane structures called caveolae. The consequences were amazing.

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