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Synthetic stool a prospective treatment for C. difficile

A synthetic mixture of intestinal bacteria could one day replace stool transplants as a treatment for Clostridium difficile (C. difficile). C . difficile is a toxin-producing bacteria that can overpopulate the colon when antibiotics eradicate other, naturally protective bacteria living there.

“A synthetic stool transplant has a lot of potential because we can control what goes in and we can alter, change, or modify it as necessary,” says Elaine Petrof, an assistant professor in the Department of Medicine at Queen’s University and in the Gastrointestinal Disease Research Unit (GIDRU) at Kingston General Hospital.

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