MicrobeWorld

Appendicitis is an extremely painful and potentially life-threatening condition. The appendix, a fingerlike pouch attached to the large intestine, can sometimes get clogged, causing it to swell with bacteria and burst if it isn't removed in time. Surgery to remove the appendix has been the standard course of treatment since 1889.

It's a relatively simple operation, and one that Lobo says has "been the bread-and-butter operation for most surgical trainees."

But he and his team of researchers at the Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit wanted to know how well antibiotics might work as an initial treatment.

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