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Yale Nobel laureate creates compound that halts growth of malaria parasite

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A drug candidate that has shown promise for neutralizing dangerous bacteria also prevents growth of the parasite that causes malaria, new research by a Yale University team headed by Nobel laureate Sidney Altman shows.

The compound created in the labs of Altman and co-senior author Choukri Ben Mamoun at the Yale School of Medicine penetrates red blood cells and targets molecular machinery that enables the parasite to grow within the cells, according to findings published the week of April 2 in the Proceedings of the National Academy of Sciences.

Altman’s lab has already shown this compound can kill dangerous strains of bacteria and is currently investigating its efficacy in combating infections in skin wounds.

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