A recent study published in PLoS ONE demonstrates the ability to track the distribution of 'dyed' viral particles in vivo, in real-time through combining a mouse model with a labeled adenovirus vector - emitting light in the near-infrared range. They analyse the location of virions following systemic injection and assay its whereabouts in different organs and tissues. The group hopes this will aid in the development of novel, safer and ultimately more effective oncolytic vectors but this approach could be used for many virological or microbiological research questions in myriad model systems.
