Scientists have developed a new way to identify the hidden genetic material responsible for complex traits. The breakthrough ultimately could lead to a deeper understanding of how multiple genes interact to produce everything from blue eyes to blood pressure problems.
The approach allows the Princeton University team to study millions of yeast cells at the same time and to identify regions of the genome that cause a specific trait in the offspring of two yeast strains that have been mated. In using such a large group, the scientists have been able to identify subtle patterns that could not be detected before. The findings are reported in the April 15 edition of Nature.