MicrobeWorld App

appsquarebannerad200x200

ASM Fellowships

Fellowship

Microbes After Hours

Watter-Supply-200x200-Banner

Click for more "Microbes After Hours" videos

Join MicrobeWorld

Subscribe via Email

subscribe

Featured Image

Featured Video

Ebola Virus explained

Supporters

ASM House 200X200

Synthetic Biology: Engineered Bacteria

Researchers have devised a way to attach sugars to proteins using unique biological and chemical methods. This means that large quantities of different glycoproteins can be generated for various medical and biological studies.

The E. coli bacterium produces a protein to which a sugar is attached using an engineered glycosylation machinery. Outside the cell, enzymes trim off the monosaccharide. Other chemically synthesized sugars are then attached. (Diagram: F. Schwarz / ETH Zurich)

When the intestinal bacterium E. coli and the diarrheal pathogen Campylobacter work together, it does not have to result in serious illness. Rather, when biologists and chemists team to use the product of this bacterial collaboration, it opens up a whole new technology with potential pharmaceutical applications. Now, the PhD student Flavio Schwarz from Professor Markus Aebi's group at the Institute of Microbiology of ETH-Zurich and researchers from the University of Maryland have developed a new method for producing glycoproteins.
 
 

Comments (0)

Collections (0)

 

American Society for Microbiology
2012 1752 N Street, N.W. • Washington, DC 20036-2904 • (202) 737-3600
American Society For Microbiology © 2014   |   Privacy Policy   |   Terms of Use