TWiV 179: Was ist ein Virus?

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Created on Sunday, 15 April 2012 18:46

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Gertrud Radu

Gertrud joins the TWiVoners to review how dengue virus infection of mosquitoes alters blood feeding behavior, and gene therapy as practiced by parasitoid wasps.

Right-click to download TWiV 179 (76 MB .mp3, 105 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Renato Dulbecco, 1914-2012 (virology blog)
• William Jarrett, 83 (thanks, Lynn Enquist)
• Dengue virus infection of mosquitoes alters their behavior (PLoS Path)
• Does dengue make mosquitoes thirstier for blood? (NY Times)
• Polydnaviruses of braconid wasps (Science)
• Making nice with viruses (Science)
• Viral and wasp genes involved in symbiotic replication (J Virol)
• Amazing parasitic wasp images
• The Far Side cartoon on mosquitoes (gif)
• TWiV on Facebook
• Letters read on TWiV 179

Weekly Science Picks

Listener Pick of the Week

Ricardo - Evolution: The Natural History of Animal Skeletons
Peter - Self-assembly line (YouTube)

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 178: T-Sharp on how tequila mosquito

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Created on Sunday, 08 April 2012 15:50

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Tyler Sharp

The TWiValians meet up with Tyler Sharp for a discussion on the Epidemic Intelligence Service and controlling dengue.

Right-click to download TWiV 178 (72 MB .mp3, 99 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• 2010 dengue epidemic in Puerto Rico
• Marshall Islands dengue outbreak (one and two)
• Photo of Tyler by Loren Rodgers
• TWiV shout-out by NPR and CIDRAP
• NSABB reverses decision on H5N1 publication
• TWiV on Facebook
• Letters read on TWiV 178

Weekly Science Picks

Listener Pick of the Week

Sasha - Microfluidic Future
Adam - The Conversation
Jim -  ENIAC Programmers Project

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 177: Live in Dublin

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Created on Sunday, 01 April 2012 13:43

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Connor Bamford, Wendy Barclay, Richard Elliott, and Ron Fouchier

A discussion of avian influenza H5N1 transmission experiments in ferrets and novel bunyaviruses at the 2012 Spring Conference of the Society for General Microbiology in Dublin, Ireland.

Right-click to download TWiV 177 (47 MB .mp3, 66 minutes). Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Restricted data on H5N1 transmission (Science)
• Novel bunyavirus in China (NEJM and TWiV 127)
• Ten things about Schmallenberg virus (Microbiology Bytes)
• NSABB reverses decision on H5N1 papers (virology blog)
• TWiV on Facebook
• Letters read on TWiV 177
• Video of this episode - view below or download:
  iPod/iPhone (768 megs | .m4v)
  Apple TV (768 megs | .m4v)
  DivX (X megs | .divx) coming soon
  WMV (X megs | .wmv) coming soon
  MPEG-4 (X megs | .mp4) coming soon

Weekly Science Picks

Connor - Wellcome Trust Science Writing Prize 2012
Vincent - Thoughts on academic scientists giving media interviews

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 176: Ave magi, virorum!

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Created on Sunday, 25 March 2012 18:49

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich answer listener email about MS, CFS, EBV, B cells, virii, influenza B, scientific papers, and more.

Right-click to download TWiV 176 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• More than one way to skin a virus (comments)
• Aerobie aeropress
• Papers software
• Vaccinia movies (one and two)
• Lloyd Kozloff dies
• BSL4 facilities
• TWiV on Facebook
• Letters read on TWiV 176

Weekly Science Picks

Rich - Alan Alda's Flame Challenge (NY Times article, Science editorial)
Alan - ChronoZoom
Vincent - Academic Publishing is Broken by Michael P. Taylor

Listener Pick of the Week

Joel - Fighting a dengue outbreak by Tyler M. Sharp (parts one and two)
Sven-Urban - Fooled by Randomness and The Black Swan by Nassim Nicholas Taleb

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV Live in Dublin, Ireland, Monday, March 26 2012

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Created on Tuesday, 20 March 2012 17:44

Written by ccondayan

Join Vincent Racaniello and guests Connor Bamford, Ron Fouchier, Wendy Barclay and Richard Elliott, for a live-streaming episode of This Week in Virology from the Society for General Microbiology 2012 Spring Conference in Dublin, Ireland. The live stream starts at 3:30 PM GMT (10:30 AM EST | 7:30 AM PST) and you can watch it below. If you have any questions for Vincent or his guests during the broadcast you can tweet your question using the #TWiV hash tag.

In addition, Vincent Racaniello will be accepting the Peter Wildy Prize for Microbiology Education, awarded annually by the Society for General Microbiology for an outstanding contribution to microbiology education. Racaniello's acceptance speech will also be live streamed at 5:15 PM GMT (12:15 PM EST | 9:15 AM PST).

If you live elsewhere in the world, please use www.everytimezone.com, to calculate when the live streams will start in your area.

TWiV 175: More than one way to skin a virus

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Created on Monday, 19 March 2012 00:04

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, and Matt Frieman

Vincent, Alan, and Matt discuss herpes simplex encephalitis in children with innate immune deficiency, and the local response to microneedle-based influenza skin immunization.

Right-click to download TWiV 175 (57 MB .mp3, 80 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Herpes encephalitis in children with TRIF deficiency (J Clin Inv)
• Toll-like receptor and cytosolic pattern recognition receptors
• Skin responses to influenza microneedle vaccine (mBio)
• Microneedles
• Fluzone intradermal influenza vaccine
• QDot nanocrystal technology
• TWiV on Facebook
• Letters read on TWiV 175

Weekly Science Picks

Matt - Phage and the Origins of Molecular Biology
Alan - Digital Imagine Institute
Vincent - iPad apps Goodreader and Notability

Listener Pick of the Week

Jane -Smoking Ears and Screaming Teeth by Trevor Norton

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 174: Dog runs and mooing miRs

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Created on Sunday, 11 March 2012 16:15

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich consider whether pet dogs might transmit human noroviruses, and an RNA virus microRNA that might be involved in oncogenesis.

Right-click to download TWiV 174 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Do pet dogs transmit human norovirus? (J Clin Virol)
• RNA virus miRNA that mimics oncomiR (PNAS)
• MicroRNA expression by an RNA virus (PNAS)
• Lab safety stickers jpg (thanks, Jon!)
• Amateur virologists (Zimmer, NY Times)
• Genome at home (Wired)
• Barbergators sing national anthem (YouTube)
• TWiV on Facebook
• Letters read on TWiV 174

Weekly Science Picks

Rich - NOAA Buoy Data
Alan - Autism's False Prophets by Paul Offit
Vincent - Media Mining

Listener Pick of the Week
Mark - How the West fueled the AIDS epidemic
Henry - Regenesis
Rick - Biopunk: DIY scientists hack the software of life by Marcus Wohlsen

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 173: Going to bat for flu research

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Created on Sunday, 04 March 2012 22:15

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Michael Walsh, and Ashlee Bennett

The TWiVites discuss seroevidence for human infection with avian influenza H5N1, and the discovery of a new influenza virus in Guatemalan bats.

Right-click to download TWiV 173 (85 MB .mp3, 117 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Seroevidence for human H5N1 infection (Science)
• Mammalian-transmissible H5N1 (mBio)
• New information about ferret-adapted H5N1 (NY Times, virology blog)
• New influenza virus from fruit bats (PNAS)
• Elsevier abandons open access assault (The Scientist)
• Le virus le plus dangereux?
• TWiV on Facebook
• Letters read on TWiV 173

Weekly Science Picks

Ashlee - AskScience (Reddit)
Michael - HealthMap (iPhone and Android app)
Rich - H5N1 research discussion at ASMBiodefense
Alan - El Yunque National Forest
Vincent - The Journal of Global Health

Listener Pick of the Week

Judi - NSF visualization challenge

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 172: Two can be as bad as one

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Created on Monday, 27 February 2012 00:10

Written by Vincent Racaniello

Hosts: Vincent Racaniello and Kathy Spindler

Vincent and Kathy discuss how a virus may cause disease distant from its replication site, then review a day in the life of a senior microbiology professor.

Right-click to download TWiV 172 (74 MB .mp3, 102 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Celsius vs Centigrade
• Neuropathogenesis during polymicrobial infection (PLoS Pathogens)
• Tetramer staining (pdf)
• One
• TWiV on Facebook
• Letters read on TWiV 172

Weekly Science Picks

Kathy - Science prize for inquiry-based instruction (Alberts editorial, second winner)
Vincent - The long and winding road to a Ph.D.

Listener Pick of the Week

Greg - Correlation

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 171: One is the loneliest number

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Created on Sunday, 19 February 2012 16:14

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Matt Frieman

Matt joins the TWiVarians to review virus production in single cells and single virion genomics.

Right-click to download TWiV 171 (67 MB .mp3, 92 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• H5N1 results will be published (NY Times)
• Virus production in single cells then and now
• Single virion genomics (PLoS One)
• Multiple displacement amplification (Wikipedia)
• Ranavirus killing turtles, tadpoles in Maryland (Washington Post)
• Three Dog Night
• TWiV on Facebook
• Letters read on TWiV 171

Weekly Science Picks

Matt - H5N1 research discussion
Dickson - The Golden Wand of Medicine by Walter J. Friedlander
Alan - Imagine Science Films
Vincent - E. coli: Good, Bad, and Deadly

Listener Pick of the Week

Daniel - The scale of the Universe
Stefan - A Legacy of Achievement

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.