TWiV Live in Dublin, Ireland, Monday, March 26 2012

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Created on Tuesday, 20 March 2012 17:44

Written by ccondayan

Join Vincent Racaniello and guests Connor Bamford, Ron Fouchier, Wendy Barclay and Richard Elliott, for a live-streaming episode of This Week in Virology from the Society for General Microbiology 2012 Spring Conference in Dublin, Ireland. The live stream starts at 3:30 PM GMT (10:30 AM EST | 7:30 AM PST) and you can watch it below. If you have any questions for Vincent or his guests during the broadcast you can tweet your question using the #TWiV hash tag.

In addition, Vincent Racaniello will be accepting the Peter Wildy Prize for Microbiology Education, awarded annually by the Society for General Microbiology for an outstanding contribution to microbiology education. Racaniello's acceptance speech will also be live streamed at 5:15 PM GMT (12:15 PM EST | 9:15 AM PST).

If you live elsewhere in the world, please use www.everytimezone.com, to calculate when the live streams will start in your area.

TWiV 175: More than one way to skin a virus

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Created on Monday, 19 March 2012 00:04

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, and Matt Frieman

Vincent, Alan, and Matt discuss herpes simplex encephalitis in children with innate immune deficiency, and the local response to microneedle-based influenza skin immunization.

Right-click to download TWiV 175 (57 MB .mp3, 80 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Herpes encephalitis in children with TRIF deficiency (J Clin Inv)
• Toll-like receptor and cytosolic pattern recognition receptors
• Skin responses to influenza microneedle vaccine (mBio)
• Microneedles
• Fluzone intradermal influenza vaccine
• QDot nanocrystal technology
• TWiV on Facebook
• Letters read on TWiV 175

Weekly Science Picks

Matt - Phage and the Origins of Molecular Biology
Alan - Digital Imagine Institute
Vincent - iPad apps Goodreader and Notability

Listener Pick of the Week

Jane -Smoking Ears and Screaming Teeth by Trevor Norton

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 174: Dog runs and mooing miRs

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Created on Sunday, 11 March 2012 16:15

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Vincent, Alan, and Rich consider whether pet dogs might transmit human noroviruses, and an RNA virus microRNA that might be involved in oncogenesis.

Right-click to download TWiV 174 (62 MB .mp3, 86 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Do pet dogs transmit human norovirus? (J Clin Virol)
• RNA virus miRNA that mimics oncomiR (PNAS)
• MicroRNA expression by an RNA virus (PNAS)
• Lab safety stickers jpg (thanks, Jon!)
• Amateur virologists (Zimmer, NY Times)
• Genome at home (Wired)
• Barbergators sing national anthem (YouTube)
• TWiV on Facebook
• Letters read on TWiV 174

Weekly Science Picks

Rich - NOAA Buoy Data
Alan - Autism's False Prophets by Paul Offit
Vincent - Media Mining

Listener Pick of the Week
Mark - How the West fueled the AIDS epidemic
Henry - Regenesis
Rick - Biopunk: DIY scientists hack the software of life by Marcus Wohlsen

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 173: Going to bat for flu research

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Created on Sunday, 04 March 2012 22:15

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Michael Walsh, and Ashlee Bennett

The TWiVites discuss seroevidence for human infection with avian influenza H5N1, and the discovery of a new influenza virus in Guatemalan bats.

Right-click to download TWiV 173 (85 MB .mp3, 117 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Seroevidence for human H5N1 infection (Science)
• Mammalian-transmissible H5N1 (mBio)
• New information about ferret-adapted H5N1 (NY Times, virology blog)
• New influenza virus from fruit bats (PNAS)
• Elsevier abandons open access assault (The Scientist)
• Le virus le plus dangereux?
• TWiV on Facebook
• Letters read on TWiV 173

Weekly Science Picks

Ashlee - AskScience (Reddit)
Michael - HealthMap (iPhone and Android app)
Rich - H5N1 research discussion at ASMBiodefense
Alan - El Yunque National Forest
Vincent - The Journal of Global Health

Listener Pick of the Week

Judi - NSF visualization challenge

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 172: Two can be as bad as one

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Created on Monday, 27 February 2012 00:10

Written by Vincent Racaniello

Hosts: Vincent Racaniello and Kathy Spindler

Vincent and Kathy discuss how a virus may cause disease distant from its replication site, then review a day in the life of a senior microbiology professor.

Right-click to download TWiV 172 (74 MB .mp3, 102 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Celsius vs Centigrade
• Neuropathogenesis during polymicrobial infection (PLoS Pathogens)
• Tetramer staining (pdf)
• One
• TWiV on Facebook
• Letters read on TWiV 172

Weekly Science Picks

Kathy - Science prize for inquiry-based instruction (Alberts editorial, second winner)
Vincent - The long and winding road to a Ph.D.

Listener Pick of the Week

Greg - Correlation

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 171: One is the loneliest number

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Created on Sunday, 19 February 2012 16:14

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Matt Frieman

Matt joins the TWiVarians to review virus production in single cells and single virion genomics.

Right-click to download TWiV 171 (67 MB .mp3, 92 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• H5N1 results will be published (NY Times)
• Virus production in single cells then and now
• Single virion genomics (PLoS One)
• Multiple displacement amplification (Wikipedia)
• Ranavirus killing turtles, tadpoles in Maryland (Washington Post)
• Three Dog Night
• TWiV on Facebook
• Letters read on TWiV 171

Weekly Science Picks

Matt - H5N1 research discussion
Dickson - The Golden Wand of Medicine by Walter J. Friedlander
Alan - Imagine Science Films
Vincent - E. coli: Good, Bad, and Deadly

Listener Pick of the Week

Daniel - The scale of the Universe
Stefan - A Legacy of Achievement

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 170: From variolous effluvia to VLPs

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Created on Sunday, 12 February 2012 20:02

Written by Vincent Racaniello

Hosts: Alan Dove, Rich Condit, and Dickson Despommier

Alan, Rich, and Dickson discuss Edward Jenner's paper on cowpox vaccine, then move 200 years later to modern vaccines against norovirus, influenza H5N1, and more.

Right-click to download TWiV 170 (72 MB .mp3, 100 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Norton Zinder, 83 (Reuters)
• Jenner's cowpox vaccine paper (Bartleby, Gutenberg)
• Norovirus VLP vaccine (NEJM)
• Plant-grown H5N1 VLP vaccine (Reuters, PLoS One)
• Plant-grown norovirus VLP
• Hexavalent pediatric vaccine
• TWiV on Facebook
• Letters read on TWiV 170

Weekly Science Picks

Dickson - High-speed photography of falling drop
Rich - Biotechnology Research in an Age of Terrorism (NAP)
Alan - Lab Report videos (YouTube)

Listener Pick of the Week

Jim - The Blind Spot

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 169: Epidemiology causes conclusions

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Created on Sunday, 05 February 2012 23:05

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Michael Walsh

Michael and the TWiV team review epidemiology basics, including fatality ratios.

Right-click to download TWiV 169 (64 MB .mp3, 152 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Michael's blog and podcast
• Epidemiology literature critique (PowerPoint)
• Seven mistakes in epidemiology (ETE)
• Snow cholera map
• TWiV on Facebook
• Letters read on TWiV 169

Weekly Science Picks

Michael - Love my epi
Dickson - Bacteria array detects arsenic
Rich - Dunning-Kruger effect
Alan - Environmental Economics
Vincent - Don't censor influenza research

Listener Pick of the Week

Simon - The Great Mortality by John Kelly

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 168: Super CalTech prophylaxis and ferret runny noses

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Created on Sunday, 29 January 2012 22:59

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Welkin Johnson

Welkin joins the TWiV team for a discussion of HIV prophlaxis using vectored antibodies, and the influenza H5N1 virus studies in ferrets that were not redacted.

Right-click to download TWiV 168 (59 MB .mp3, 98 minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• Vectored HIV immunoprophylaxis (Nature)
• Vectored immunoprophylaxis - the Movie (YouTube)
• Adeno-associated virus (Wikipedia)
• In vitro evolution of H5N1 towards human receptor specificity (Virology)
• Endogenous viral genes non-essential in chicken (Nature)
• Rates of HIV transmission per coital act (J Inf Dis)
• TWiV on Facebook
• Letters read on TWiV 168

Weekly Science Picks

Welkin - Virtual PI (Nature)
Dickson - Drain the Ocean
Rich - Nova: To the Moon
Alan - Robert Falcon Scott on Twitter and the Terra Nova expedition
Vincent - Hello, Mr. Chips (I, Cringely)

Listener Pick of the Week Charlotte - And the Band Played On

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

TWiV 167: It starts with a cough

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Created on Sunday, 22 January 2012 17:00

Written by Vincent Racaniello

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Alan Dove

The complete TWiVome deconstructs the movie Contagion.

Right-click to download TWiV 167 (53 MB .mp3, 88  minutes).

Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app.

Links for this episode:

• R0 explained (pdf)
• Hendra and Nipah encephalitis (CDC)
• Contagion (IMdB)
• TWiV on Facebook
• Letters read on TWiV 167

Weekly Science Picks

Dickson - Guinea Pig Doctors by Jon Franklin
Rich - Learn to appreciate technology and Everythings amazing and nobodys happy (YouTube)
Alan - JD Hooker slide collection
Vincent - iTunes U app and iBooks Author

Listener Pick of the Week Judi - Makers of Many Things by Eva March Tappan

Send your virology questions and comments (email or mp3 file) to This email address is being protected from spambots. You need JavaScript enabled to view it. , or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.