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TWiP 18 Letters

Avery writes:

Hello Doctors,

In episode #1 of Twip Dr. Despommier mentioned the gap between protozoans and nematodes with respect parasitism. I wonder if this claim takes into account the fish parasite Buddenbrockia plumatellae. Because its body is vermiform it was long thought to be a worm, but my understanding is that recent DNA analysis revieils it to be of the class cnidarian like jellyfish, hydra and sea anemones. This means, again by my understanding, that it is a parasite which falls between the aforementioned gap.

I am not a scientist and I might be misinterpreting the data. I discovered Buddenbrockia plumatellae while randomly following links on the Tree of Life Web Project. After reading the entry on this little guy I was struck by the idea that the body and behavior of a worm evolved in parallel in two separate organisms; I was also struck by the more general and somewhat eerie feeling that natural forms conceal more diversity and history than we are always able to know. I have read for instance that the complete extinction of one species or another of butterfly may have been obscured by the relative health of a neighboring species of butterfly with identical markings.

Anyway. Thanks you so much for your podcast and for giving interested people like myself an opportunity to learn from experts.


Brent writes:

Hello TWIP!

I love the podcast!! I just read an article in the July/August issue of Mental Floss Magazine. The article talked about the research into a possible Malaria vaccine. The article focused on the research being done by Dr. Stephen Hoffman but it said work is also being do by others. Can you talk about the prospect of a vaccine for a parasite.


Washington, DC

Jim writes:

Faboo podcasts chaps ........twiv and twip.

Just listenening to twip no. 3 though and heard Dick say Aldous was Darwin's bulldog. He was the descendant of T HHuxley of course.
I Guess someone already corrected you , but heck............... glad to be of service.... I dunno much else mind you.

Mucho thanks.


Valentine writes:

Hello Sirs,
I am writing for a couple of reasons.

First is to tell you I really like both the podcasts.

I'm just an ordinary nobody with only what science I picked up in high school and threw reading. I have picked up a lot more thanks to you. You make it very interesting even for those of us not in the "know".
Second and the reason for the subject line. Please please please let people know they can also get your podcast with a podcatcher. I don't use itunes I use Juice podcatcher. I found your podcasts on feedburner and twiv.tv. I believe you would get more listeners if they realized they can find and download your podcast with a podcatcher.

By the by Dixson (hope I spelled that correctly) has a great voice.


Peter writes:


I know this is not part of the "Protozoic Parasites" focus of the show, but it is an amazing example of a parasite altering the behaviour of it's host:




Felix writes:

Dear Doctors,

having listened to your 3 discussions on Malaria I decided to get a
book on the subject.

Heading on over to Amazon, I couldn't see much that caught my eye except:

Mosquito: The Story of Man's Deadliest Foe by Michael D'Antonio, Dr
Andrew Spielman 2002
(for £4)

However, in the latest episode of TWIP you recommended:

The Fever by Sonia Shah (for £13)

which you say you have not yet read.

And then, following your advice, I headed on over to Meet the
Scientist to listen to the episode with Prof. Irwin Sherman, only to
find that he has written a book on Malaria (among others):

The Elusive Malaria Vaccine: Miracle or Mirage by Irwin W. Sherman
(for £28)

He also seems to have a new book out on the 1st Oct:

Magic Bullets to Conquer Malaria by Irwin W. Sherman (for £28)

So my request to Prof Despommier would be, once you have read Sonia
Shah's book (if you intend to), please advise your loyal listeners
which one book on Malaria out of the many available you would

I am looking forward to your forthcoming episode on Malaria with Dr
Knirsch to learn even more.

You often say that such-and-such a friend or acquaintance of yours
would be a great guest - but they don't materialise!
I DON'T CARE you 2 guys together are all I need.

Live long and podcast!


Arsen writes:


You asked us to design an experiment to confirm, if toxoplasmosis indeed increases the probability of mice being eaten in the wild. The constraint was that we shouldn't influence the behavior of the mice in any way.
What about if we measure cats instead?

We could take 2 remote islands. On one there would be no mice or cats infected with toxoplasmosis, on the other toxoplasmosis would be prevalent. Both islands would be habitable for mice, and would not have any natural predators for them (except cats, which we also would introduce). Also, besides mice, both islands wouldn't have any food for cats.

What we would measure would be the amount of fat the cats would have accumulated during the summer. If indeed toxoplasmosis increases the probability of mice being eaten, we should be able to detect statistically significant difference in the mass of fat, accumulated by cats on both islands.


Akhil writes:

Hello Vince and Dick...

You guys are the foundation of my razor sharp knowledge on Parasitism and Viruses in my class. I hated it but I gave away the secret to my knowledge to other students in the class they are all subscribers now.

I am originally from India so I would love to tell you guys how to say Kala Azar (Black Fever). I would love to tell Dr. Despommier as his narration is impeccable and our king deserves every jewel in his crown.

It is said Kah-La like La La not Kay-la like Layla... Kay La means Banana in India.

Azar is said like Uh-Zur.... Uh from Uh-Oh and Zur from Leisure, Teaser, Seizure.

everybody writes quite formal emails... so i should say, you guys are totally RAD.

Hey Prof. Vince I am not smart enough to enter contests now but I will compete for Drobo by the time they have a neural chip.
Dr. Vince if possible please explain us any Virus Origin Hypothesis on Twiv.. sorry if I missed them on any podcast.


Raphael writes:

Good day, Drs. Vincent and Dickson!

Just sharing you a link through email from Symposier about Trypanosomiasis/Chagas' Disease, a good historical background as well as images and videos of actual parasite invasion of cells.



Lars writes:

Hello Twip team,

Did you hear about the study that showed that Plasmodium falciparum
had jumped not too long ago from Gorillas to the human race.

Keep up the good work with the TWIV and TWIP podcasts!
As a Ph.D. student in plant/agricultural sciences I dont have much use
of the podcast content for my work but I really like to
listen to TWIP and TWIV while preparing samples and when i have some
spare time.

Greetings from Germany


Richard writes:

Dear Dickson and Vincent,

While listening to TWIP episode 15 "Tryp the light fantastic" Dickson referred to Rhodesia as being named after the Dutchman Rhodes.

Cecil Rhodes was certainly not Dutch. See if you can guess where he was from based on the following quotation, courtesy of wikipedia;

"Remember that you are an Englishman, and have consequently won first prize in the lottery of life."

Thank you for the wonderful TWIP episodes so far. Our research group recently started a programme looking at the impact of IRS on malaria in an area around Lake Victoria. Its a 21h drive from where I am based and we got through many, many episodes of TWIP and TWIV so far during the drive! Makes the time fly by.

Long live TWIP and TWIV!



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