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TWiM 36 Letters

Todd writes:

Just a quick note to say how much I enjoy TWiM, and in particular, how much I enjoyed episode 32 featuring Rosie Redfield. I don't know how you find time to do this, but I'm glad you do. Keep up the great work.

BTW, I was also fortunate enough to attend the SGM meeting in Dublin in March. I enjoyed hearing you talk about the use of new media, as well as the rest of the meeting. I was also impressed at the weather they arranged for us! I entered Dublin into my phone's weather app several weeks before the meeting, and haven't yet removed it. I haven't seen a single week with weather as nice as ours before the meeting or since.

Spyros writes:


My name is Spyros and I'm a manager of a Biological Quality lab in a pharmaceutical plant.  I'm in the process of listening to all your podcasts and I really like it.  I have a Microbiology degree (Bachelors) from the University of Illinois at Urbana-Champaign, so I don't have the education of a lot of your friends / guests, but what I may be able to bring to the show a different perspective. I remember in one of the first ones, a lab tech from industry called in and asked some general questions.

I don't know if this has been brought up or were looking from someone from industry to speak on topics of pharmaceutical manufacturing and controlling flora in the environment,  monitoring we do, what we monitor, what we monitor for and general career advice.

I probably will have to work with my company's public affairs division and probably legal around what I can / can't say but I will only do that if you would be interested in having me on the show.  I don't know the exact time commitment but I will arrange to meet it if possible.  I live in free online casino bounuses North Carolina, and I know one of you regular contributors is in South Carolina, so, you would have the Carolina's covered!

I'm only on episode 6 so if you have this covered I understand.  Keep on going really enjoy the topics.


Sarah writes:

Hi Vincent and guests,

I have been an avid listener of the TWIM/V/P podcasts for just over a year now; they help pass the time during long animal surgery hours, even longer stereology sessions, as well as during my rollerblade home from work in Los Angeles... yes I know it's dangerous to wear headphones and rollerblade in a city where people care more about the scratches on their car than a pedestrian's broken bones if a collision occurs, but hey we all have to take risks for science right?

My question is a little delayed in terms of timing; it was sparked from the January 26th podcast looking at a possible role for microbes in the onset of autism. It was mentioned in the beginning anatomy lesson that the appendix may have a role in priming the gut microbiome. I know there has been at least one study that has shown a correlation between appendectomy and an increase in heart disease in humans, and I also found a paper linking germ-free mice with an increase in atherosclerotic plaque formation. I'm curious if you or your colleagues have any postulates regarding which particular group/groups of bacteria in the appendix may be the "keystone genus" within the community- knocking them out will potentiate the results found in the germ-free mice in terms of plaque formation or other early markers of heart disease. I guess if you were going to look more closely into causal links between appendix, gut microbiota and heart disease, where would you start and why?

I hope that question made sense and thanks again for the hours of entertainment...enjoy the Spring weather!


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