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MWV Episode 94 - TWiM #99: Careers in Biodefense
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Inspiration for 2015 via the Late, Great Randy Pausch!

The late computer scientist Randy Pausch wrote many inspirational things about life and academia during his struggle with pancreatic cancer. As we approach 2015, his words are helpful to me, and perhaps to others. About life, about academia, about helping others...and making our dreams come tr... Read More

BacterioFiles 197 - Fucose Feeds Friendly Fighters

This episode: When sensing an infection, mice make sure to keep their gut bacteria well-fed. And it pays off!


(11.8 MB, 13 minutes)


Show notes: 
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TWiV 317: Brazil goes viral

On his second trip to Brazil, Vincent joins Eurico to speak with four young virologists, Gustavo, Cintia, Tatiana, and Suellen, about their work and their prospects for careers in science.


Host:  Read More

Should you consider attending ASM 2015 this spring?

The general program for the 2015 American Society of Microbiology meeting in New Orleans is out, and registration is now open. The sessions look incredible, and I've listed them below as I imagine they might resonate with many of the readers of this blog. The bolded sessions look particularly in... Read More

TWiM #94: Nitrochondria

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

Merry Luxmas and Happy Microbial Holidays to All!

Here is my annual blogpost using #MicrobialSupremacy to wish all readers a very, very happy holiday season. I do this GFP and prodiosin, as well as luciferase! Enjoy a tiny bit of microbial art, relevant to the season? Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.


Hosts: Vincent Racaniello Read More

BacterioFiles 195 - CRISPR/Cas Cuts Cancer Causers

This episode: Bacterial antivirus system could treat chronic herpes virus infections!


(10.9 MB, 11.9 minutes)


Show notes: 
Journal Paper


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TWiV 315: Must be something in the water

Vincent, Alan, Rich and Kathy discuss the association of a virus with sea star melting disease, and the finding of a phycodnavirus in the oropharynx of humans with altered cognitive functions.


Hosts: Vincen... Read More

How influenza virus infection might lead to gastrointestinal symptoms

Human influenza viruses replicate almost exclusively in the respiratory tract, yet infected individuals may also have gastrointestinal symptoms such as vomiting and diarrhea. In mice, intestinal injury occurs in the absence of viral replication, and is a consequence of viral depletion of the gut... Read More

A novel plate based method for screening DOPA / melanin producing bacteria

Team of researchers guided by Dr.Sarita G Bhat had developed a novel plate based screening technique for DOPA/melanin producing bacteria.Screening was based upon the clear zone formation on a medium suplemented with L-tyrosine.This new approach can be utilized in faster and accurate screening of... Read More

Supercomputer Modelling of a Complete Human Viral Pathogen: Poliovirus (Polio virus)

Follow the reconstruction and simulation of poliovirus using the BlueGene/Q supercomputer at the Victorian Life Sciences Computation Initiative. The poliovirus model is being used as a basis for understanding antiviral drugs, virus infection and helps us to learn how to model related viruses suc... Read More

Viral genomes in 700 year old caribou scat

Recovering viral genomes from ancient specimens can provide information about viral evolution, but not many old nucleic acids have been identified. A study of 700 year old caribou feces reveals that viruses can be protected for long periods of time ā€“ under the right conditions. Read More

BacterioFiles 194 - Squirrel Sequence Stops Similar Sickness

This episode: Remnants of viral infection left behind in squirrels' genome may protect them from incoming viruses!


(9.3 MB, 10.1 minutes)


Show notes: 
Jou... Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.


Host:  Read More

BacterioFiles 193 - Milk Modifies Monkey Microbes

This episode: Being raised with their mother and breastmilk vs. bottle-fed in a nursery significantly affects macaque microbiomes and their immune system profile!


(7.7 MB, 8.4 minutes)


Show notes: 
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TWiV 313: With viruses like these, who needs enemas?

 


Vincent, Alan, and Rich discuss how norovirus, an enteric virus, can replace the functions of the gut microbiome.


Hosts: Vincent Racaniello Read More

MWV Episode 92 - Ebola: On the Front Lines

The current Ebola virus outbreak in West Africa has sickened over 14,000 people and has killed over 5,100. Health workers from around the world are attempting to halt this deadly disease. On November 19th, the American Society for Microbiology featured two of these health workers, Dr. Joseph ... Read More

BacterioFiles 192 - Susceptibility Separates Streptococcus Strategies

This episode: Pathogenic and non-pathogenic microbes have different strategies for interacting with us, even when they have a common ancestor!


(14.9 MB, 16.3 minutes)


Show notes: 
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TWiV 312: She sells B cells

The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.


Hosts:  Read More

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