The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.
Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More
Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More
This article discusses the famous pump handle that John Snow may or may not have had removed ... read the article to get the true story. From medical historian Peter Vinten-Johansen. Read More
This episode: Scientists engineered E. coli to seek and destroy pathogens!
(10 MB, 11 minutes)
A bacterium can sense pathogens in the body, swim toward them, and release a deadly biofilm-busting payload. This process is called pseudotaxis, and could be modified for many... Read More
Here I remember a person who a great deal of influence on my views about microbiology in the classroom, and the laboratory: the late Abigail Salyers. RIP, Abigail. Read More
In this blog post, I describe some "rules for academics" as well as my own "rules for research." I hope that readers find them useful and perhaps a bit humorous. Read More
This episode: Gut bacteria may convert cortisol into important human hormones!
(6 MB, 6.5 minutes)
Note: Episode 144 is now available too. Sorry about that. Not sure what went wrong there, but it is regrettable.
A minor player in the gut, Clostridium scindens,... Read More
Emergence of antibiotic resistance and extended spectrum β- lactamase (ESBL) among uropathogens in the pediatric unit of hospitals created serious health care concern. This study deals with antimicrobial susceptibility and ESBL analysis of uropathogenic Escherichia coli isolate... Read More
Did you see this paper in PLoS Computational Biology? It's mind-blowing. U. Maryland researchers found evidence for Acinetobacter and Pseudomonas nucleic acid integrated into human chromosomes and mitochondria, po... Read More
This episode: Bacteria could reduce mercury's toxicity in their environment!
(6.5 MB, 7 minutes)
Methanotrophs (bacteria that use methane for their carbon and energy) secrete siderophore-like compounds that are usually used to chelate copper and make it more bioavailable, but ... Read More
The hemagglutinin (HA) and neuraminidase (NA) glycoproteins of the influenza virus particle serve distinct functions during infection. The HA binds sialic acid-containing cellular receptors and mediates fusion of the viral and cell membranes, while the NA removes sialic acids from glycoproteins.... Read More
New recommendation encourages physicians to prescribe _antibacterials_ instead of antibiotics for bacterial infections. This recommendation is based on compelling evidence that the word "antibiotic" confuses almost everyone, including some doctors. The confusion leads to strong patient demands... Read More
Dr. Naowarat Cheeptham, is a famous cave microbiologist. Dr. Cheeptham has been fascinated with the world of biology since she was out catching butterflies as a child with her father in her native country, Thailand. Her interest in microbiology developed while studying at Chiang Mai University ... Read More
For anyone interested in Antibiotic Awareness Week, a big part of the story is that patients (or their parents) demand antibacterials even for viral infections. And doctors often comply, just to get rid of them (the patients, that is). This high-resolution PDF can be printed out for waiting ro... Read More
New Massive Online Open Courses (MOOC) in Spanish about Pandemics and new viral infections.
This is a mini online open course about basic concepts of virus and pandemics. We answer questions as what is a virus?, how a virus multiplies inside a cell?, what is a pandemic?, why appear new influe... Read More