Because viruses must bind to cell surface molecules to initiate replication, the use of soluble receptors to block virus infection has long been an attractive therapeutic option. Soluble receptors have been developed that block infection with rhinoviruses and HIV-1, but these have not been licen... Read More
An otherwise balanced review of selected aspects of Ebolavirus transmission falls apart when the authors hypothesize that ‘Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.’
The idea that Ebolavirus might become transmitted by the respiratory route ... Read More
Call for Stories
Caring for People Infected with Ebola: Stories from the Frontlines
Narrative Inquiry in Bioethics will publish a collection of personal stories from individuals who have been at the frontlines of healthcare for Ebola patients—whether as healthcare workers, family caregivers,... Read More
This episode: Bacteria living in plants could help plants clean up cancer-causing pollutants!
(6.9 MB, 7.5 minutes)
Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).
Thick blood smears is de rigueur.
Vincent, Dickson, and Daniel present a new case study, and discuss the effect of chronic malaria infection on wild warbler life span and telomere degradation.
I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More
The entry of enveloped viruses into cells begins when the membrane that surrounds these virus particles fuse with a cell membrane. The process of virus-cell fusion must be tightly regulated, to make sure it happens in the right cells. The fusion activity of measles viruses isolated from the brai... Read More
This episode: Programming bacteria to sense and keep genomic records of environmental inputs!
(15.9 MB, 17.4 minutes)
In this short blog post, I "write" on Petri dishes with bioluminescent bacteria to create words and poems in "living light." I also write a haiku to quorum sensing in the same style! Read More
Presentation by Anthony S. Fauci, MD, Director, NIAID/NIH, Bethesda, MD, at the ASM Biodefense 2015 Meeting in Washington, D.C. on Feb 11, 2015. Read More
Jason Roberts, a virologist at the Victorian Infectious Disease Reference Laboratory in Melbourne, Australia, creates three-dimensional simulations of viruses showing how the molecules that make up the capsid and genome might move in very short periods of time. I visited Jason in his laboratory ... Read More
This episode: Bacteria from wastewater treatment sludge can produce lots of biodegradable plastic!
(7.1 MB, 7.75 minutes)
The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague — according to a citywide microbiome map published today by Weill Corne... Read More
Vincent, Dickson, and Daniel solve last week's case study, present a new one, and reveal how secreted proteins from a helminth prevent diabetes in mice.
Dear Vincent, Dickson and Daniel,
I like your idea of a TWIP coffee mug prize (or maybe a mug discount).
In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More
Animal associated S. aureus are distinct from human strains but some recent studies suggested the human infection caused by animal origin strain of MRSA. Extensive and unregulated use of antibiotic in animal husbandry might be one of the causes for development of multidrug resistant strain. Tran... Read More