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Multi Omics Measurements of Single Samples #mSystems

In systems biology studies, the integration of multiple omics measurements (i.e., genomics, transcriptomics, proteomics, metabolomics, and lipidomics) has been shown to provide a more complete and informative view of biological pathways. Thus, the prospect of extracting different types of molecu... Read More

TWiV 428: Lyse globally, protect locally

The TWiVsters explain how superspreader bacteriophages release intact DNA from infected cells, and the role of astrocytes in protecting the cerebellum from virus infection.


Hosts: Vincent Racaniel... Read More

Bleeding Fungus

Air Collection Data:
Collection Date and Time- February 8, 2016
Weather Conditions and Temperature- 44% relative humidity and 10℃
Collection Location: In the courtyard behind the Savitt Medical Science Building at the University of Nevada, Reno with the collection device facing northeast
Sa... Read More

ASM Members Deliver a Landslide Endorsement for Governance Change - Part 2

In my previous posting (Part 1), I reflected on the historical change of the new ASM governance. Here I would like to highlight some key issues that I see facing ASM and its new governance structure. This is not a prescriptive list, but rather a list of goals or, if you prefer, a straw man for ... Read More

Smartphone microscope turns microbiology into game time

A new 3-D printed, easily assembled smartphone microscope developed at Stanford University turns microbiology into game time. The device allows kids to play games or make more serious observations with miniature light-seeking microbes called Euglena.

When it’s assembled, it has a platform for... Read More

Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “Candidatus Endobugula sertula” of the BryozoanBugula neritina

I thought this area of bryostatin study might spark your interest. It has the potential to treat cancer and Alzheimer’s disease. Whether looking at the way the compound is formed in nature or the challenge of synthesizing the compound is fascinating.

https://www.google.com/search?q=bryozoan+B... Read More

Exams, Science Art, and Learning!

In this blog post, I describe how I encourage microbiology students to draw cartoons about basic concepts in the course. I find that this approach promotes ownership, better comprehension, and gives me better insight into what the students are "seeing" in my class. Read More

Global Warming Damages Symbiotic Organisms

Ten years ago, Takema Fukatsu, PhD, prime senior researcher and leader, National Institute of Advanced Industrial Science and Technology (AIST) in Japan, was invited to Kyoto University as a symposium speaker of a meeting organized by Kenji Fujisaki, PhD, a researcher in the University's Graduat... Read More

Moleculo Facilitates Assembly and Binning from Soil

Soil microorganisms carry out key processes for life on our planet, including cycling of carbon and other nutrients and supporting growth of plants. However, there is poor molecular-level understanding of their functional roles in ecosystem stability and responses to environmental perturbations.... Read More

You Say Auto-phagy, I Say Au-toph-agy: Let's Call the Whole Thing Awfully Amazing

The Nobel Prize for Medicine this year went to Dr. Yoshinori Ohsumi of the Tokyo Institute for Technology for his work on autophagy, the process of digesting unneeded or damaged cellular components. This process plays a role in many central cellular activities, with applications ranging from gen... Read More

"What will change in Clinical Microbiology Laboratories by 2050?"

If you are lucky enough to be still alive and working in 2050... How might the clinical microbiology laboratory have changed by that time? Nobody can accurately predict the future, but here are my personal thoughts... Read More

Virus Watch: Counting Viruses

In this episode of Virus Watch, I show how to do my favorite assay in all of virology - the plaque assay.

Read More

Seeking understanding of the bacterial sec system

How do bacterial proteins destined for export move from inside to outside the cell? As mBiosphere readers may know, there are a number of secretion systems that bacteria use to move materials from inside the cell to outside the cell. Some of these systems, such as the Sec secretion system, are c... Read More

Advancing Phage Therapy

New research conducted at the University of Miami in Coral Gables, Florida and the National Cancer Institute, in Bethesda, Maryland demonstrate that a subset of bacteriophages, dubbed “superspreaders,” potentially play a major role in transmitting antimicrobial resistance. The research, describe... Read More

TWiV Special: Vincent Munster on MERS-coronavirus and Ebolavirus

At the Rocky Mountain Laboratory in Hamilton, Montana, Vincent speaks with Vincent Munster about the work of his laboratory on MERS-coronavirus and Ebolaviruses.


Hosts: Vincent Racaniello Read More

S. mutants mutation increases fluoride resistance


Microbes are excellent at adapting to stressful situations, which is part of the reason antibiotic resistance is a problem today. Constant exposure to antimicrobials such as triclosan have selected for resistant strains, rendering the compound ineffective. This is why the FDA recently banned t... Read More

History Lesson - The Day the US Senate Tried to Change the Name of Salmonella

In an attempt to preserve and defend the good name of the salmon fished in his state, Senator Warren Magnuson (D-WA), introduced in 1969 a bill in the US Senate pro­po­sing to change the name of Salmonella  to the more in­oc­cu­ous sounding Sanella. In some circles it may seem com­for­ting to th... Read More

You're in Control: Talking with the First mSphereDirect-Published Author

The American Society for Microbiology recently initiated an author-directed route of publication for its journal mSphere, called mSphereDirect. This new publishing route allows authors to choose their reviewers ahead of submission, changing the dynamic between authors and their reviewers. Author... Read More

Influenza Viruses by James McSharry, PhD

In this ASM Virtual Lecture Dr. James McSharry, Professor Emeritus, Albany Medical College, describes the structure of the influenza viruses, types of human influenza viruses and their replication in cells, licensed influenza drugs, current influenza vaccines, and the future of influenza vacci... Read More

MetaPalette: a k-mer Painting Approach for Metagenomic Taxonomic Profiling and Quantification of Novel Strain Variation

Taxonomic profiling is a challenging first step when analyzing a metagenomic sample. This work presents a method that facilitates fine-scale characterization of the presence, abundance, and evolutionary relatedness of organisms present in a given sample but absent from the training database. We ... Read More
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