Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More
Viruses are the most abundant biological entities on the planet with approximately 1030 in the world’s oceans at any time. As such, they play a central role in global nutrient cycling. Despite their ecological importance, little is known about how viruses interact with their hosts due to the dif... Read More
Host: Vincent Racaniello
Guest: Peter L. Salk
Vincent meets up with Peter L. Salk to talk about development of the fir... Read More
The abilities of bacterial organisms to utilize the various strategies to resist antimicrobial compounds are all genetically encoded.
Intrinsic resistance is that type of resistance which is naturally coded and expressed by all (or almost all) strains of that particular bacterial species. An... Read More
This article discusses the famous pump handle that John Snow may or may not have had removed ... read the article to get the true story. From medical historian Peter Vinten-Johansen. Read More
In this blog post, I describe how I use the commonly available pGLO plasmid to teach freshman students basic concepts about transformation, receptor recognition, drug resistance mechanisms, and gene regulation. Oh, and fluorescence via GFP! Read More
This week’s virology question comes from Eric, who writes:
I’m working on an MPH and in one of my classes we are currently studying the influenza virus. I’d forgotten that the genome is in 8 separate parts. Curious, I’ve been searching but can’t find any information as to why that is?
What... Read More