The TWiP trio solve the case of the bug bites all in a row, and talk about a secreted Toxoplasma protein that is central to the parasite's manipulation of host cells.
Vincent speaks with David Tuller about flaws in the U.K's $8 million PACE trial for chronic fatigue syndrome, and efforts to have the trial data released.
Host: Vincent Racaniello
Gue... Read More
Today it is well known that viruses may contain DNA (poxvirus, mimivirus) or RNA (influenza virus, Zika virus), but for many years it was thought that genomes were only made of DNA. The surprise at finding only RNA in a virus is plainly evident in a 1953 letter from Harriett Ephrussi-Taylor to J... Read More
Nels and Vincent launch a new podcast on evolution, This Week in Evolution (TWiEVO) and start by discussing how the field has changed through recent mergers of evolutionary and experimental biology in the post-genome era. Read More
In Zanzare, the new comic from Cimaza (www.cimazacomics.com/), we are plunged head-first into the global mystery of the Zika virus. We meet the mosquitoes (in Italian: zanzare) implicated in its spread; but the insects plead their innocence, saying it's all a misunderstanding. They lay their cas... Read More
Zika virus RNA has been detected in New World monkeys from the Northeast region of Brazil. This finding suggests that primates may serve as a reservoir host for the virus, as occurs in Africa. Read More
This upcoming Monday, Chipotle restaurants across the country will close as its employees discuss food safety and safe food handling. The restaurant was in the news throughout the last half of 2015, beginning with an outbreak of E. coli in Seattle (which was kept secret!), followed by another E.... Read More
Data from several clinical studies in Brazil establish a strong link between infection of pregnant women with Zika virus and a variety of birth defects collectively called congenital Zika syndrome.
In the latest study conducted in Rio de Janeiro, the authors enrolled 88 pregnant women who had... Read More
From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy - using viruses to treat cancers.
Hosts: Read More
Not long after the appearance of an outbreak of viral disease, first scientists, and then newswriters, blame it all on mutation of the virus. It happened during the Ebolavirus outbreak in West Africa, and now it’s happening with Zika virus.
The latest example is by parasitologist Peter Hotez,... Read More
Since the first outbreak of Ebola virus in 1976, the frequency and scale of the deadly disease’s outbreaks have increased. The 2014-2015 outbreak in West Africa caused 11,000 deaths, precipitated panic at airports and emergency rooms worldwide, and renewed the urgency to find cures.
Kartik ... Read More
The TWiV team takes on an experimental plant-based poliovirus vaccine, contradictory findings on the efficacy of Flumist, waning protection conferred by Zostavax, and a new adjuvanted subunit zoster vaccine.
Hosts: Read More
One of the important tasks of Public Health England’s Mycology Reference Laboratory is to identify any newly emerging fungal pathogens that could become a public health risk. In recent months, the lab had tracked several clusters of Candida auris infections in British hospitals. The multidrug-re... Read More
While our human biochemical reactions are limited, our ingenuity is not, and scientists are able to exploit microbes for our benefit, such as in chemical spills. Using microbes to degrade or sequester toxic molecules is one form of bioremediation, and has many various applications. Famously, sci... Read More
This past weekend, I went to visit a friend and meet his twin toddler boys for the first time. Though both boys eagerly ran around the playground we visited, one was just slightly less active. “He has asthma,” his dad explained to me, “but his brother doesn’t.” Why would two boys with the same e... Read More
Despite increasing awareness of Klebsiella pneumoniae as a public health risk, there has been relatively little understood about its mechanisms of pathogenesis.
The bacterium, estimated to be the third most common cause of hospital-acquired infections in the United States in a recent study, c... Read More
Death from influenza virus in older people may be primarily caused by a damaging immune response to flu and not by the virus itself, new research suggests.
Ninety percent of the deaths attributed to flu each year worldwide occur in people aged 65 and older. To understand why older adults are ... Read More
The TWiP troika solve the case of the Female from the Bronx, and reveal how feeding on different plants affects mosquito capacity to transmit malaria.
Bitter tasting yogurt or cheese may not make it to your refrigerator, but it is produced and the result of pesky bacteria. The microbial composition of raw milk impacts the quality, shelf life, and safety of processed milk and other dairy products. Controlling the quality of these products is tr... Read More
This episode: Predatory bacteria have a particular protein that protects them from their own prey-damaging enzymes!
(7.3 MB, 7.9 minutes)