The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More
This episode: Parasitoid wasps spread helpful bacterial symbionts between their whitefly prey!
(10.9 MB, 11.9 minutes)
This is fun, and although I'm sure someone will gripe about Dicksons enthusiastic response to the crayfish, it made my life easier. I think it's Paragonimus kellicoti. As for eating raw crayfish; how drunk... Read More
Host: Vincent Racaniello
Guests: Carla Giles, Zoe Dyson, Brianna McLean, and Caitlin O'Brien
In Melbourne, Australia, Vincent speaks with four PhD students about their research projects and what... Read More
Back in 2013 I built a Wall of Polio in my laboratory – a large stack of six-well cell culture plates that have been used to measure the concentration of polioviruses in various samples by plaque assay. It became a focal point of the lab at which many guests came to have their photographs taken.... Read More
A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More
The Sabin infectious, attenuated poliovirus vaccines are known to cause vaccine-associated paralysis in a small number of recipients. In contrast, the Salk inactivated vaccine does not cause poliomyelitis. Why are the Sabin vaccines still used globally? The answer to this question requires a bri... Read More
Here is a follow-up to last week’s article that described a case of variant Creutzfeldt-Jacob disease in a Texas resident caused by ingestion of BSE-contaminated beef 14 years ago.
A 59 year old male patient was admitted to the trauma unit in Lancaster, PA with a self-inflicted gunshot wound ... Read More
A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?
This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More
The late Edward Leadbetter had a huge impact on my life as an academic, and a microbiologist. In this post, I try to give some appreciation to what he meant to me. Read More
Dear Dr.s R, D & G,
I really hate to criticize learned professors, especially my elders. I suspect I may be being overly - sensitive or perhaps it is a cultural difference. However, the "over-talking" is decreasing the qualit... Read More
As my Fall semester approaches, I am reflecting on last Fall. I taught a freshman seminar course revolving around symbioses and parasitism, and was fortunate to have many well known scientists be willing to "virtually visit" my class! Here is my report from last year on the great Jack Gilbert.... Read More
Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short... Read More
I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More