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Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

MWV94 - TWiM #99: Careers in Biodefense

Hosts: Vincent Racaniello


Guests: Maria Julia Marinissen, Read More

TWiV 301: Marine viruses and insect defense

At the International Congress of Virology in Montreal, Vincent speaks with Carla and Curtis about their work on RNA interference and antiviral defense in fruit flies, and viruses in the sea, the greatest biodiversity on Earth.


Host:  Read More

BacterioFiles 209 - Myxococcus Menace Motivates Megastructures

This episode: Microbial predators in soil cause microbial prey to build fortifications!


(8.8 MB, 9.5 minutes)


Show notes: 
Journal Paper


Read More

MdlM113: Microorganismos Halofilos Extremos y los virus que las infectan con Josefa Anton

Ambientes extremos: salares del mundo, su microbiota y los virus presentes. Estos son los temas a discutirse en el episodio de hoy de La Radio el Mundo de los Microbios. Nuestra invitada la Dra. Josefa (Pepa) Anton, Catedrática Asociada de la Universidad de Alicante compartirá sus estudios so... Read More

MWV96 - Antibiotic Resistant Bacteria

In 2011, the NIH Clinical Center had a cluster of infections of a pathogen that tops the CDC's list of urgent threats: antibiotic-resistant Klebsiella pneumoniae. This bacteria, which can cause bloodstream and other infections, has recently developed resistance to the class of antibiotics kno... Read More

TWiP 91: Born to deform

 Vincent, Dickson, and Daniel review how Viagra might be used to block transmission of Plasmodium falciparum, and introduce a new case study.


Hosts:  Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More

Honoring the Memory of Another

The late Edward Leadbetter had a huge impact on my life as an academic, and a microbiologist. In this post, I try to give some appreciation to what he meant to me. Read More

Freshman Symbiosis Course and Jack Gilbert!

As my Fall semester approaches, I am reflecting on last Fall. I taught a freshman seminar course revolving around symbioses and parasitism, and was fortunate to have many well known scientists be willing to "virtually visit" my class! Here is my report from last year on the great Jack Gilbert.... Read More

BacterioFiles 216 - Probiotic Promotes Peanut Permissiveness

This episode: Kate Franz and Matt Woodruff from Audiommunity join me to talk about a clinical trial of peanut immunotherapy with probiotics to treat peanut allergies!


(29 MB, 31.75 minutes)


Show notes: 
Read More

BacterioFiles 219 - Fungi Facilitate Photosynthetic Fuels

This episode: Fungi can act like sticky nets to help harvest algae for biofuels!


(8.3 MB, 9 minutes)


Show notes: 
News item/ Read More

BacterioFiles 206 - Mollusc Maneuvers Microbe Machines to Macerate Maples

This episode: When digesting wood, shipworms outsource their microbial symbionts from gut to gills!


(9.7 MB, 10.6 minutes)


Show notes: 
Journal Paper<... Read More

TWiV 307: Ebola aetiology

Tara Smith joins the TWiEBOVsters to discuss the Ebola virus outbreak in west Africa, spread of the disease to and within the US, transmission of the virus, and much more.


Hosts: Vincent Racaniello Read More

TWiV 351: The dengue code

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Transgenic pigs resistant to foot-and-mouth disease

Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short... Read More

A Green Thumb for Ocean Microbes

MIT-WHOI Graduate student Kristen Hunter-Cevera describes the challenges and obstacles involved with growing marine microbes (in her case, Synechococcus) in a laboratory setting, and outlines the value of her research in understanding marine biogeochemistry. Read More

BacterioFiles 212 - Ghosts Get Good Guarding

This episode: Bacterial ghosts could make good vaccines for different things!


(9.8 MB, 10.7 minutes)


Show notes: 
Journal Paper


Read More

TWiP 81 letters


Allan writes:


Dear Vincent & Dickson… and Daniel,


I always enjoy listening to TWIP here in Kona, Hawaii.


Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
(FREEZING, as few of us hav... Read More

Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?

This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More
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