Nearly four months ago I stood at the front of a crowded classroom at Columbia University and began teaching the third year of my undergraduate virology course. Twice a week we discussed the basic principles of virology, including how virions are built, how they replicate, and how they cause dis... Read More
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Why is there such widespread fear of avian H5N1 influenza virus?
Why did Paul Keim, chair of the National Science Advisory Board for Biosecurity (NSABB) say “I can’t think of another pathogenic organism that is as scary as this one”. What lead Donald McNeil, writing about H5N1 in the New Yor... Read More
I would just like to start by saying thank you for the wonderful podcast.
Today I found this article (http://www.npr.org/templates/story/story.php?storyId=127226355) on npr which seems to describe a remarkably effectiv... Read More
Vincent and Dickson review the life cycle and pathogenesis of the world's most unusual parasite, Strongyloides stercoralis.
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I hear from many readers that they routinely get the flu vaccine every year, yet they often contract the disease. I usually tell them that the vaccine is not perfect: it doesn’t protect everyone who gets it. Now we have the numbers to back up this statement, and they are not pretty.
Having upped my daily dose of podcasts I stumbled upon This Week In Science. The latest show (http://www.twis.org/audio/2010/03/09/438/) they mentioned something that probably comes within your sphere of interest, namely the fin... Read More
RSS stands for really simple syndication. It's an acronym encompassing various data formats (xml, atom, rss, rdf) used for providing users with frequently updated content. RSS also allows... Read More
Gentlemen, I think you'll find that Dylan Thomas was Welsh, not Irish. Though you are of course correct on his penchant for writing and
Dear TWiV Doctors,
I have one question and one co... Read More
Fungi can be found in rising bread, moldy bread, and old food in the refrigerator, and on forest floors. Most decompose non-living things, but some damage crops and plants. A few cause problems in people, such as Candida, which causes yeast infections.... Read More
The retrovirus XMRV arose during passage of a human prostate tumor in nude mice. The genomes of these mice contain two different proviral DNAs related to XMRV, pre-XMRV-1 and pre-XMRV-2, that recombined to produce XMRV that has been isolated from humans. Two other prostate cancer cell lines also... Read More
The fatality rate for human infections with avian influenza H5N1 is widely quoted at >50%, based on the number of deaths among the fewer than 600 cases confirmed by the World Health Organization. Wang, Parides, and Palese suggest that this number is an overestimate. Read More
Welkin Johnson, Assistant Professor of Microbiology and Molecular Genetics at Harvard Medical School and an Associate Blogger for Small Things Considered, ponders the "fossil record" of viruses:
"As a scientist fascinated with the evolutionary interplay between viruses and their hosts, I admi... Read More