A dairy cow in California is the fourth known American case of mad cow disease, which is caused by prions, infectious agents composed only of protein (the story hit the press the day after my lecture on this type of illness). Unlike viruses, prions have no nucleic acid and no protective coat. Bu... Read More
A salt-loving (halophilic) bacterium which can grow in medium containing arsenic instead of phosphorus has been selected from the microbial community of Mono Lake in California. Arsenic (As) is a chemical analog of phosphorus and is usually toxic because it can enter metabolic pathways in the pl... Read More
Rich Condit found an article highly critical of the original Wakefield study (claiming a link between MMR vaccine and autism) which was published in the same issue of Lancet. He asked the publisher, Elsevier, to open up the article to non-subscribers so he could recommend it as a pick of the wee... Read More
Hello TWiV hosts,
I'm currently working as a technician in the biochemistry and molecular biophysics department at Columbia, having just received my BA from here in the Spring. First of all, I'd like to join the chorus of praises ... Read More
Thanks again for all the effort and care you invest into your podcasts. I'm writing today to suggest a pick of the week: The Nature of Things with David Suzuki. Suzuki, one of Canada's scientist/rock-stars, hosts... Read More
The third annual installment of my virology course at Columbia University, Biology W3310, has begun, and all the lectures will be available online. Read More
A second virophage has been identified. The name does not signify a virus that infects another virus – it means virus eater.
Hello Professor Vincent,
First of all, thank you for your wonderful podcasts! I'm a CFS sufferer and also a student Applied Science so I'm interested in many of the topics discussed for those two reasons and always learning new things.
I... Read More
Hello to the TWiV crew,
Here are a couple of picks I thought would be good for provoking thought and generating discussion...
While working on a project, I came across some papers attempting to define what "critical thinking" means. I app... Read More
A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as s... Read More
Jamie Henzy, a postdoctoral researcher at Boston College, has authored a post on Small Things Considered that explores the shady world of the deltaretrovirus genus.
"Among retroviruses, the deltaretrovirus genus is something of a shady bunch, its members lurking in the shadows, causing troubl... Read More
The virologists who carried out the contentious experiments on influenza H5N1 transmission in ferrets have agreed to remove certain details from their manuscript, according to ScienceInsider. This is a bad day for virology, and for science in general. The decision by the NSABB sets a precedent f... Read More
There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the p... Read More
Australian virologist Frank Fenner, MD was born in Ballarat, Victoria in 1914. He earned a Doctor of Medicine in 1942 at the University of Adelaide, and from 1940 – 1946 he worked on the malaria parasite in Egypt and Papua New Guinea as an officer in the Australian Army Medical Corps. He subsequ... Read More
Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More
To the TWiVerati Intelligencia,
Each week you begin your show with the tagline, "This Week in Virology: The podcast about viruses, the kind that make you sick."
I recognize that viruses have been responsible for some of the biggest epidemic... Read More
The finding of viral nucleic acid sequences in illegally imported wildlife products has attracted the attention of the New York Times, which published an article entitled From the jungle to J.F.K., viruses cross borders in monkey meat. Read More
Human Lyme disease is caused by a number of related Borrelia burgdorferi sensu lato species. We report here the complete genome sequence of Borrelia sp. isolate SV1 from Finland. Read More
According to the New York Times (Why Science Majors Change Their Minds), the decline in the number of science majors in the United States has come about in part because the subject matter is too difficult. If this explanation is true, then we have not properly prepared these students in grades K... Read More
On the Small Things Considered blog, Michael Schmidt, Professor and Vice Chairman of Microbiology and Immunology at the Medical University of South Carolina, reviews a recent paper entitled "Precise Manipulation of Chromosomes in Vivo Enables Genome-Wide Codon Replacement" by Church and colleagu... Read More