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Ebola Outbreak 2014 2015 by Dr. Fauci

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Finding the key to strengthening the immune response to chronic infections

A team of researchers from The Wistar Institute has identified a protein that could serve as a target for reprogramming immune system cells exhausted by exposure to chronic viral infection into more effective "soldiers" against certain viruses like HIV, hepatitis C, and hepatitis B, as well as s... Read More

TWiV 87 Letters

James writes:


Dear TWIV,


I've really enjoyed hearing about the paths you and your guests took to enter the fields of virology and parasitology.


I was wondering if Dr. Dove could talk for a few minutes about how and why he decided to transition into sci... Read More

Viral bioinformatics: Introduction + Homology

First, you may be asking yourself – Why viral bioinformatics? Good question! Although it’s true that much in the world of bioinformatics can be applied to all manner of protein and DNA sequences, there are a number of resources that are specific for viruses and there are a number of analyses tha... Read More

TWiV 122 Letters

Luke writes:


Hello TWiV hosts,


I'm currently working as a technician in the biochemistry and molecular biophysics department at Columbia, having just received my BA from here in the Spring. First of all, I'd like to join the chorus of praises ... Read More

TWiV 159 Letters

Jenny writes:


Hi Vince and the rest of the TWIV-cast!


You might have come across this news already, but it would be interesting to hear the TWIV gang's take on this study done by Fouchier's group from the Netherlands.


Read More

TWiV 120 Letters

Ashley writes:


Vincent, I am a huge fan of TWIV and thank you and the others for taking time out of your busy schedule to do the program. I have my B.S. in Biology and Chemistry and would love to go back to school. I read textbooks, listen to podcasts from itunesU and... Read More

Alzheimer''s disease plaques and tangles: Repositories of a herpes simplex/immune system battle leading to neuronal destruction

The protein components of the plaques and tangles seen in the Alzheimer's disease brain offer a clue to the origins of the disease: It turns out that they are heavily enriched in human proteins used by herpes simplex during its life cycle: Many immune system related proteins are also found in th... Read More

TWiV 162 Letters

Sarah writes:


Hello to the TWiV crew,


Here are a couple of picks I thought would be good for provoking thought and generating discussion...


While working on a project, I came across some papers attempting to define what "critical thinking" means. I app... Read More

TWiV 90 Letters

Eric writes:


Hi Vincent,


After 86 episodes of TWiV, I am still loving every minute of the podcast and I am constantly impressed with how much I learn. For example, I have been mentoring an undergraduate student in the lab and we have had a rough two week stret... Read More

PLoS Journals Projected to be 100% Self-Sufficient by 2010

The Public Library of Science's open access journals just release its 2009 June Progress Report in which they project "a publishing business model projected to be 100% self-sufficient in 2010."

"PLoS journals use a business model that recovers expenses — including administration of peer revie... Read More

Norton Zinder, 1928-2012

Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More

Building the perfect bug

This past February I was interviewed by the Australian Broadcasting Company on the topic of the Fouchier and Kawaoka experiments on avian influenza virus H5N1. The video, Building the Perfect Bug, has been released by Journeyman Pictures and includes interviews with S.T. Lai, Laurie Garrett, Mic... Read More

TWiV 163 Letters

Ronnie writes:


Hello Professor Vincent,


First of all, thank you for your wonderful podcasts! I'm a CFS sufferer and also a student Applied Science so I'm interested in many of the topics discussed for those two reasons and always learning new things.


I... Read More

TWiV 115 Letters

Vinayaka writes:


Some additional info that I gathered on viruses on the verge of elimination (may or may not be new to you):


It appears that the next virus on the list of FAO to eradicate is PPR virus ( Read More

El Podcast del Microbio Nº 174 y 175. La Historia de Alice Catherine Evans. /The Story of Alice Catherine Evans)



























El podcast del Microbio Nº174 and 175 are dedicated to Alice Catherine Evans, one of the first women microbiologists. Los ... Read More

10 Genes, Furiously Evolving

This is a great article by Carl Zimmer in the NY Times (@carlzimmer on Twitter) about the evolution process of viruses.

"Some viruses use DNA, like we do, to encode their genes. Others, like the influenza virus, use single-strand RNA. But viruses all have one thing in common, said Roland Wolk... Read More

The Lazarus virus

There is an excellent question in the comments to “Are all virus particles infectious?“: if the particle-to-PFU ratio for a virus stock is 10,000:1, and I infect 1,000,000 cells with 10,000 particles, how many plaques would I expect to observe? Answering this question provides insight into the p... Read More

The Rise of Genomic Superspreaders

One hundred million years ago the earth’s climate was much warmer than today and vast inland seas stretched across entire continents. The land was dominated by charismatic megafauna that would one day serve as inspiration for Sir Arthur Conan Doyle’s novel The Lost World. This period is commonly... Read More

TWiV 101 Letters

Russ writes:


I think this image from www.3d4medical.com is great!


This is a cool app for the iPad. This would make a great pick of the week


Russ


Julian writes:<... Read More

Virology at the Deutsches Museum

I just returned from a 17-day, 3,000 km road trip with my family in Europe. When I travel I’m always on the lookout for virus-related information and I found some at the Deutsches Museum in Munich, Germany. This museum showcases science and technology – it has over 100,000 objects illustrating t... Read More
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