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NEJM: The Burden of Disease and the Changing Task of Medicine

At first glance, the inaugural 1812 issue of the New England Journal of Medicine and Surgery, and the Collateral Branches of Science seems reassuringly familiar: a review of angina pectoris, articles on infant diarrhea and burns. The apparent similarity to today's Journal, however, obscures a fu... Read More

XMRV is a recombinant virus from mice

The novel human retrovirus XMRV has been associated with prostate cancer and chronic fatigue syndrome. The nucleotide sequence of XMRV isolated from humans indicates that the virus is nearly identical with XMRV produced from a human prostate tumor cell line called 22Rv1. This cell line was deriv... Read More

TWiV 173 Letters

Judi writes:

A listener pick - since I know you all really enjoy the visualization of science!

http:... Read More

The Rise of Community-Associated MRSA

This teleconference is sponsored by the American Society for Microbiology and will review the history and importance of methicillin-resistant Staphylococcus aureus (MRSA) with a primary focus on the emergence of community-associated MRSA (CA-MRSA). The phenotypic and molecular identification of ... Read More

Conserved amino acid markers from past influenza pandemic strains

A recent paper published on Biomedcenteral by Jonathan E Allen , Shea N Gardner , Elizabeth A Vitalis, and Tom R Slezak discovers that new genetic markers for human host-specificity and high lethality in influenza viruses were identified by considering combinations of amino acids conserved amon... Read More

TWiV 156: Armed and targeted killer meta-analysis

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent RacanielloR... Read More

Aaron J. Shatkin, 77

Aaron J. Shatkin was well known for his work on reoviruses beginning in the 1960s in his laboratory at the Roche Institute of Molecular Biology in Nutley, NJ and then at Rutgers University. He was among the first to appreciate that virus particles contained many different enzymes, such as RNA po... Read More

TWiV 122 Letters

Luke writes:

Hello TWiV hosts,

I'm currently working as a technician in the biochemistry and molecular biophysics department at Columbia, having just received my BA from here in the Spring. First of all, I'd like to join the chorus of praises ... Read More

A bad day for science

The virologists who carried out the contentious experiments on influenza H5N1 transmission in ferrets have agreed to remove certain details from their manuscript, according to ScienceInsider. This is a bad day for virology, and for science in general. The decision by the NSABB sets a precedent f... Read More

TWiV 110 Letters

Jay writes:

Looks like the polio outbreak in the Congo is pretty bad.


http://www.unicef.org/me... Read More

Building the perfect bug

This past February I was interviewed by the Australian Broadcasting Company on the topic of the Fouchier and Kawaoka experiments on avian influenza virus H5N1. The video, Building the Perfect Bug, has been released by Journeyman Pictures and includes interviews with S.T. Lai, Laurie Garrett, Mic... Read More

The Attendee's Guide to Scientific Meetings

Julian Davies, Professor emeritus at the University of British Columbia and a Fellow of the Royal Society, has authored a humorous post on the Small Things Considered blog on the various methods an attendee of a scientific meeting can employ to enhance "maximum satisfaction and poise" one gets o... Read More

Virology at the Deutsches Museum

I just returned from a 17-day, 3,000 km road trip with my family in Europe. When I travel I’m always on the lookout for virus-related information and I found some at the Deutsches Museum in Munich, Germany. This museum showcases science and technology – it has over 100,000 objects illustrating t... Read More

TWiV 152 Letters

Atila writes:

Dear TWiVers,

I have heard recently that some types of herpes virus may protect us from bacterial infections. This made me remember of myxomavirus, viral oncotherapy and how tumor cells have a compromised immune response. Do you think it is possi... Read More

Podcast del Microbio Nº190 y 191. El Cuarto Dominio (The Fourth Domain)

El podcast del Microbio Nº190 and 191 describes the recent metagenomic results that point towards the existence of a 4th do... Read More

Trust science, not scientists

Whether or not the retrovirus XMRV is a human pathogen has been debated since the virus was first described in 2006. The answer is now clear: the results of Blood XMRV Scientific Research Group, along with a partial retraction of the 2009 Science paper describing identification of the retrovirus... Read More

World Tuberculosis Day 2009

Today is World Tuberculosis Day.

"World TB Day, 24 March 2009, is about celebrating the lives and stories of people affected by TB: women, men and children who have taken TB treatment; nurses; doctors; researchers; community workers--anyone who has contributed towards the global fight agains... Read More

Genes, malevolent and beneficial pathogens and autoantibodies in HIV-1/AIDS

Certain viral infections are known to increase or decrease HIV-1 replication or viral load, perhaps by competing with the same receptors, or via immune and other effects.Many autoantibodies in HIV-1 infection also target the immune network and this may well contribute to pathology. Read More

El podcast del Microbio Nº 233. Bacterias come-sushi (sushi-eater bacteria)

El podcast del microbio Nº 233 summarize the findings by Handeman et al (Nature, 464: 908-912.) on the transfer of carbohydrate-... Read More

Genome of arsenic bacterium sequenced

The genome nucleotide sequence has been determined of the bacterium GFAJ-1, which has been suggested to survive in high levels of arsenic and in fact incorporate arsenic into macromolecules. The sequence does not address the controversy over whether the bacterium can utilize arsenic. I suppose t... Read More
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