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A spike for piercing the cell membrane

Some viruses that infect bacteria (bacteriophages) deliver their DNA into the host cell with an amazing injection machine. The tailed bacteriophages (such as T4, illustrated) store their DNA in a capsid attached to a long tail tube that is surrounded by a sheath. At the bottom of the tube is a b... Read More

TWiV 165: The email zone

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Hosts: Vincent Racaniello, Dickson Despommier Read More

TWiV 167: It starts with a cough

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Hosts: Vincent Racaniello, Dickson Despommier Read More

TWiV 188 Letters

Judi writes:


To our TWIV leaders!


If you have a mac with Apps, please go to the app store and download cell images.... I think you'll have a great time going through them.


One other thing - I listened to your show on science reform with interest but I ... Read More

Baruch S. Blumberg, MD, 1925-2011

Glenn Rall, a virologist at Fox Chase Cancer Center, sent me the following note:

Baruch S. Blumberg, Nobel Laureate in 1976 for discovery of Hepatitis B (and the eventual development of the vaccine, which probably has saved hundreds of thousands of lives since its introduction), died this pas... Read More

XMRV is a recombinant virus from mice

The novel human retrovirus XMRV has been associated with prostate cancer and chronic fatigue syndrome. The nucleotide sequence of XMRV isolated from humans indicates that the virus is nearly identical with XMRV produced from a human prostate tumor cell line called 22Rv1. This cell line was deriv... Read More

XMRV, prostate cancer, and chronic fatigue syndrome

Robert H. Silverman, one of the authors on the study implicating the new human retrovirus XMRV as an etiologic agent of chronic fatigue syndrome, has written an excellent review article on the current status of research on the virus. The article is behind a paywall at Nature Reviews Urology, so ... Read More

BacterioFiles Micro Edition 58 - Baculovirus Blocks Bug Behavior

This episode: Viruses take over caterpillars' behavior!


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Download ... Read More

The Rise of Community-Associated MRSA

This teleconference is sponsored by the American Society for Microbiology and will review the history and importance of methicillin-resistant Staphylococcus aureus (MRSA) with a primary focus on the emergence of community-associated MRSA (CA-MRSA). The phenotypic and molecular identification of ... Read More

NEJM: The Burden of Disease and the Changing Task of Medicine

At first glance, the inaugural 1812 issue of the New England Journal of Medicine and Surgery, and the Collateral Branches of Science seems reassuringly familiar: a review of angina pectoris, articles on infant diarrhea and burns. The apparent similarity to today's Journal, however, obscures a fu... Read More

TWiP 33 Letters

Howie writes:



Twivers,


Great podcast!!!


A while ago, Dick made a comment along the lines that Sir... Read More

TWiM 11 Letters

Steve writes:


As a microbiologist I enjoy listening to your broadcasts.  However, I was very disappointed on the one about Salomonella in cantaloupe and E. coli O157:H7 in Lebanon bologna.  Many incorrect statements were made, such as "Salmonella enteritidis is th... Read More

A viral mashup in snakes

If you know anything about snakes you might be familiar with snake inclusion body disease, or IBD. This transmissible and fatal disease affects snakes of a variety of species but has been best studied in boas. The name comes from the presence of large masses (inclusions) in the cytoplasm of cell... Read More

Preparing for the Flu: A Childcare Communications Toolkit

The CDC has just published "Preparing for the Flu: A Communication Toolkit for Child Care and Early Childhood Programs." A .pdf document that provides information and communication resources to help center-based and home-based child care programs, Head Start programs, and other early childhood p... Read More

The Human Lake

Science writer Carl Zimmer writes a masterful blog piece tracing the history of the study of ecosystems, from lakes to the human microbiome. Just one interesting fact: In their lifetimes, individual humans will produce about five elephants worth of microbes. Read More

TWiV 100 Letters

Damon writes:


I've been having an enjoyable time on my commute lately catching up with TWiV. Today I listened to #26 (Poxviruses), which included a discussion of Tysabri and PML. I work at Millipore which sells many products that go into a MAb production train, includ... Read More

India polio-free for one year

A year has passed since the last reported case of poliomyelitis in India, which occurred on 13 January 2011 in a two year old girl in Howrah, West Bengal. Read More

TWiV 120: Ed Niles, a Km Vmax kind of guy

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Hosts: Vincent RacanielloRich Condit, and... Read More

TWiV 179 Letters

Ebrahim writes:


Dear Dr. Racaniello


I was watching the conference in Dublin and I wanted to thank you for sharing my e-mail with the people in the panel, since I saw how nice it was for me to reach the specialists with that ease through TWIV.<... Read More

Virophage, the virus eater

A second virophage has been identified. The name does not signify a virus that infects another virus – it means virus eater.
Read More

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