After the eradication of smallpox in 1980, the World Health Organization called for destruction of known remaining stocks of the virus. The United States and Russia, which hold the known stocks of smallpox virus, have not destroyed their stocks. During TWiV #124, I was surprised to learn that th... Read More
This video shows the process of injecting a a construct with gene manipulated DNA into a C. elegans worm. The outcome in this case was the rolling worm with the green fluorescent protein in it that localized to the body wall muscle, giving the worm the four green stripes along his body. Read More
Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More
The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.
Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More
There is no evidence for further spread among humans of a novel coronavirus recently isolated from two individuals with severe respiratory illness. This conclusion has been drawn after scrutinizing the travels (figure) and contacts of a Qatari adult who was transferred to intensive care in Londo... Read More
The TWiP-scholars solve the case of the Housewife from Kolkata, discuss mutations in the IL17 gene associated with cerebral malaria, and hear a case presentation from guest Michael Libman.
Hosts: Read More
Dear Dr.s R, D & G,
I really hate to criticize learned professors, especially my elders. I suspect I may be being overly - sensitive or perhaps it is a cultural difference. However, the "over-talking" is decreasing the qualit... Read More
Spencer Diamond and Britt Flaherty, PhD students at UCSD, Spencer in the Susan Golden Laboratory and Britt in the James Golden Laboratory, author a post on Small Things Considered about the green potential for cyanobacteria.
"With such famous bacteria as Escherichia coli and Bacillus subtili... Read More
Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Read More
Fragments of an abundant protein produced by the prostate form amyloid fibrils that enhance infection of cells by human immunodeficiency virus type 1. These fibrils, called semen-derived enhancer of virus infection (SEVI), have been found to boost infection of prostate cells by the retrovirus XM... Read More
Documents designed by the CDC to provide information for planning and conducting school-located 2009 H1N1 influenza vaccination clinics that target school-aged children enrolled in school and potentially other groups in the community. The targeted audience for these materials is primarily state ... Read More
I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More
With the advent of the rapid spread of H1N1 it is often a challenge to explain the need to be vigilant about hand hygiene. CNN's Randi Kaye reporting on Anderson Cooper 360 reports on how germs from one sneeze can spread to hundreds, maybe thousands. The video has a great animation and illustr... Read More
I found TWIP just a week ago and feel I've found a home. I'm a pharmacist, usually on the night shift, and stay excited all night listening to you. Parasites have always been my hobby. In fact, I recently divorced one. His life cycle is unique. I get oddl... Read More