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C. elegans micro-injection

This video shows the process of injecting a a construct with gene manipulated DNA into a C. elegans worm. The outcome in this case was the rolling worm with the green fluorescent protein in it that localized to the body wall muscle, giving the worm the four green stripes along his body. Read More

Learning Metagenomic Analysis at EDAMAME2015

I spent a week and a half learning metagenomic analysis in Michigan from some awfully smart and pleasant people. Learn more at the link! Read More

A collection of polioviruses

In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More

TWiM #122: Mayonii, microRNAs and the microbiome

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome. Read More

XMRV infection is enhanced by prostatic protein fragments

Fragments of an abundant protein produced by the prostate form amyloid fibrils that enhance infection of cells by human immunodeficiency virus type 1. These fibrils, called semen-derived enhancer of virus infection (SEVI), have been found to boost infection of prostate cells by the retrovirus XM... Read More

Safely Processing Sprouts - Educational Video

The California Department of Public Health, Food and Drug Branch and the U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition jointly developed this video in cooperation with the Centers for Disease Control & Prevention, university researchers, and industry representati... Read More

TWiV 231: Hepaciviruses and pegiviruses in bats and rodents

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Hosts: Vincent Racaniello, Amit Kapoor, Read More

TWiM #121: A plague of pathogens

Filmed live at ASM Biodefense 2016 with special guests: Rebekah Kading and Wyndham Lathem.


Fr... Read More

TWiV 216: Processing VIRALGUUAACACCAGRNA

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Hosts: Vincent Racaniello, Alan Dove, Read More

Put Your Hands Together

Scientists estimate that people are not washing their hands often or well enough and may transmit up to 80% of all infections by their hands. From doorknobs to animals to food, harmful germs can live on almost everything. Handwashing may be your single most important act to help stop the spre... Read More

Viruses of protozoan parasites may exacerbate human disease

Many protozoan parasites (Trichomonas, Leishmania, Giardia, Plasmodium, Entamoeba, Nagleria, Eimeria, Cryptosporidium) are infected with viruses. These viruses do not infect vertebrates, but their double-stranded RNA genomes are sensed by the innate immune system, leading to inflammatory complic... Read More

TWiM 60 Letters

Kelly writes:


I’m reeling from this episode!! The symbiosis, the web of life, the energies, chemicals, organisms of
evolutionary progression shaping our world naturally and by human intervention with unknown consequences, then you all tie it to the brain microbio... Read More

TWiV 301: Marine viruses and insect defense

At the International Congress of Virology in Montreal, Vincent speaks with Carla and Curtis about their work on RNA interference and antiviral defense in fruit flies, and viruses in the sea, the greatest biodiversity on Earth.


Host:  Read More

TWiV 247: Today's weather in virology

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Hosts: Vincent Racaniello, Alan Dove, Read More

Touch Surfaces and how microbes spread

With the advent of the rapid spread of H1N1 it is often a challenge to explain the need to be vigilant about hand hygiene. CNN's Randi Kaye reporting on Anderson Cooper 360 reports on how germs from one sneeze can spread to hundreds, maybe thousands. The video has a great animation and illustr... Read More

Water you waiting for? Find out more about choosing water filter membranes for DNA and RNA Isolation

We speak with many scientists each week who are working with filtered water for the isolation of microbial DNA and RNA. Because there are many choices for filter membranes, each with their own benefits, choosing the best one for your sample type and microbial load can be confusing. This article ... Read More

TWiV 219: Fauci pharmacy

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Hosts: Vincent Racaniello, Rich Condit, and Read More

How lethal is rabies virus?

When I am asked to name the most lethal human virus, I never hesitate to name rabies virus. Infection with this virus is almost invariably fatal; just three unvaccinated individuals have been known to survive. New evidence from humans in the Peruvian Amazon suggests that the virus might be less ... Read More

Biology By the Numbers

Elio Schaechter from the Small Things Considered blog has brought to our attention a new internet resource called Bionumbers. "It enables you to find in a minute (or less) any common biological... Read More

School-Located Vaccination Planning Materials and Templates

Documents designed by the CDC to provide information for planning and conducting school-located 2009 H1N1 influenza vaccination clinics that target school-aged children enrolled in school and potentially other groups in the community. The targeted audience for these materials is primarily state ... Read More
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