This episode: Virus + bacterial enzyme = cancer killer!
The chromosomal DNA of several mammals has been found to contain sequences related to the nucleoprotein (N) gene of bornaviruses, enveloped viruses with a negative-strand RNA genome. I am amazed by this finding. How did bornaviral DNA get in our chromosomes, and what is it doing there? Read More
This episode: Fruit flies have microbes that help them get more nutrition out of low-quality food!
(8.4 MB, 9.1 minutes)
This episode: Bacteria around rice roots help protect plants from arsenic toxicity!
(10.1 MB, 11 minutes)
In an ideal world, every PI would be a nurturing and challenging mentor who carefully guides your project and is invested in developing your skills as a scientist. In the real world, however, that kind of leadership can be hard to find.
In any case, one of the most important and useful mental... Read More
Is bacterial DNA contamination in your whole genome amplification kit a problem? For microbiologists it sure is. WGA is a technique where the complete genomic content of a sample is amplified non-specifically and at a single temperature (isothermically). The presence of any contaminating DNA in ... Read More
In this audio in spanish language from "El podcast del microbio" I made a resume of the post "Mother's Love" published in Moselio Schaecht... Read More
Great HAI work! I'm not through it yet. I want to question, though, whether fomites are really important in influenza transmission. I don't think so.
[flu can transmit by fomites in guinea pigs: Read More
The TWiP trifecta solves the case of the Woman from Bolivia with Belly Pain, and discuss a method for population modification of malaria mosquitoes using a Cas9-mediated driver gene.
Hosts: Read More
Hi Drs. Despommier and Racaniello,
This week you wondered why the immune-activating receptor for Toxoplasma gondii, TLR11, is present in mice but not in humans. You noted that it looks like there's no selective pressure keeping it around in us an... Read More
Some people think it would be great if scientists could wipe out all the microbial bugs! Should we do it, and why or why not?
We get a lot of requests to track down the nasty bugs that are making people sick. It's true that some microbes cause health problems such as strep throat, chi... Read More
It goes by many names: Delhi belly. Montezuma's revenge. The Aztec two-step. But doctors use one not-so-glamorous term: traveler's diarrhea. Read More
I really enjoyed your podcast about reverse transcription. I was wondering what makes retroviruses like HIV impossible for our bodies fight off. Are there any retroviruses that can be eliminated from the body?
I was browsing on the "Chronic ... Read More
Host: Vincent Racaniello
Guests: Read More
Dear Vincent & Dickson… and Daniel,
I always enjoy listening to TWIP here in Kona, Hawaii.
Our weather today is 79ºF and clear but we have just experienced a record 25-year overnight low of 54ºF,
Hiroshi Nakaido, PBD Faculty Scientist, Structural Biology Department, and Professor of Biochemistry and Molecular Biology, UC Berkeley, has authored a guest post on the Small Things Considered Blog regarding the limitations of LB medium.
"LB broth contains, per ml, 10 mg tryptone (... Read More