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Everyday Roles

Some people think it would be great if scientists could wipe out all the microbial bugs! Should we do it, and why or why not?

We get a lot of requests to track down the nasty bugs that are making people sick. It's true that some microbes cause health problems such as strep throat, chi... Read More

Gut microbes influence defense against influenza

The bacteria in our intestines outnumber by tenfold the 100 trillion cells that comprise the human body. This gut microbiota has many beneficial functions, including the production of vitamins and hormones, fermentation, regulation of gut development, and shaping intestinal immune responses. The... Read More

TWiV 308: The Running Mad Professor

Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.

Host: Vincent Racaniello Read More

BacterioFiles Micro Edition 147 - Clostridium Conquers Colleagues

This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!

(7 MB, 7.5 minutes)

When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More

BacterioFiles Micro Edition 69 - Plants' Prokaryotic Partners

This episode: Plants open up their roots to let bacteria in!

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Read More

A collection of polioviruses

In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More

Viruses of protozoan parasites may exacerbate human disease

Many protozoan parasites (Trichomonas, Leishmania, Giardia, Plasmodium, Entamoeba, Nagleria, Eimeria, Cryptosporidium) are infected with viruses. These viruses do not infect vertebrates, but their double-stranded RNA genomes are sensed by the innate immune system, leading to inflammatory complic... Read More

How lethal is rabies virus?

When I am asked to name the most lethal human virus, I never hesitate to name rabies virus. Infection with this virus is almost invariably fatal; just three unvaccinated individuals have been known to survive. New evidence from humans in the Peruvian Amazon suggests that the virus might be less ... Read More

Anatomy of a Pandemic

CBCNews.ca has a really great interactive time line that "illustrates some key dates in the evolution of the first pandemic of the 21st century."

Click "source" to view. Read More

TWiV 356: Got viruses?

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 291: Ft. Collins abuzz with virologists

Vincent, Rich, and Kathy and their guests Clodagh and Ron recorded this episode at the 33rd annual meeting of the American Society for Virology at Colorado State University in Ft. Collins, Colorado.

Hosts: ... Read More

April 2011 Microbe feature article--Marine Microorganisms, Biogeochemical Cycles, and Global Climate Change

The April 2011 issue of Microbe is now online and includes the feature article

Marine Microorganisms, Biogeochemical Cycles, and Global Climate Change
by Jonathan P. Zehr, Julie Robidart, and Chris Scholin
Global environmental change demands a deeper understanding of how marine micro... Read More

Will the iPad Replace Your Lab Notebook?

The release of the iPad this week may bring the long-expected replacement of the paper-bound lab notebook by electronic notebooks one step closer. But are scientists, particularly PIs, comfortable with electronic lab notebooks?

The rise of the tablets
The concept of an electronic lab noteboo... Read More

Larry Brilliant Speaks About Bird Flu at Google

A candid conversation with Larry Brilliant about pandemic bird flu (H5N1), the risks we face, the uncertainties, and to talk about the accuracy and inaccuracies in the mass media. This talk was presented in May of 2006, but it's interesting to watch in light of the current media environment arou... Read More

BacterioFiles 202 - Controlling Coliform Computers

This episode: Programming bacteria to sense and keep genomic records of environmental inputs!

(15.9 MB, 17.4 minutes)

Show notes: 
Read More

TWiP 98: Resistance is not futile

The TWiP-lets reveal Balamuthia infection in the Children from Peru, and discuss resistance to pyrethroids uncovered by RNA sequencing of Anopheles mosquitoes.

Hosts:  Read More

Digitizing Biology with J. Craig Venter

A video from the DOE JGI '09 User Meeting on March 27, 2009 featuring Craig Venter's keynote talk "Reading and Writing the Genetic Code."

Read More

TWiM 57 Letters

Wink writes:

Great HAI work! I'm not through it yet. I want to question, though, whether fomites are really important in influenza transmission. I don't think so.
Wink Weinberg (ID)

[flu can transmit by fomites in guinea pigs: Read More


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Hosts: Vincent Racaniello, Alan Dove, Read More

TWiP 59 letters

Allan writes:

You have the best podcast on the web, hands down. I use your TWiP episodes in both my undergraduate and graduate classes.

I've recently seen a family in Hawaii with recurrent pathogenic Blastocystis hominis and Dientamoeba fragilis a... Read More

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