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Getting Started with MicrobeWorld

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Interview with Tom Shenk about mBio, ASM's new open access journal

Tom Shenk is not only ASM’s Publications Board Chairman and a Princeton Professor, he’s also an instigator and a mastermind (in the well-intentioned and insightful senses of the words). After all, he was one of the original forces behind starting up mBio and his ideas and work continue to drive ... Read More

Magic in Solution: An Introduction and Brief History of PCR

If you missed the opportunity to hear Carl Wittwer talk about the history of PCR and his invention of the LightCycler, the video is now available on line.

The polymerase chain reaction (PCR) has become a fundamental tool in molecular research and clinical testing. Our presenter, Carl Witter, ... Read More

TWiV 262: Wrong form, right professor

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Host: Vincent Racaniello


Guest: Read More

TWiV 375: Zika and you will find

Hosts: Vincent RacanielloAlan DoveRich Condit Read More

Prof. Racaniello's Viral Vaccines and the Principles of Immunization (Lecture)

Below is a lecture by Vincent Racaniello, Professor of Microbiology at Columbia University Medical Center and host of the popular This Week in Virology podcast, he presented on viral vaccines for the Immunology course at the Morningside Heights campus of Columbia University. Racaniello uses poli... Read More

Of Terms in Biology: Colloids

Colloid may not be a common term in biology these days, but in the early 20th century, colloids were believed to hold the key to the secrets of life. So what is a colloid? According to the Encyclopaedia Britannica it is any substance consisting of particles substantially larger than atoms or ord... Read More

Video Presentations from Princeton's 2009 Spring Biosecurity Seminar Lectures

Here's a collection of presentations from Princeton's 2009 Spring Biosecurity Seminar Lectures. Presentations include:


Feb. 20 - George Hughes Senior Advisor, Counterterrorism and Intelligence FDA Office of Criminal Investigations
Title: " Read More

TWiP 42 Letters

Jesse writes:

Dear Doctor's Racaniello and Despommier,


Huzzah! I have tracked down Dick's missing book on tropical medicine, or at least another copy of said book. While listening to TWIP #40, my ears perked up when Dick said he had lent a book to a student only to h... Read More

TWiV 364: It's not SARS 2.0

Hosts: Vincent Racaniello Read More

Viral bioinformatics: Dotplot

Dotplots are an extremely useful way of visualizing comparisons of small and large DNA sequences (as well as protein sequences), providing insight into the degree of similarity, deletions, insertions and direct and indirect repeats. In a dotplot, each nucleotide, or small window of nucleotides, ... Read More

TWiV 217: I just flu in and my arms are shot

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Hosts: Vincent Racaniello, Alan Dove, Read More

BacterioFiles Micro Edition 155 - Cells Save Superannuated Sequences

This episode: Bacteria are able to incorporate DNA from the environment into their genomes, even if it's thousands of years old!


(9.6 MB, 10.5 minutes)


Show notes: 
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Notable Bacteria



  • Bacillus anthracis causes anthrax, a deadly disease in cattle and a potential bioweapon against humans




  • .Brucella abortus causes breeding losses in livestock.




  • Cyanobacteria (formerly known as blue-green algae) live in water, where they prod... Read More

TWiM 54 Letters

Jacob writes:


Hi all,

Saw this media release from the Australian Institute of Marine Science about researchers isolating a combination of probiotic bacteria to assist in the prevention of Vibrio infections of spiny lobsters in aquaculture and thought of TW... Read More

Repair DNA

Developing tricks and tools to keep their enzymes in order is one way thermophiles survive. They also use techniques to keep their DNA from falling apart under intense heat. Like proteins, the parts of the long, spiral ladder-shaped DNA molecule start to unravel and break apart under high hea... Read More

TWiV 376: The flavi of the week is Zika

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 305: Rhymes with shinola

Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States.


Hosts:  Read More

BacterioFiles Micro Edition 57 - Rods Reduce Radioactivity

This episode: Bacteria extend little hairs that could help clean up radioactive contamination!


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Read More

TWiP 68 letters


Tim writes:


I listened to the latest TWIP this morning. Dickson mentioned the herbicide atrazine but thought it was a fungicide. It is actually a herbicide in the photosynthesis inhibitor class. Another bit of trivia about ag chemicals is that old chemicals like ... Read More

BacterioFiles Micro Edition 72 - Microbes Manipulate Mosquito Messages

This episode: Bacteria on your skin affect your attractiveness to mosquitoes!



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Read More

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