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Motility mechanism of malaria pathogens explained

How do one-celled parasites move from the salivary gland of a mosquito through a person's skin into red blood cells? What molecular mechanisms form the basis for this very important movement of the protozoa? A team of researchers headed by Dr. Friedrich Frischknecht, head of a research group at ... Read More

BacterioFiles 169 - Microbes Meddle with Mesophilic Malaria

This episode: Ambient temperature seems to affect how much insect bacteria can interfere with transmission of malaria!


(7.85 MB, 8.5 minutes)


Show notes: 
... Read More

Cell Organization and Cell Motility (Part 1) by Julie Theriot

This lecture covers the biochemical basis of actin-based motility (focusing on the pathogen Listeria as a model system for this process), the biophysical mechanism of polymerization-based force generation, and an evolutionary perspective of cell shape in prokaryotes and eukaryotes. The first par... Read More

The D225G change in 2009 H1N1 influenza virus

Last year a mutation in the HA gene of the 2009 H1N1 influenza virus was identified in isolates from patients with severe disease. At the time I concluded that the emergence of this change was not a concern. Recently the Norwegian Institute of Public Health reported that the mutation, which caus... Read More

New Coronavirus Related to Viruses From Bats

The virus that is causing alarm among global public health authorities after it killed a man in Jeddah, Saudi Arabia earlier this year and is now linked to two other cases of disease is a novel type of coronavirus most closely related to viruses found in bats, according to a genetic analysis to ... Read More

TWiV 223: EEEV and the serpent



Hosts: Vincent Racaniello, Read More

BacterioFiles Micro Edition 38 - Competitor Curbs Cavities

This episode: Bacteria may help prevent cavities!




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Myra McClure on XMRV

Myra McClure, Professor in the Division of Infection and Immunity, University College of London, U.K., has focused on retroviruses for much of her research career. I discussed the potential role of the retrovirus XMRV in prostate cancer and chronic fatigue syndrome with Dr. McClure during ICAAC ... Read More

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Outbreak of Salmonella Infection (1954)

A film commissioned by the U.S. Air Force that shows a demonstration of what happens during the course of a Salmonella outbreak. The video examines source and means of contamination, factors aiding the survival and transfer of the organism, conditions of environment and general food handling pra... Read More

Toxoplasmosis: A T.Gondii Host-pathogen interactome

This parasite interacts with many host proteins and modifies the expression of many more genes creating an interactome with almost 3000 links. In addition it exchanges substrates and metabolites with the host, modifying many biochemical parameters. T.Gondii disrupts multiple signalling network... Read More

The Ghost Map - Author Steven Johnson on the 1854 Cholera Outbreak in London

Author Steven Johnson discusses The Ghost Map, his book about a cholera outbreak in 1854 London and the impact it had on science, cities and modern society. Read More

TWiP 69 letters


Richard writes:


Hi Vincent and Dickson,


I enjoy TWIP, and often recommend it to my students. I'm a parasitologist, primarily a Leishmaniac, but I have learnt a lot from TWIP. I find it both more educational and entertaining than Car Talk.


The disc... Read More

E.O. Wilson: Help build the Encyclopedia of Life

As noted entomologist E.O. Wilson accepts his 2007 TED Prize, he makes a plea on behalf of his constituents, the insects and small creatures, to learn more about our biosphere. Wilson states that as we're still discovering tiny organisms indispensable to life we're steadily, methodically, and vi... Read More

BacterioFiles 158 - Partners Provide Protein

This episode: Different bacteria working together can thrive better than when working alone!


(9.9 MB, 10.75 minutes)


Show notes: 
News item/ Read More

TWiP 52 Letters

Jason writes:


Hi Drs. Despommier and Racaniello,


This week you wondered why the immune-activating receptor for Toxoplasma gondii, TLR11, is present in mice but not in humans. You noted that it looks like there's no selective pressure keeping it around in us an... Read More

Microbiology, Art, and Pedagogy

In this blog entry, I discuss some recent work at the intersection of art and microbiology. I go on to show how this intersection can be useful in the classroom. Read More

TWiV 252: Who read the last email?



Hosts: Vincent Racaniello, Dickson Despommier, Read More

TWiV 226: Taking the viral A train with Terry Dermody



Hosts: Vincent Racaniello, Dickson Despommier, and Read More

El podcast del Microbio Nº188 y 189. El experimento de Miller-Urey



























El podcast del Microbio Nº188 and 189 describes the famous experiment about prebiotic synthesis of organic compounds and t... Read More

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