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New Evidence for Polyomavirus BK Role in Prostate Cancer

Prostate cancer is the leading cause of cancer morbidity and the third greatest cause of cancer death among men in developed countries. A major question in cancer research has been whether virus infection plays a role in cancers of the genitourinary tract. Now a team of Swiss investigators has n... Read More

TWiV 95 Letters

Jim writes:

Some listeners might benefit from reading "The Treatment; why is it so difficult to develop drugs for cancer" in the May 17, 2010 issue of The New Yorker, a nine page article (pp 68-77).


This link goes to the digital edition ( http://archives.newyorker.co... Read More

SketchyMicro teaches Klebsiella, Serratia and Enterobacter in a really memorable way!

SketchyMicro is a unique and effective way to learn high-yield medical microbiology for the USMLE Step 1.

They take all of the microorganisms, infectious diseases, and random facts that you need to memorize for USMLE Step 1, and weave them into easy-to-remember sketches.

They narrate as th... Read More

From a food blender to real-time fluorescent imaging

Although Avery, MacLeod, and McCarty showed in 1944 that nucleic acid was both necessary and sufficient for the transfer of bacterial genetic traits, protein was still suspected to be a critical component of viral heredity. Alfred Hershey and Martha Chase showed that this hypothesis was incorrec... Read More

Development of an HIV-1 Specific Microbicide Using Caulobacter crescentus

A recent paper published in PLoS One looks at the strategy of manipulating surface proteins on the aquatic bacterium, Caulobacter crescentus, to prevent HIV infection.

Abstract:

The development of alternative strategies to prevent HIV infection is a global public health priority. Initial e... Read More

Time's Up

Merry Youle of the Small Things Considered blog has a new post up that looks at the phage-encoded holin timer and its function in a lytic infection.

"Holins are the smallest known biological timers. Timers, not clocks. Timers tick along, then go off after the specified interval. These small, ... Read More

Put Your Hands Together

Scientists estimate that people are not washing their hands often or well enough and may transmit up to 80% of all infections by their hands. From doorknobs to animals to food, harmful germs can live on almost everything. Handwashing may be your single most important act to help stop the spre... Read More

TWiV 240: Virology in Vermont

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Host: Vincent Racaniello


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El podcast del microbio Nº203: Antiguos eucariotas no marinos (earliest non-marine eukaryotes)



























El podcast del Microbio Nº203 is dedicated to Earth’s earliest non-marine eukaryotes, a discovery published in Nature journ... Read More

Herpes simplex: Host Viral interactions database

This is a database of Herpes simplex (HSV-1) host/viral interactions hosted at WikiGenes. It provides a global snapshot of what the virus does in different compartments at all stages of the viral life-cycle from entry to exit. The database is interactive, and any researcher can edit the page or ... Read More

Paleovirology—Modern Consequences of Ancient Viruses

Here's an interesting essay published in PLoS Biology by Michael Emerman and Harmit S. Malik on paleovirology, a topic recently discussed by Welkin Johnson, on the Small Things Considered blog.


<... Read More

El Podcast del microbio Nº 193 Con un poco de azúcar (A spoonful of sugar)



























El podcast del Microbio Nº193 describes the mBio 2010 paper by Huang et al. about the use of β-Glucan Particles to stimulat... Read More

TWiV 220: Flu watches the clock while T7 gets a CAT scan

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Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler<... Read More

Compiling a list of reporters who cover #microbiology stories well; suggestions wanted

I am attempting to compile a list of reporters who do a good job covering microbiology related topics. I have compiled a partial list and am soliciting additional suggestions. Read More

TWiP 53 Letters

John writes:


Dear Vincent and Dickson,


I just heard your most recent TWIP. Please keep these podcasts going! I love listening to your podcasts and hearing your enthusiasm for my favorite biological topic, parasites. Remember that for every fan... Read More

Microbial Warfare in the Underworld: Searching for New Antibiotics

This month we talked with Dr. Christine Salomon, Assistant Professor at the Center for Drug Design in the University of Minnesota. Dr. Salomon’s work intersects chemistry and microbial ecology in the hunt for interesting new natural products with far reaching potential applications. While much... Read More

A Guide to Swine Flu (SciAm)

As swine influenza reaches the U.S., a guide to what you need to know and what happens next. Plus, a look at pandemics past... Read More

BacterioFiles Micro Edition 29 - Mid-air Microbial Mix

This episode: A sample of bacteria in city air!


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BacterioFiles 166 - Metamorphosis Microbes Mapped

This episode: Discovering how butterflies' bacteria change from caterpillar to adult!


(7.5 MB, 8.1 minutes)


Show notes: 
News item/ Read More

Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade

Using genetic dissection and photothermal nanoblade delivery, a recent paper published in PNAS by Jeff F. Miller, MD., Chair, Microbiology, Immunology, & Molecular Genetics, UCLA, and others, presents data that suggest that the primary means for intercellular spread of Burkholderia pseudomallei ... Read More
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