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KEGG pathway analysis of 1443 HIV-1/host interactions

There are 1443 host viral interactions in the NCBI database. These were pumped through a KEGG pathway analsis, providing a useful insight into the multiple processes affected by HIV-1 infection. These include life cycle pathways , endocytosis and the like, but also many immune-related pathways a... Read More

Sign Up for the Scrub Club

The Scrub Club created by NSF International is designed for children who are 3 to 8 years of age. The web site is a fun, interactive and educational resource that teaches children about the microbes that make them sick and the proper way to wash their hands. The site is a hodgepodge of fun flash... Read More

BacterioFiles Micro Edition 34 - Social Slime’s Sorus Storage

3This episode: Slime molds farm their own bacterial food!




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TWiV 194: Five postdocs in North America



Hosts: Vincent Racaniello, Matthew Daugherty, Jondavid deJong, Hel... Read More

TWiV 178: T-Sharp on how tequila mosquito



Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Read More

TWiV 187 Letters

Don writes:


thank you all for sharing your knowledge in such a comprehensible manner. Thank you also for your stand against bureaucratic censorship in the H5N1 research, and your win. I have two questions. Is H5N1 a highly specific test for a human ge... Read More

TWiV 192: Viral tertulia



Hosts: Vincent Racaniello, Alan Dove, and  Read More

TWiV 181 Letters

Spencer writes:


I would like to propose the book:


Netter's Infectious Diseases, 1e as a lis... Read More

TWiV 186: From Buda to stump grinding



Hosts: Vincent Racaniello, Alan Dove, and Read More

TWiV 138: RISCy business with Raul Andino



Hosts: Vincent Racaniello and Raul Andino


Vincent meets up w... Read More

Antigen Switching in Malaria - A Classroom Activity

High school students and their teachers participate in a simple activity to demonstrate the interaction between the var antigens malaria parasites display and the patient's immune system. Read More

TWiP 38 Letters

Carlos writes:


Dear Vincent Racaniello and Dickson Despommier


I am an avid listener of TWIP since its start, have been following TWIV for at least two years and, surprise, also follow TWIM.


My field is Computer Science, but I crave for... Read More

TWiV 148: Retreating into Harvard virology



Hosts: Vincent Racaniello, Read More

Detecting viral proteins in infected cells or tissues by immunostaining

Many virological techniques are based on the specificity of the antibody-antigen reaction. Examples in our virology toolbox include western blot analysis and ELISA. While very useful, these methods cannot be used to visualize viral proteins in infected cells or tissues. To do that we must turn t... Read More

TWiV 173: Going to bat for flu research



Hosts: Vincent RacanielloAlan Dove Read More

TWiV 170: From variolous effluvia to VLPs



Hosts: Alan DoveRich Condit, and Dickson Despommier<... Read More

Virus Adaptation and Treatment - A paradigm linking herpes- virus immediate-early gene expression apoptosis and myalgic encephalomyelitis chronic fatigue syndrome

Multiple viruses have been linked to ME/CFS suggesting that multiple pathogens cause the same disease or several diseases with core signs and symptoms. Or if you are on Team XMRV /MuLV - a retrovirus could be the mastermind. No matter how you slice it in science, questions beget theories which... Read More

TWiP 16 Letters

Tom writes:


Dear Mr. Racaniello and Dick,


Thanks for TWIV and TWIP as both are great shows. Such a give and take of history, information and humor. Stumbled across TWIP several weeks ago and gave it a try. My only disappointment was there were not many podc... Read More

TWiM 31 Letters

Peter writes:

Dear TWiM Team


A fascinating article from New Scientist this week.


Standard medical teaching is that the foetus is sterile and that the microbiome only begins to develop post natal.


New research from Spain indicates that the microbiome s... Read More

TWiV 142: Viral oinkotherapy



Hosts: Vincent Racaniello, Rich Condit... Read More

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