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TWiV 125 Letters

Todd writes:


Hey Docs!


I'm a computer programmer who listens to podcasts on my long commute. The highest science education that I've had was college Chemistry. As an Electrical Engineer the science classes we took tended to not be biology oriented, so while so... Read More

Building Community through Public Toilets

The Global Water Challenge (GWC) is a coalition of leading organizations in the water and sanitation sector. In this video GWC finalist David Kuria of Ecotact Limited, a Kenyan company dedicated to bringing public toilets to an area where there were only two for 60,000 people, discusses the need... Read More

TWiP 69 letters


Richard writes:


Hi Vincent and Dickson,


I enjoy TWIP, and often recommend it to my students. I'm a parasitologist, primarily a Leishmaniac, but I have learnt a lot from TWIP. I find it both more educational and entertaining than Car Talk.


The disc... Read More

TWiV 262: Wrong form, right professor

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Host: Vincent Racaniello


Guest: Read More

From a food blender to real-time fluorescent imaging

Although Avery, MacLeod, and McCarty showed in 1944 that nucleic acid was both necessary and sufficient for the transfer of bacterial genetic traits, protein was still suspected to be a critical component of viral heredity. Alfred Hershey and Martha Chase showed that this hypothesis was incorrec... Read More

TWiV 221: Bunya there, done that

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Hosts: Vincent Racaniello, Dickson Despommier, and Read More

TWiV 77

Wladimir writes:


In regard to your question as to cases of known alteration of host behavior by virus that increases the rate of contact among hosts (Twiv 70), the most dramatic example is given by rabies. This extraordinary virus can convert a neurologically and behaviorally... Read More

Dissection of the Burkholderia intracellular life cycle using a photothermal nanoblade

Using genetic dissection and photothermal nanoblade delivery, a recent paper published in PNAS by Jeff F. Miller, MD., Chair, Microbiology, Immunology, & Molecular Genetics, UCLA, and others, presents data that suggest that the primary means for intercellular spread of Burkholderia pseudomallei ... Read More

Whooping cough predicted to double in 20 years, new vaccination strategies will be needed

A new paper in PLoS recommends two vaccination strategies to better prevent whooping cough.

"In the absence of adolescent or adult vaccination, pertussis incidence among adults is predicted to more than double in 20 years. Implementing an adult program in addition to childhood and adolescent... Read More

TWiM 54 Letters

Jacob writes:


Hi all,

Saw this media release from the Australian Institute of Marine Science about researchers isolating a combination of probiotic bacteria to assist in the prevention of Vibrio infections of spiny lobsters in aquaculture and thought of TW... Read More

BacterioFiles 173 - Illuminated Invader Inhibits Irritation

This episode: Virus helps to modify mice such that certain colors of light can cause or prevent pain!


(10 MB, 10.8 minutes)


Show notes: 
Jour... Read More

Airway Microbiota and Pathogen Abundance in Age-Stratified Cystic Fibrosis Patients

Abstract - Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other ecological niches, influenced by autogenic and allogenic factors. However, our understanding of microbial colonization in younger versus older CF airways and the association with pulmonary function ... Read More

TWiV 315: Must be something in the water

Vincent, Alan, Rich and Kathy discuss the association of a virus with sea star melting disease, and the finding of a phycodnavirus in the oropharynx of humans with altered cognitive functions.


Hosts: Vincen... Read More

Universal influenza vaccines

The need to re-formulate the influenza virus vaccine in response to viral antigenic drift and shift makes for complex logistics of vaccine production and administration. Surveillance programs must be conducted each year to identify strains that are likely to predominate and cause disease. Wouldn... Read More

BacterioFiles 174 - Synthetic Cells Sense and Send Signals

This episode: Bacteria with engineered circuits can detect and keep a record of stuff in their environment, like in the gut!


(14.6 MB, 15.9 minutes)


Show notes: 
Read More

BacterioFiles Micro Edition 144 - Copper Chelator Calms Quicksilver

This episode: Bacteria could reduce mercury's toxicity in their environment!


(6.5 MB, 7 minutes)


Methanotrophs (bacteria that use methane for their carbon and energy) secrete siderophore-like compounds that are usually used to chelate copper and make it more bioavailable, but ... Read More

BacterioFiles 162 - Desert Dwellers Densify Dunes

This episode: Spraying cyanobacteria could turn deserts into useful land!


(9.3 MB, 10.13 minutes)


Show notes: 
Ne... Read More

BacterioFiles Micro Edition 29 - Mid-air Microbial Mix

This episode: A sample of bacteria in city air!


Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Read More

Common Sense Advice for People Concerned About H1N1 (Swine Flu)

The New York Times has published a nice FAQ ,if you will, about H1N1 and what the general public should keep in mind in terms of worry, protection and symptoms. The article also talks about what public health response is feasible and should be expected. Read More

TWiM #89: Microbial handoffs

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

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