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GW Researcher Adapting Breakthrough Technologies to Combat Parasitic Worm Infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approx... Read More

Complex Life Owes Its Existence To Parasites?

Is complex life rare in the cosmos? The idea that it could be rests on the observation that the existence of life like us – with large, energy hungry, complicated cells – may be contingent on a number of very specific and unlikely factors in the history of the Earth. Added together they suggest ... Read More

Positive clinical results indicate vaccine candidate is highly efficacious against bacterial diarrhea

New results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate that a live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease. This repr... Read More

Team discovers how microbes build a powerful antibiotic

Researchers have made a breakthrough in understanding how a powerful antibiotic agent is made in nature. Their discovery solves a decades-old mystery, and opens up new avenues of research into thousands of similar molecules, many of which are likely to be medically useful.

Click "source" to r... Read More

Bacteria Allow Woodrats to Eat Poison

This article was first published in 2013 on the website for the Society of Integrative and Comparative Biology.

Many plants do not want to be eaten. They avoid this fate by producing deadly toxins and carcinogenic poisons, such as those associated with the aptly named poison ivy, poison sumac... Read More

Millions of Doses of Ebola Vaccine to Be Ready by End of 2015

The World Health Organization (WHO) announced plans on October 24 to produce millions of doses of two experimental Ebola vaccines by the end of 2015.

Hundreds of thousands of doses should be available to help affected countries before the end of June, the WHO said at the conclusion of a meeti... Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!


(10 MB, 10.8 minutes)


Show notes: 
News item/ Read More

TWiV 308: The Running Mad Professor

Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.


Host: Vincent Racaniello Read More

Mineralization of sand particles boosts microbial water filtration

Mineral coatings on sand particles actually encourage microbial activity in the rapid sand filters that are used to treat groundwater for drinking, according to a paper published ahead of print in Applied and Environmental Microbiology. These findings resoundingly refute, for the first time, the... Read More

A gut bacterium that attacks dengue and malaria pathogens and their mosquito vectors

Just like those of humans, insect guts are full of microbes, and the microbiota can influence the insect's ability to transmit diseases. A new study reports that a bacterium isolated from the gut of an Aedes mosquito can reduce infection of mosquitoes by malaria parasites and dengue virus. The b... Read More

Ebola’s evolutionary roots more ancient than previously thought, study finds

A new study is helping to rewrite Ebola’s family history.

The research shows that filoviruses — a family to which Ebola and its similarly lethal relative, Marburg, belong — are at least 16-23 million years old.

Filoviruses likely existed in the Miocene Epoch, and at that time, the evolutio... Read More

Flu viruses disguised as waste

Viruses cannot multiply without cellular machinery. Although extensive research into how pathogens invade cells has been conducted for a number of viruses, we do not fully understand how the shell of a virus is cracked open during the onset of infection thus releasing the viral genome. An ETH Zu... Read More

Without swift influx of substantial aid, Ebola epidemic in Africa poised to explode

The Ebola virus disease epidemic already devastating swaths of West Africa will likely get far worse in the coming weeks and months unless international commitments are significantly and immediately increased, new research led by Yale researchers predicts.

The findings are published in the Oc... Read More

Viral-research moratorium called too broad

Us government ban on research into enhanced pathogens also affects flu surveillance and vaccine work.

US researchers are worried that a temporary government ban on 'gain-of-function' experiments that boost the infectious properties of dangerous viruses may also cover less-extreme forms of the... Read More
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