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Getting Started with MicrobeWorld

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Study Calls into Question Current MERS Vaccine Strategy

Washington, DC - March 1, 2016 - A new study suggests that the Middle East Respiratory Syndrome coronavirus (MERS-CoV) develops mutations that make the virus less virulent during an outbreak rather than more virulent. The study, published this week in mBio, an online open-access journal of the A... Read More

Meta-analysis of urine pre-analytic practice reveals need for rigorous studies

Evidence-based medicine is the approach used by doctors to make rational clinical decisions based on rigorous, well-controlled studies. By minimizing hunches, gut feelings, and anecdotal evidence, physicians and patients can follow recommendations that are most likely to have a positive outcome.... Read More

State laws boost flu vaccination rates in health care workers

PITTSBURGH, March 2, 2016 - State laws mandating influenza immunization for people who work in health care increase their vaccination rates, according to new research led by the University of Pittsburgh School of Medicine. Read More

Trinity immunologists find new ways to beat the 'bad guys'

Vaccines are like pathogen imposters - they mimic these 'bad guys' in order to provoke a response from our immune systems, remove the invader and begin the healing process.

One of the key components in a vaccine is an adjuvant, which serves to enhance our body's immune response to vaccination... Read More

MMP #10: Examining the gut microbiota of American Indians of Cheyenne and Arapaho ancestry.

Host: Jeff Fox with special guests, Cecil M. Lewis, Jr. and Krithivasan Sankaranarayanan.


Lewis and Krithivasan Sankaranarayanan—“Krithi”-- both fro... Read More

MERS research yields surprising finding

In 2015, an unexpectedly large outbreak of Middle East Respiratory Syndrome coronavirus (MERS-CoV) in South Korea had a disastrous impact on the whole country and highlighted scientists limited knowledge of this virus. Now, new research into this outbreak has revealed some very surprising findin... Read More

Penn study reveals how fish control microbes through their gills

Oriol Sunyer, a professor at the University of Pennsylvania School of Veterinary Medicine, has described fish as "an open gut swimming." Their mucosal surfaces -- their skin, digestive tract and gills -- are in constant contact with water, including any pathogens that that water may contain. Read More

How Forest Loss Is Leading To a Rise in Human Disease

In Borneo, an island shared by Indonesia and Malaysia, some of the world’s oldest tropical forests are being cut down and replaced with oil palm plantations at a breakneck pace. Wiping forests high in biodiversity off the land for monoculture plantations causes numerous environmental problems, f... Read More

Anti-bacterial fabric holds promise for fighting superbug

Antibiotics have proven to be a valuable weapon in the fight against infectious bacteria. However, due to the excess use of antibiotics in conventional treatments, overtime antibiotics have become less effective. Read More

Electron microscopy captures snapshot of structure coronaviruses use to enter cells

High-resolution cryo-electron microscopy and supercomputing have now made it possible to analyze in detail the infection mechanisms of coronaviruses. These viruses are notorious for attacking the respiratory tract of humans and animals. Read More

BacterioFiles 241 - Colon Colonizers Control Cancer Combat

This episode: Gut microbes enhance the effectiveness of cancer therapies!


(10.7 MB, 11.7 minutes)


Show notes: 
News ... Read More

TWiV 378: Herpes plays DUBstep

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

TWiP 104: La maladie du sommeil

Michael returns to help the TWiP trio solve the case of the Delusional African Expatriate, who then discuss the association of natural and induced antibodies in mice with differential susceptibility to secondary cystic echinococcosis.


Hosts:  Read More

Zika diagnostics in a nutshell

One of the first challenges is in properly diagnosing Zika infection. Diagnosis is challenging for several reasons: first, many infected individuals don’t suffer severe symptoms. Those that do have relatively non-specific symptoms of low-grade fever, headaches, and muscle soreness that are somet... Read More

Zika virus: Approaching the unknown

Understanding the scale and range of neurological disease associated with Zika virus infection is an urgent priority, warn researchers from the University of Liverpool's Institute of Infection and Global Health. Read More

Insecticide-treated nets may still prevent malaria despite mosquito resistance

Insecticide-treated nets may still help prevent malaria despite mosquitoes developing resistance, according to a new study published in Parasites & Vectors. Read More

TWiM #122: Mayonii, microRNAs and the microbiome

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome. Read More

TWiM 122 Letters

Hunter writes:


Greetings TWiM crew!
 
I recently learned of a new game (currently getting ready for Alpha and crowd funding) where players will edit microbes at the genetic level and pit them against microbes created by other players. The game is called... Read More

Genomic sequencing reveals link between STIs and leading cause of infectious blindness

For the first time, genome sequencing has been carried out on Chlamydia trachomatis (C. trachomatis), a bacteria responsible for the disease Trachoma - the world's leading infectious cause of blindness, according to a study in Nature Communications. Read More

Zika epidemic highlights need for priority vaccine research for pregnant women

The recent outbreak of Zika virus disease and its link to fetal development highlights the need for pregnant women and those of reproductive age to be a priority group for developing and evaluating new vaccines and vaccine guidelines for Zika and other emerging infectious diseases, say the autho... Read More

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