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Human Microbiome Journal Club: The Pros of Probiotics

We’ve all heard the claims of probiotic yogurts and their benefits for human health, but aside from improving our belly dancing skills, what exactly are probiotic bacteria doing?

An elegant study from the Jeffrey Gordon lab explored the effects of consuming fermented milk products (FMPs) cont... Read More

Moffitt Cancer Center Researchers Discover How Cancer Cells “Hijack” a Mechanism to Grow

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have discovered a mechanism that explains how some cancer cells “hijack” a biological process to potentially activate cell growth and the survival of cancer gene expression.

Their study appeared in a recen... Read More

Scientists: 10,000 germ species can live in/on healthy people

They live on your skin, up your nose, in your gut - enough bacteria, fungi and other microbes that collected together could weigh, amazingly, a few pounds.

Now scientists have mapped just which critters normally live in or on us and where, calculating that healthy people can share their bodi... Read More

Computer-Designed Proteins Programmed to Disarm Variety of Flu Viruses

Computer-designed proteins are under construction to fight the flu. Researchers are demonstrating that proteins found in nature, but that do not normally bind the flu, can be engineered to act as broad-spectrum antiviral agents against a variety of flu virus strains, including H1N1 pandemic infl... Read More

Copy of the genetic makeup travels in a protein suitcase

Scientists from the Institute for Physical and Theoretical Chemistry at the University of Bonn have succeeded for the first time in the real time filming of the transport of an important information carrier in biological cells that is practically unmodified. This paper has now been published in ... Read More

Slow-Motion Microbes Still Living off Dino-era "Lunch Box"

Buried under the seafloor for 86 million years, a bacterial community lives so slowly it's still surviving on a "lunch box" from dinosaur days, a new study says. (See marine-microbe pictures.)

It's been known since the 1990s that microbes can live trapped in ocean sediments for millions of ye... Read More

New study maps hotspots of human-animal infectious diseases and emerging disease outbreaks

A new global study mapping human-animal diseases like tuberculosis (TB) and Rift Valley fever finds that an "unlucky" 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. The vast majority occur in low- and middle-income countries.

The report, wh... Read More

Study upholds immune system’s role in autism

Changes in an overactive immune system can contribute to autism-like behaviors in mice, new research shows.

Scientists at the California Institute of Technology (Caltech) pioneered the study of the link between irregularities in the immune system and neurodevelopmental disorders such as auti... Read More

Friendly Fungi: Elucidating the fungal biosynthesis of stipitatic acid

In a tale worthy of Sherlock Holmes, scientists in the School of Chemistry at the University of Bristol, UK have solved a biochemical mystery that had previously proven elusive for 70 years: How the fungus Talaromyces stipitatus produces stipitatic acid (6), which is a tropolone, one of an atypi... Read More

High School Senior Presents Poster At American Society for Microbiology 112th General Meeting (press release)

Kathleen Maguire, a Marlborough High School Senior, is presenting a poster at the American Society for Microbiology (ASM) Conference in San Francisco on June 16-19. In order to attend the conference, Maguire became a special member of the society. She is the first high school student to have a p... Read More

Jekyll and Hyde bacteria aids or kills, depending on chance

Living in the guts of worms are seemingly innocuous bacteria that contribute to their survival. With a flip of a switch, however, these same bacteria transform from harmless microbes into deadly insecticides.

In the current issue of Science, Michigan State University researchers led a study t... Read More

Tending the Body’s Microbial Garden

For a century, doctors have waged war against bacteria, using antibiotics as their weapons. But that relationship is changing as scientists become more familiar with the 100 trillion microbes that call us home — collectively known as the microbiome.

“I would like to lose the language of warfa... Read More

EP67 Protein May Prevent Flu By Boosting Immune System, Mouse Study Suggests

Scientists may have pinpointed a potential way to prevent the flu by identifying a protein that amps up the immune system, according to a new animal study.

The synthetic protein, called EP67, is able to trigger an immune response to the "threat" of the flu virus within a couple of hours in mi... Read More

Small Comfort: Nanomedicine Able to Penetrate Bodily Defenses

Researchers use stealthy nanoscale particles to infiltrate vaginal mucus and keep herpes at bay in mice.

Tears and a runny nose can be unpleasant on a windy day, but these mucosal secretions play a vital role in protecting the body from viruses and other malicious microbes. Unfortunately, muc... Read More

Titan's tides reveal hidden ocean that could host life

Alien hunters take note: a global water ocean potentially bigger than all those on Earth combined, is sloshing beneath Titan's icy crust.

Combined with the cocktail of organic chemicals already known to exist on Titan, abundant water could make the moon prime real estate for life – though mor... Read More

TWiM 34 Letters

Peter writes:

Dear TWiM Team


I see that some action is now being taken in America against the non-therapeutic use of antibiotics as livestock growth promoters:


Read More

TWiV 188: Haggis, single malt, and viruses



Hosts: Vincent Racaniello, Mass... Read More

Aaron J. Shatkin, 77

Aaron J. Shatkin was well known for his work on reoviruses beginning in the 1960s in his laboratory at the Roche Institute of Molecular Biology in Nutley, NJ and then at Rutgers University. He was among the first to appreciate that virus particles contained many different enzymes, such as RNA po... Read More

Is it Ebolavirus or Ebola virus?

When I drafted my article for TakePart (Don’t Panic – Ebola Isn’t Heading For You), I used the term ‘ebolavirus’ throughout, but the editors changed every instance to ‘Ebola virus’. Understanding which term is correct is far more complicated than you might imagine. Read More

The Extra Pounds You Can't Afford to Lose: An Interview With Microbiologist Margaret McFall-Ngai

Recent revelations about our microscopic partners and tenants are numerically startling, if not downright existential. Try these for starters: Most of the cells within your body are not human cells, and you are literally teeming with pounds of busy microbes, working to earn their keep while you ... Read More

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