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A role for siderophores in Klebsiella pneumoniae pathogenesis

Despite increasing awareness of Klebsiella pneumoniae as a public health risk, there has been relatively little understood about its mechanisms of pathogenesis.

The bacterium, estimated to be the third most common cause of hospital-acquired infections in the United States in a recent study, c... Read More

Diagnostic guidelines for bloodstream infections aim to shorten time to accurate therapy

One of the most dangerous places for an infection to occur is in the bloodstream. Septicemia, when microbes are present in the blood, not only allows bacteria access to other internal organs through the highway of our circulatory system, but also can cause a massive inflammatory response, leadin... Read More

Human handouts could be spreading disease from birds to people

Athens, Ga. - People feeding white ibises at public parks are turning the normally independent birds into beggars, and now researchers at the University of Georgia say it might also be helping spread disease. Read More

Immune response to flu vaccine linked to recipients' ethnic background

BOSTON -- How well a flu shot protects you from the virus can depend on your ethnic background and other inherited factors, report Dana-Farber Cancer Institute scientists. Read More

New hybrid drug plugs the hole in malaria drug resistance

A combination of artemisinin and another drug (artemisinin combination therapy, ACT) is currently the best malaria treatment recommended by the World Health Organization. In early 2015, artemisinin-resistant malaria was confirmed in five countries in Southeast Asia: Cambodia, Laos, Myanmar, Thai... Read More

Study sheds light on why parasite makes TB infections worse

Scientists have shown how a parasitic worm infection common in the developing world increases susceptibility to tuberculosis. The study demonstrated that treating the parasite reduces lung damage seen in mice that also are infected with tuberculosis, thereby eliminating the vulnerability to tube... Read More

MMP #14: A look at several microorganisms involved with electricity.

Host: Jeff Fox with special guests, Gemma Reguera and Geoffrey Gadd.


Gemma Reguera of Michigan State University in East Lansing and Geoffrey Gadd of the University of Dundee in Scotland talk with Jeff Fox about their efforts, to probe some of the electrical properties of materials pro... Read More

GUT BACTERIA MAY BE BEST DEFENSE AGAINST NASTY GERMS

Antibiotic-resistant bacteria are on the rise, making it more and more difficult to treat infections. But research suggests that the best defense against harmful bugs could be a healthy population of “good” gut bacteria. Read More

TWiEVO 3: Recombination is for the birds

In episode #3 of the new science show This Week in Evolution, Nels and Vincent examine another important driver of evolution: recombination. The results of two papers in which the process is studied in finches and in yeast lead to the unexpected conclusion that recombination evolves more slowly ... Read More

Bid to beat baby chest infection boosted by immune study

Babies at risk of a serious lung infection could be helped by a therapy based on the body's natural immune defences. Read More

Antiviral therapy prolongs survival in immune tolerant hepatitis B patients

April 15, 2016, Barcelona, Spain: A new study, presented today at The International Liver Congress™ 2016 in Barcelona Spain, demonstrates that the use of antiviral therapy for patients in the immune tolerant phase of Hepatitis B (HBV) prolongs overall survival and reduces the risk of the most co... Read More

Will you share? Social versus selfish mechanisms affect selective conditions

The previous post mentioned the onset of antibiotic resistance as one of the scarier, if less sensationalist, outbreaks of our time. We generally discuss antibiotic resistance in medically relevant microbes (on this blog and in the news), where resistance means the ability of disease-causing mic... Read More

Antimicrobial in Common Toothpaste Doesn't Impact Gut, Oral Microbiome

Washington, DC - May 18, 2016 - Personal hygiene products such as soaps and toothpastes that contain the antibiotic triclosan do not have a major influence on microbial communities or endocrine function, according to a small, randomized trial. The study findings were published online May 18th in... Read More

Rubella virus and birth defects

Amidst the fear surrounding Zika virus, remember that there are over 100,000 children born each year with birth defects caused by infection with rubella virus.

Rubella virus is a member of the Togaviridae family, which also includes chikungunya virus. The genome is a 9.7 kilobase, positive st... Read More

Multi-tasking Flu Vaccine Could Provide Better Protection against Outbreaks

Washington, D.C.—October 27, 2015—Australian researchers have found a way to boost the effectiveness and cross-protective capabilities of an influenza A vaccine by adding a simple component. Published this week in mBio, an online open-access journal of the American Society for Microbiology, the ... Read More

Estrogen protective against flu virus in women but not men, study suggests

Estrogen dramatically reduced the amount of flu virus that replicated in infected cells from women but not from men, a new study by researchers at the Johns Hopkins Bloomberg School of Public Health shows. Read More

Shiga toxin: no preassembly required

The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More

Gene signature could lead to a new way of diagnosing Lyme

Researchers at UC San Francisco and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene "signature" they discovered in white blood cells of patients infected with the tick-borne bacteria. Read More

Research points to development of single vaccine for Chikungunya, related viruses

What if a single vaccine could protect people from infection by many different viruses? That concept is a step closer to reality. Read More

One microbial pathogen 'disguised' as another leads to misdiagnoses

If it looks like a duck and quacks like a duck, it’s likely a duck – so goes the saying that illustrates the simplest explanation is usually the right one. But what about duck decoys used in conjunction with bird calls? Misidentification can be a deadly error – and the same goes for microbes. Mi... Read More
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