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Smut, but the Safe For Work Kind, unless you work with plants....

So I told ccondayan I would post something lewd to MicrobeWorld (who probably thought I was joking). And what could be more lewd than genuine smut? Of course, since this is MicrobeWorld, I'm posting about the group of fungal plant pathogens referred to as smut. When I worked in a plant pathol... Read More

Portraits of Microbiologists Using Luminous Bacteria as "Paint."

My wife Jennifer Quinn​ hits it out the park: a portrait of Kenneth Nealson​ and the late Woody Hastings "painted" with luminous bacteria, giving them props for the early days of quorum sensing---where the basic principles were first uncovered in bioluminescent microbes. This principle of "aut... Read More

TWiP 91 letters


Heather writes:

Dear Dr.s R, D & G,

I really hate to criticize learned professors, especially my elders. I suspect I may be being overly - sensitive or perhaps it is a cultural difference. However, the "over-talking" is decreasing the qualit... Read More

TWiM 97 Letters

Dennis writes:
hi Doc,

A paper just published in nature:


reports an effective antibiot... Read More

Latest technology could help curb repeat Ebola crisis, experts say

Recent developments in surveillance technology could enable a swifter, more effective response to potentially deadly outbreaks of disease, a study has found. Read More

TWiP 83 letters

Robin writes:

Malaria: shaking chills & fever (followed by sweats, not specifically mentioned in this case), is a characteristic of malaria that is unforgettable once one has had it (I had malaria four times).

Thick blood smears is de rigueur.
So... Read More

MdlM 111: Microbiologia en lugares exoticos con Erin Symonds

El tratamiento de aguas residuales en comunidades pequeñas y virus como indicadores de riesgo a la salud pública: estos son dos de los temas a discutirse en la entrevista de hoy con Erin Symonds, una estudiante doctoral de la Universidad de Sur de la Florida.

Read More

CRISPR/Cas9 used for rapid functional study of cancer-causing genes

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their ca... Read More

New gene a key to fighting sepsis

Scientists have identified a gene that could potentially open the door for the development of new treatments of the lethal disease sepsis. Read More

Unlikely Element Turns up in Enzyme; Commercial Renewable Fuels Might Ultimately Result

Washington, DC – August 14, 2015 - Tungsten is exceptionally rare in biological systems. Thus, it came as a huge surprise to Michael Adams, PhD., and his collaborators when they discovered it in what appeared to be a novel enzyme in the hot spring-inhabiting bacterium, Caldicellulosiruptor besci... Read More

BacterioFiles 215 - Plasmid Pirates Piezophile Particles

This episode: Deep-sea thermophile bacteriophage is pirated by another scurvy genetic element!

(10.2 MB, 11.2 minutes)

Show notes: 
J... Read More

Lingering lymphocytes lash out against Leishmania

Immune cells that hang around after parasitic skin infection help ward off secondary attack, according to a study in The Journal of Experimental Medicine. These skin squatters may prove to be the key to successful anti-parasite vaccines. Read More

TWiV 319: Breaking breakbone

The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.

Hosts: Vincent Racaniello Read More

MGH team broadens utility of more compact CRISPR-Cas9 by increasing its targeting range

A team of Massachusetts General Hospital (MGH) investigators has shown that a method they developed to improve the usefulness and precision of the most common form of the gene-editing tools CRISPR-Cas9 RNA-guided nucleases can be applied to Cas9 enzymes from other bacterial sources. In a paper r... Read More

TWiM #115: Profiling the Poglianos

Host: Vincent Racaniello

Special guests: Kit Pogliano and Joe Pogliano

Vincent visits the laboratories of Kit and J... Read More

TWiV 362: Gotta catch 'em all

Hosts: Vincent RacanielloDickson DespommierAlan Dove, Read More

Research Ushers in New Era of Boutique Chocolate

Washington, DC – November 20, 2015 - A team of Belgian researchers has shown that the yeasts used to ferment cocoa during chocolate production can modify the aroma of the resulting chocolate. “This makes it possible to create a whole range of boutique chocolates to match everyone’s favorite flav... Read More

TWiV 314: Einstein goes viral

Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells.

Host:  Read More

Microbiomes could hold keys to improving life as we know it

A consortium of 48 scientists from 50 institutions in the United States - including Pamela Silver, Ph.D., a Core Faculty member at the Wyss Institute for Biologically Inspired Engineering at Harvard University - are calling for a Unified Microbiome Initiative that would span national cross-insti... Read More

TWiP 82 letters

Allan writes:

Dear Vincent, Dickson and Daniel,

I like your idea of a TWIP coffee mug prize (or maybe a mug discount).

In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

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