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Genomic sequencing illuminates recent Shigella outbreaks in California

In a study that could have significant impact on how disease outbreaks are managed, researchers at UC Davis and the California Department of Public Health (CDPH) have sequenced and analyzed genomes from Shigella sonnei (S. sonnei) bacteria associated with major shigellosis outbreaks in Californi... Read More

Summer Travel and the Zika Virus #rio2016

Health officials have warned pregnant women to avoid travel to the more than 45 countries and territories in which the Zika virus is circulating. Infection during pregnancy can lead to birth defects in infants, particularly brain damage and abnormally small heads, called microcephaly.

But wit... Read More

Natural predatory bacteria could combat drug resistance problem

While bacteria have been evolving for 3.5 billion years, mammals have evolved with bacteria for only 2.5 million years. Thus, it's not that surprising that humans appear to be losing the war on antibiotic resistance.
The issue of multidrug-resistance and the lack of antibiotics in the developme... Read More

Zika Virus On and In the Brain - @profvrr has a new blog!

Read in near real-time a virologist's experiments on Zika Virus. Now with its fourth post the Zika Diaries aims to illuminate the public on what it takes to do research on this emerging outbreak. From the Racaniello Lab at Columbia Univ. -

"Now that my laboratory obtained a number of differe... Read More

Molecular Analysis and Expression of bap Gene in Biofilm-Forming Multi-Drug-Resistant Acinetobacter baumannii. Reports of Biochemistry & Molecular Biology 2016

Abstract

Background: Acinetobacter baumannii is commonly resistant to nearly all antibiotics due to presence of antibiotic resistance genes and biofilm formation. In this study we determined the presence of certain antibiotic-resistance genes associated with biofilm production and the influen... Read More

Reconstructing a lichen's molecular architecture

Chemist Pieter Dorrestein’s laboratory group has been developing mass spectrometry methods to look at what molecules are produced by microbes interacting in a petri dish. But recently, the group jumped out of the dish and into the dirt—to analyze a soil-dwelling lichen and discover how the molec... Read More

How our immune system targets TB

Every 18 seconds someone dies from tuberculosis - it is the world’s most deadly infectious disease.

Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), has infected more than one-third of the human population with an annual death toll of approximately 1.5 million people.

... Read More

Virus Watch: How Mosquitoes Spread Viruses

In this episode of Virus Watch, I explain how mosquitoes spread viruses. We’ll look at how a mosquito finds a host, how it finds a blood vessel, and how it delivers viruses to a new host. Don’t blame mosquitoes for viral diseases: it’s not their fault!

https://www.youtube.com/watch?v=7wsk8a3z... Read More

Zika virus placental infection differs in maternal- and fetal-derived tissues

The World Health Organization downgraded the spread of Zika virus from a Public Health Emergency of International Concern on November 22nd, but Zika virus infection remains an important emerging infection with an incompletely understood infection cycle. The better scientists understand how the v... Read More

Gonorrhea May Soon Be Resistant to all Antibiotics

The Centers for Disease Control and Prevention has reported that the wily Neisseria gonorrhoeae bacteria may be developing resistance to the only two antibiotics left that can cure the sexually transmitted disease.
The drugs, azithromycin and ceftriaxone, are used in combination to treat gonorr... Read More

Bill to provide $1.1 billion Zika funding dies in Senate vote

WASHINGTON — The Senate on Tuesday blocked a $1.1 billion bill to combat the Zika virus, giving Congress just two weeks to try to reach a new deal before lawmakers leave for a seven-week recess in the midst of mosquito season and a growing public health crisis. Read More

Why attend ABRCMS? Students discuss their experiences

Students are the focus of the Annual Biomedical Research Conference for Minority Students (ABRCMS) meeting, held most recently November 9-12, 2016, in Tampa, Florida. Undergraduate and postbaccalaureate students make up over half the roughly 4,000 program participants, and many participants belo... Read More

A minimal cell operating system

If the DNA sequence of a cell is like the operating system of a computer, then the smallest cellular OS has just been written. Called Syn3.0, it encodes everything needed to make a viable, autonomously replicating cell.

Mycoplasma is a genus of bacteria that are the smallest known free-living... Read More

BacterioFiles 287 - Producing Potent Pathogen Prophylaxes

This episode: Polymer-coated bacteria make really good vaccines!


(9.2 MB, 10 minutes)


Show notes: 


News item



Jou... Read More

Study shows how H. pylori causes white blood cells to morph

Researchers with the Iowa City VA Health Care System and University of Iowa have produced striking new evidence of neutrophil plasticity, or the ability of these white blood cells to change their properties.

The scientists exposed neutrophils—the most prevalent white blood cells—to Helicobact... Read More

Meet Luca, the Ancestor of All Living Things

A surprisingly specific genetic portrait of the ancestor of all living things has been generated by scientists who say that the likeness sheds considerable light on the mystery of how life first emerged on Earth.

This venerable ancestor was a single-cell, bacterium-like organism. But it has a... Read More

Dispatches from ASM Microbe - Friday

ASM Microbe is the new conference that merges the former General Meeting with the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) to make one microbial sciences-packed meeting with something for everyone. Why institute one new meeting instead of maintaining two separate ... Read More

TWiM 144 Letters

Kayla writes:


Hey there TWIM team


I am a Veterinary Microbiologist in Cork in Ireland!


Long time listener of all the TWIX series and I love everyone of them.


I work in a diagnostic lab in cork and the only thing that gets me through the day is ... Read More

E. coli: The ideal transport for next-gen vaccines?

BUFFALO, N.Y. - Most people recoil at the thought of ingesting E. coli. But what if the headline-grabbing bacteria could be used to fight disease? Read More

Age of the Microzoo

In 3500 BCE, Egyptian rulers built a menagerie of exotic creatures within the ancient capital of Hierakonpolis. Archaeologists have found 112 animal skeletons at this site: the first zoo on Earth. But from this earliest exhibition of the natural world through today’s most famous animal displays,... Read More
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