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$7 million grant aids efforts to eliminate neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received a $7 million grant from the Bill & Melinda Gates Foundation aimed at eliminating river blindness and elephantiasis, two neglected tropical diseases that annually sicken millions. Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

TWiM 104 Letters

Mark writes:

Hello TWiM-aggregate,

Its warm and sunny Spring weather here in California’s Bay Area. The fourth year
of Drought is upon us - please send water.

Speaking of water, below is a humorous incident that could be used to draw
attentio... Read More

TWiM 98 Letters


Patrick writes:

Hi Vincent,

I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More

My first "Mu-Tube" video promoting microbial literacy: What does "microbiology" mean to students?

For my Microbiology course at the University of Puget Sound, I decided to ask my new crop of "micronauts" what the word "microbiology" meant to them on the first day of class. Here are their answers. My wife Jennifer Quinn and I put this together using art from former students. Hopefully, thi... Read More

TWiV 326: Giving HIV a flat tyr

Hosts: Vincent RacanielloAlan Dove, and  Read More

TWiP 80 letters

Jessica writes:

Hello Dr Racaniello and Despommier,

I recently saw an article about the paper linked below on Science Daily and thought it might be worth a discussion on TWIP. It is about the possibility of bed bugs being a vector for T. cruzi. I would love to... Read More

Scientists are Working on Making Drugs More Biodegradable

BOC Sciences-Wild animals were found carrying drug resistance though they are living in areas where few human activities are existing. This finding makes scientists think about how to prevent the situation from deteriorating and protect water from being polluted furtherly. From the previous blog... Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.

Hosts: Vincent Racaniello Read More

'Ensemble' modeling could lead to better flu forecasts, study finds

By combining data from a variety of non-traditional sources, a research team led by computational epidemiologists at Boston Children's Hospital has developed predictive models of flu-like activity that provide robust real-time estimates (aka "now-casts") of flu activity and accurate forecasts of... Read More

Paper-based test can quickly diagnose Ebola in remote areas (video)

BOSTON, Aug. 18, 2015 -- When a fever strikes in a developing area, the immediate concern may be: Is it the common flu or something much worse that requires quarantine? To facilitate diagnosis in remote, low-resource settings, researchers have developed a paper-based device that changes color, d... Read More

Guinea reports Ebola-free week, but Sierra Leone has 5 cases

For the first time in more than a year, Guinea passed a week without a new lab-confirmed Ebola case, but the news out of West Africa last week was tempered by a flare-up of activity in Sierra Leone, the World Health Organization (WHO) reported today in its latest update. Read More

TWiV 324: Viruses in the miR may appear more numerous

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Studies raise questions about impact of statins on flu vaccination in seniors

A new pair of studies suggests that statins, drugs widely used to reduce cholesterol, may have a detrimental effect on the immune response to influenza vaccine and the vaccine's effectiveness at preventing serious illness in older adults. Published in The Journal of Infectious Diseases, the find... Read More

New Drug for Chemotherapy Induced Vomiting and Nausea Was Approved by FDA

BOC Sciences-Varubi also named as rolapitant, gained approval from FDA. And it’s said the drug went into its third phase clinical trial. Till now about 2800 patients have involved in the trial. Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

Portraits of Microbiologists Using Luminous Bacteria as "Paint."

My wife Jennifer Quinn​ hits it out the park: a portrait of Kenneth Nealson​ and the late Woody Hastings "painted" with luminous bacteria, giving them props for the early days of quorum sensing---where the basic principles were first uncovered in bioluminescent microbes. This principle of "aut... Read More

Breast cancer drug beats superbug

Researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have found that the breast cancer drug tamoxifen gives white blood cells a boost, better enabling them to respond to, ensnare and kill bacteria in laboratory experiment... Read More

Yet another reason to avoid methamphetamine: negative effects of meth on wound healing

Dr. Luis Martinez was on a dream vacation with his three boys. Far from their native New York home, they were traveling along the California coast with the ultimate stop at Disneyland. Unfamiliar with the roads, Martinez took a wrong turn outside of Fresno and found himself in a less pleasant pa... Read More

Vitamin C can be Helpful in Improving Blood Vessel Constriction

BOC Sciences-Latest study on vitamin C shows that it can play a positive role in improving blood vessel constriction with almost equal effect as walking. In the study, the exercise of a protein which is the main factor of blood vessel constriction was compared with the effect of vitamin C on bl... Read More
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