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Permissive vaccines and viral virulence

A permissive vaccine prevents disease in the immunized host, but does not block virus infection. Would a permissive vaccine lead to the emergence of more virulent viruses?

This hypothesis is based on the notion that viruses which kill their hosts too quickly are not efficiently transmitted, a... Read More

Toilet waste provides knowledge about diseases' global transmission routes

Current international disease surveillance systems are mainly based on reports made by doctors after treatment of infected patients. As a consequence, disease-causing microorganisms and resistance bacteria have time to spread and make large population groups sick before they are detected. Read More

A Compound from Beet Juice is Beneficial to Heart Failure Treatment

BOC Sciences-Scientists team from Washington University inspired by their previous study on beet juice that athlete drink for better muscle performance, and found nitrate existing in the juice can be helpful in the treatment of heart failure. Read More

Crime-scene compound may be newest tool in fight against malaria

The compound that detectives spray at crime scenes to find trace amounts of blood may be used one day to kill the malaria parasite. Read More

Partnership to develop production system for exciting new antibiotic

Researchers from Plymouth University are collaborating with world-leading industrial biotechnology and synthetic biology business Ingenza, to develop an efficient, scalable microbial production system for epidermicin, a new class of antibiotic being developed for use in the fight against infecti... Read More

Statistical advances help unlock mysteries of the human microbiome

Advances in the field of statistics are helping to unlock the mysteries of the human microbiome--the vast collection of microorganisms living in and on the bodies of humans, said Katherine Pollard, a statistician and biome expert, during a session today at the 2015 Joint Statistical Meetings (JS... Read More

TWiM 119 Letters

Jeanne writes:


Dear TWiM,
 
With regard to the question about culturing gut microbes from Drosophila:
 
I was lucky enough to take a sabbatical in the lab of Dr. Angela Douglas (http://angeladouglasl... Read More

Likely Drug Interactions In Placenta Could Harm Fetus

Washington, DC - October 13, 2015 - To date, studies in pregnant women examining transport of drugs across the placenta are rare and inadequate, said Tomo Nabekura, PhD. Such knowledge could be vital to preserving fetal health. In a new laboratory study, Nabekura and colleagues have illuminated ... Read More

Intestinal worms 'talk' to gut bacteria to boost immune system

EPFL researchers have discovered how intestinal worm infections cross-talk with gut bacteria to help the immune system. Read More

Prion contamination in the emergency room

Here is a follow-up to last week’s article that described a case of variant Creutzfeldt-Jacob disease in a Texas resident caused by ingestion of BSE-contaminated beef 14 years ago.

A 59 year old male patient was admitted to the trauma unit in Lancaster, PA with a self-inflicted gunshot wound ... Read More

TWiM #125: A minimal cell operating system

A deep sequencing study of commercially available probiotics, and design and synthesis of a minimal bacterial genome are the topics tackled by Vincent, Michael, and Michele on this episode of TWiM.


Hosts: Vincent Racaniello, Read More

Synthetic DNA vaccine against MERS induces immunity in animal study

PHILADELPHIA - A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. Read More

UV light robots cut c. diff transmissions by 25 percent on cancer patient floors

SAN DIEGO--Robots are capable of all sorts of tasks to help better treat cancer: They connect oncologists to patients remotely, make incisions, staple them shut, deliver "nano" therapies--and they clean rooms. New research from Penn Medicine infection control specialists found that ultraviolet (... Read More

Bacteria in ancient flea may be ancestor of the Black Death

CORVALLIS, Ore. - About 20 million years ago a single flea became entombed in amber with tiny bacteria attached to it, providing what researchers believe may be the oldest evidence on Earth of a dreaded and historic killer - an ancient strain of the bubonic plague. Read More

Zika virus has potential to spread rapidly through Americas

The Zika virus, possibly linked to serious birth defects in Brazil, has the potential to spread within the Americas, including parts of the United States, according to an international team of researchers who track the spread of infectious diseases. Read More

Liver damage in hepatitis C patients significantly underestimated, says Henry Ford study

DETROIT - The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the U.S. Centers for Disease Control and Prevention. Read More

HIV uses the immune system's own tools to suppress it

A Canadian research team at the IRCM in Montreal, led by molecular virologist Eric A. Cohen, PhD, made a significant discovery on how HIV escapes the body's antiviral responses. The team uncovered how an HIV viral protein known as Vpu tricks the immune system by using its own regulatory process ... Read More

BacterioFiles 244 - Rabbit Viruses Exploding Cancer

This episode: A conversation with Audiommunity hosts about a rabbit virus that may help treat cancer while preventing the treatment from killing the patient!


(39.2 MB, 42.9 minutes)


Show notes: 
Read More

Breastfeeding May Bring Children with More Risk for Toxic Chemicals

BOC Sciences-It has been long considered that breastfeeding would much better than formula milk in various aspects like the variety of nutrition and etc. However recent research found that breastfeeding may expose children to a series of industrial chemical substances that can pose harm to the i... Read More

TWiP 99 letters

 


Mark writes:


Temperature in Oklahoma is 12 degrees C today and rainy.


My guess is Tunga penetrans which is native to South America. The black point at center of itchy toe lesion is the flea which are legs, spiracles and egg laying aparatus. Fema... Read More

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