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Curious about the Human Microbiome?

The American Academy of Microbiology has released its newest report on the human microbiome. Based on the deliberations of some of the leading experts, the report answers common questions people have about this new field of science. While there is still much to be learned, this report presents t... Read More

HIV gets the zinc finger

Because all animal viruses initiate infection by binding to a receptor on the cell surface, this step has long been considered a prime target for antiviral therapy. Unfortunately, drugs that block virus attachment to cells have never shown much promise. Another approach, which is to ablate the r... Read More

TWiV 292: Medimmune goes viral

Vincent visits Medimmune and speaks with Wade, Matt, Nicole, and Ken about why they work in industry and their daily roles in a biotechnology company.


Hosts: Vincent Racaniello


Guests: Wa... Read More

Bacteria in space!

Where humans travel, bacteria will follow. If people are in space for any amount of time, bacteria are sure to thrive there so it’s good to know that there are already researchers looking at how the environment within spaceships affects bacterial populations. Work done on planktonic colonies of ... Read More

Breastfeeding increases prevalence of Lactobacilli and Bifidobacteria in infants

Breastfeeding until at least nine months of age increases prevalence in the gastrointestinal tract of Lactobacilli and Bifidobacteria, species which are known to contribute to development of a healthy immune system, according to a paper describing the establishment of the intestinal microbiota d... Read More

Two new weapons in the battle against bacteria

Proteases are vital proteins that serve for order within cells. They break apart other proteins, ensuring that these are properly synthesized and decomposed. Proteases are also responsible for the pathogenic effects of many kinds of bacteria. Now chemists at the Technische Universitaet Muenchen ... Read More

What’s eating you? The first food web inside humans suggests potential new treatments for infection

Imagine going to the doctor with an infection and being sent home with a course of drugs. Unknown to your doctor you actually have two infections. If you take the drugs will the other infection go away by itself? What if you take the drugs and the other infection gets worse? This quandary faces ... Read More

TWiP 65 letters

 


Perry writes:


Greetings Vincent and Dick,


Hooray for finally mentioning G. pulchrum in episode 62, my most favorite parasite and one worthy of further discussion. As a diagnostic veterinary pathologist, I encounter this spirurid in approximately... Read More

The Strange Connection Between Germs and Sherlock Holmes

Sherlock Holmes was as much a scientist as a detective. Maybe that’s because his creator, Arthur Conan Doyle, was influenced by a detective of science: Robert Koch, a German doctor who helped prove the existence of germs. In his new book, The Remedy, Thomas Goetz traces connections between the t... Read More

Poison-breathing bacteria

Buried deep in the mud along the banks of a remote salt lake near Yosemite National Park are colonies of bacteria with an unusual property: they breathe a toxic metal to survive. Researchers from the University of Georgia discovered the bacteria on a recent field expedition to Mono Lake in Calif... Read More

Lab-on-a-Chip Tracks Down 'Most Wanted' Microbe

A diagnostic tool that’s about the size of a credit card has identified a highly prized gut microbe.

The microbe contains interesting genetic sequences, but it has proven challenging to culture in the lab.

Researchers used the device, called SlipChip, to isolate microbes from a patient’s g... Read More

TWiV 296: The real Batman, Linfa Wang

Vincent visits the Australian Animal Health Laboratory in Geelong, Australia and speaks with Linfa about his work on bats and bat viruses.


Hosts: Vincent Racaniello


Guest:  Read More

1 in 25 patients gets infection in hospital

When antibiotics first started being used in the 1940's they were considered a "miracle drug". It seemed that bacterial infections would no longer be a problem for the world. However, recently, one gene is making it seem as though the end of antibiotics is at hand. This gene is New Delhi metallo... Read More

Fla. dolphins harbor potentially deadly bacteria

One in every three bottlenose dolphin tested in the Indian River Lagoon on Florida's Atlantic coast has antibodies to a bacteria that can make them more vulnerable to other deadly infections, according to a new study.

The finding comes as researchers struggle to figure out what has caused a r... Read More

TWiV 295: A nonslip grippe and Lassa's LAMP

The TWiVome discusses an miRNA based strategy to mitigate risk of gain of function studies, and identification of a second receptor required for Lassa virus entry.


Hosts: Vincent Racaniello,&n... Read More

Healthy Lung Microbes Keep Mice Breathing Easy

Like humans, mice start life with sterile lungs that soon get colonized by microbes, which appear to protect the lung tissue from an asthma-like reaction in the presence of dust mites.

Human cells are outnumbered ten-to-one by the microbes that thrive in and on us. Now a study finds that the ... Read More

TWiM #87: Avogadro, archaeal fossils, and ICAAC

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

Extensively drug-resistant tuberculosis hovers threateningly at Australia’s door

Hello dear TWIM'ers!

Firstly I would like to apologize in advance for my poor English skills since my native language is Portuguese. This past few years much has been the attention towards drug resistant bacteria. I am aware that a couple of your podcast touched this subject, but a few weeks ... Read More

Swirling and whirling: the movement of spherical bacteria

Research on bacterial movement tends to focus on the rod-shaped bacteria. With the aid of small waving flagella, each bacterial cell can push itself in the direction it wishes to go. They can also move in groups, forming large swarms that ripple and slide their way across Petri dishes. Spherical... Read More

Virus-induced fever might change bacteria from commensal to pathogen

Neisseria meningitidis may cause septicemia (bacteria in the blood) and meningitis (infection of the membrane surrounding the brain), but the bacterium colonizes the nasopharynx in 10-20% of the human population without causing disease. Although understanding how the bacterium changes from a com... Read More

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