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Long-term research: Slow science

The world's longest-running experiments remind us that science is a marathon, not a sprint. Although science is a long-term pursuit, research is often practised over short timescales: a discrete experiment or a self-contained project constrained by the length of a funding cycle. But some investi... Read More

Bacteriophages offer a way to fight resistant bacteria, but their use still awaits approval in the U.S.

An alternative treatment for antibiotic-resistant infections that are raising concern nationwide already exists. But there's a big problem. The treatment is not approved for use in the United States.

And it could be a decade or more for the treatment, long used in Russia, former Soviet nation... Read More

Some of My Best Friends Are Germs

I can tell you the exact date that I began to think of myself in the first-person plural — as a superorganism, that is, rather than a plain old individual human being. It happened on March 7. That’s when I opened my e-mail to find a huge, processor-choking file of charts and raw data from a labo... Read More

Gut bacteria may be key to weight loss

Normally we shudder when we think of bacteria, but a new study reveals that some of these microorganisms may be able to help us lose weight.

The study, published in the March 27 issue of Science Translational Medicine, showed that bacteria in the guts of mice changed after they had gastric by... Read More

TWiV 233: We're surrounded



Hosts: Vincent Racaniello, Rich Condit, Read More

Scientists Debate CDC Recommendations During Meningitis Outbreak

A pair of commentaries to appear in an upcoming issue of the journal Antimicrobial Agents and Chemotherapy highlight a debate within the public health community surrounding Centers for Disease Control and Prevention (CDC) recommendations for treatment of exposed individuals during last year’s fu... Read More

Dengue may rise in Florida if rival mosquitoes don’t mate

Florida dengue cases may rise in the near future due to female yellow fever mosquitoes becoming savvy about their false-flag suitors, leading to increased yellow fever mosquito populations.

When male Asian tiger mosquitoes successfully deceive yellow fever females, their matings are fruitles... Read More

Resistance to last-line antibiotic also makes bacteria resistant to immune attacks

Bacterial resistance to antibiotics is bad enough, but what if drug resistance also gives bacteria the ability to fend off attacks by the immune system? In a study in mBio this week scientists identify a lose-lose situation with colistin and Acinetobacter baumannii: bacteria resistant to colisti... Read More

Research Could Lead to E. coli O104 Treatments

Last year's German E. coli outbreak made headlines around the world in May and June as it sickened nearly 3,800 people and killed 50, distinguishing it as the single deadliest foodborne illness outbreak of all time. The outbreak was a dramatic entrance to the world stage for the microbe at the c... Read More

Dental Bib Clips Can Harbor Oral and Skin Bacteria Even After Disinfection

Researchers at Tufts University School of Dental Medicine and the Forsyth Institute published a study today that found that a significant proportion of dental bib clips harbored bacteria from the patient, dental clinician and the environment even after the clips had undergone standard disinfecti... Read More

Avian influenza H7N7 virus outbreak: Lessons for H7N9

An outbreak of high-pathogenicity avian influenza H7N7 virus that took place on 255 poultry farms in the Netherlands during 2003 has been used to provide clues about the current avian influenza H7N9 viruses in China. During the Dutch outbreak 453 humans showed symptoms of illness and 89 were con... Read More

Biosensor That Detects Antibiotic Resistance Brings Us One Step Closer to Fighting Superbugs

On May 8th JoVE will publish research that demonstrates how a biosensor can detect antibiotic resistance in bacteria. This new technology is a preliminary step in identifying and fighting superbugs, a major public health concern that has led to more deaths than AIDS in the United States in recen... Read More

Natural Soil Bacteria Pump New Life Into Exhausted Oil Wells

Technology that enlists natural soil bacteria as 21st century roughnecks now is commercially available and poised to recover precious oil remaining in thousands of exhausted oil wells, according to a scientist who spoke in New Orleans on April 8. His report on a process termed microbially enhanc... Read More

Nanocellulose Algae: The 'Super Material' Of The Future Will Be Cheap, Strong And Organic

Imagine a substance that was strong and light enough to armour soldiers, flexible and conductive enough to be turned into the next generation of flexible smartphone screens - and even absorbent enough to make tampons more effective.

Now imagine the process for making this wonder material was ... Read More

Researchers describe first 'functional HIV cure' in an infant

A team of researchers from UMass Medical School, the Johns Hopkins Children’s Center and the University of Mississippi Medical Center have reported the first case of a so-called “functional cure” in an HIV-infected infant. The finding, the investigators say, may help pave the way to eliminating ... Read More

Thymus Teaches Immune Cells to Ignore Vital Gut Bacteria

The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say.

When immune cells recognize essential gut bacteria as foreign, inflammatory bowel disease such as ulcerative colitis and Crohn's disease can be ... Read More

Global Viral Forecasting Founder Nathan Wolfe Interview (video)

Global Viral Forecasting Founder Nathan Wolfe explains how his team is searching for humanity's next great plague... so we can stop it before it spreads.

Read More

Oceans May Absorb More Carbon Dioxide

For a while, Adam Martiny and some of his fellow scientists had suspected something was not right in how researchers understand the oceans. The object of their suspicion was something called the Redfield ratio, a principle stating that, when nutrients are not limiting, ocean microorganisms alway... Read More

Pet rats as a source of hantavirus in England and Wales

Researchers report the detection of a strain of Seoul hantavirus (SEOV) in pet rats in England and Wales. The discovery followed an investigation of a case of haemorrhagic fever with renal syndrome in Wales. Hantavirus RNA was detected via real-time reverse transcription-polymerase chain reactio... Read More

A promising and difficult plan to end polio

THE WORLD witnessed only 223 polio cases last year, the lowest level in history and an impressive advance from the hundreds of thousands of children afflicted as recently as the 1980s. However, the eradication quest is not over, and the next steps look difficult. The Global Polio Eradication Ini... Read More

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